Detailed information    

insolico Bioinformatically predicted

Overview

Name   cinA   Type   Machinery gene
Locus tag   DQM45_RS09780 Genome accession   NZ_LS483388
Coordinates   1966135..1967394 (-) Length   419 a.a.
NCBI ID   WP_003083068.1    Uniprot ID   A0A4V0HEV5
Organism   Streptococcus porcinus strain NCTC10999     
Function   require for competence (predicted from homology)   
Unclear

Genomic Context

Location: 1961135..1972394
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DQM45_RS09750 (NCTC10999_01980) - 1961472..1963034 (-) 1563 WP_003082812.1 hypothetical protein -
  DQM45_RS09755 (NCTC10999_01981) - 1963160..1963465 (-) 306 WP_003084435.1 DUF1292 domain-containing protein -
  DQM45_RS09760 (NCTC10999_01982) ruvX 1963476..1963895 (-) 420 WP_003084867.1 Holliday junction resolvase RuvX -
  DQM45_RS09765 (NCTC10999_01983) - 1963892..1964161 (-) 270 WP_003083367.1 IreB family regulatory phosphoprotein -
  DQM45_RS09770 (NCTC10999_01984) spx 1964273..1964671 (-) 399 WP_093959030.1 transcriptional regulator Spx -
  DQM45_RS09775 (NCTC10999_01985) recA 1964903..1966045 (-) 1143 WP_003085104.1 recombinase RecA Machinery gene
  DQM45_RS09780 (NCTC10999_01986) cinA 1966135..1967394 (-) 1260 WP_003083068.1 competence/damage-inducible protein A Machinery gene
  DQM45_RS09785 (NCTC10999_01987) - 1967495..1968064 (-) 570 WP_003083576.1 DNA-3-methyladenine glycosylase I -
  DQM45_RS09790 (NCTC10999_01988) ruvA 1968068..1968661 (-) 594 WP_003084468.1 Holliday junction branch migration protein RuvA -
  DQM45_RS09795 (NCTC10999_01989) - 1968663..1969886 (-) 1224 WP_003082865.1 MFS transporter -
  DQM45_RS09800 (NCTC10999_01990) mutL 1969897..1971864 (-) 1968 WP_003083965.1 DNA mismatch repair endonuclease MutL -

Sequence

Protein


Download         Length: 419 a.a.        Molecular weight: 45221.98 Da        Isoelectric Point: 5.3336

>NTDB_id=1139822 DQM45_RS09780 WP_003083068.1 1966135..1967394(-) (cinA) [Streptococcus porcinus strain NCTC10999]
MKAEIVTVGTEILTGQILNTNAQFLSEKMAEIGVDVFYQTAVGDNKARLLEVLSLASKRSDLVILCGGLGPTDDDLTKQT
LASFLDRDLIFDEEARDKLDSFFASRPQSLRTANNEKQSQLIEGSIPIQNITGLAVGGLVESDGVSYVILPGPPSELIPM
VNQQLLSMLTVTQTKLYSRVLRFFGIGESQLVTVLAKVISEQTDPTIAPYAKVGEVTLRLSTKASGTIEADKKLDALEKV
ILATPSMEGTPLSQFFYGYGEDNSLSKEVVQLLKKKKKKLTAAESLTAGLFQATLANFAGISKFFSGGFVTYSMLEKSRM
LNIPLSDLQANGVVSHYTAQAMAEKARLLTESDIGISLTGVAGPDSLEGHPAGTVFIGISTEEKTDSIQIIIGGRSRSDI
RYIATLHAFNLVRKTLLKS

Nucleotide


Download         Length: 1260 bp        

>NTDB_id=1139822 DQM45_RS09780 WP_003083068.1 1966135..1967394(-) (cinA) [Streptococcus porcinus strain NCTC10999]
ATGAAGGCGGAGATTGTTACAGTAGGTACAGAAATCTTAACTGGTCAAATTCTCAATACCAATGCTCAGTTTTTATCAGA
AAAAATGGCAGAGATAGGAGTTGATGTTTTTTATCAAACAGCTGTTGGTGATAACAAAGCTCGATTACTAGAGGTCCTTT
CCCTTGCTAGTAAACGTAGTGATCTTGTTATTTTGTGTGGTGGACTTGGGCCAACAGATGATGATTTAACGAAGCAAACT
TTAGCAAGTTTCTTGGACCGTGATTTGATTTTTGACGAAGAAGCTAGAGATAAATTGGATAGTTTTTTTGCTTCTCGGCC
GCAAAGTTTACGAACTGCTAATAACGAGAAACAGTCACAGTTGATTGAAGGTTCAATTCCTATTCAAAATATTACGGGGC
TAGCGGTCGGAGGATTAGTAGAAAGTGACGGTGTTTCTTATGTTATCCTACCTGGACCACCTTCTGAGTTGATACCAATG
GTAAATCAACAGTTGTTATCTATGCTAACTGTGACTCAGACTAAGCTTTATTCGCGCGTATTACGTTTTTTTGGTATTGG
CGAAAGTCAATTAGTCACTGTTTTAGCTAAGGTCATCTCTGAGCAGACGGATCCAACAATTGCGCCATATGCAAAGGTAG
GTGAAGTAACTCTCCGTCTATCAACCAAGGCTTCAGGAACGATAGAGGCTGATAAAAAGCTCGATGCGCTTGAGAAAGTT
ATTTTAGCCACACCATCGATGGAAGGTACGCCTTTAAGTCAGTTTTTTTATGGCTATGGAGAAGATAATAGTTTATCAAA
GGAAGTCGTCCAGTTACTCAAGAAAAAAAAGAAAAAACTTACTGCAGCTGAGAGTTTAACAGCTGGACTTTTTCAGGCAA
CTTTGGCTAATTTTGCTGGGATATCAAAATTTTTCTCAGGTGGTTTTGTGACATACAGTATGTTAGAAAAGTCGAGGATG
TTGAATATTCCCTTATCTGACTTACAAGCTAATGGAGTGGTTAGCCACTATACAGCCCAAGCAATGGCCGAGAAAGCACG
GTTGTTAACTGAGTCGGATATAGGAATTAGTTTGACCGGTGTTGCAGGACCAGATTCCTTAGAGGGGCATCCGGCGGGGA
CTGTTTTTATTGGTATTTCGACAGAGGAGAAAACAGATTCTATCCAAATAATAATTGGTGGACGAAGTCGTTCTGATATT
CGTTATATAGCAACACTACATGCTTTTAATTTGGTCCGAAAAACTTTATTAAAAAGTTGA

Domains

Predicted by InterproScan.

Competence-damaged protein (CinA)

(263-416)

Damage-inducible protein CinA KH domain (CinA_KH)

(178-241)

Probable molybdopterin binding domain (MoCF_biosynth)

(5-165)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A4V0HEV5

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  cinA Streptococcus mutans UA159

68.345

99.523

0.68
  cinA Streptococcus mitis SK321

68.345

99.523

0.68
  cinA Streptococcus mitis NCTC 12261

67.626

99.523

0.673
  cinA Streptococcus pneumoniae TIGR4

67.626

99.523

0.673
  cinA Streptococcus pneumoniae Rx1

67.626

99.523

0.673
  cinA Streptococcus pneumoniae R6

67.626

99.523

0.673
  cinA Streptococcus pneumoniae D39

67.626

99.523

0.673
  cinA Streptococcus suis isolate S10

51.923

99.284

0.516
  cinA Bacillus subtilis subsp. subtilis str. 168

46.651

99.761

0.465

Multiple sequence alignment