Detailed information    

insolico Bioinformatically predicted

Overview

Name   comYA   Type   Machinery gene
Locus tag   DQM64_RS01105 Genome accession   NZ_LS483387
Coordinates   191654..192625 (+) Length   323 a.a.
NCBI ID   WP_001933355.1    Uniprot ID   -
Organism   Streptococcus agalactiae strain NCTC8187     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 186654..197625
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DQM64_RS01090 (NCTC8187_00217) rpoC 187352..191002 (+) 3651 WP_000228729.1 DNA-directed RNA polymerase subunit beta' -
  DQM64_RS01095 (NCTC8187_00218) - 191116..191481 (+) 366 WP_000285373.1 DUF1033 family protein -
  DQM64_RS01105 (NCTC8187_00219) comYA 191654..192625 (+) 972 WP_001933355.1 competence type IV pilus ATPase ComGA Machinery gene
  DQM64_RS01110 (NCTC8187_00220) comYB 192519..193562 (+) 1044 WP_223295889.1 competence type IV pilus assembly protein ComGB Machinery gene
  DQM64_RS01115 (NCTC8187_00221) comGF 193559..194014 (+) 456 WP_000793378.1 competence type IV pilus minor pilin ComGF -
  DQM64_RS01120 (NCTC8187_00222) comGG 193992..194363 (+) 372 WP_000601104.1 competence type IV pilus minor pilin ComGG -
  DQM64_RS01125 (NCTC8187_00223) comYH 194478..195452 (+) 975 WP_001008574.1 N-6 DNA methylase Machinery gene
  DQM64_RS01130 (NCTC8187_00224) - 195484..196677 (+) 1194 WP_000047534.1 acetate kinase -
  DQM64_RS01135 (NCTC8187_00225) - 196829..197035 (+) 207 WP_000798241.1 helix-turn-helix transcriptional regulator -
  DQM64_RS01140 - 197094..197231 (+) 138 WP_001865900.1 hypothetical protein -

Sequence

Protein


Download         Length: 323 a.a.        Molecular weight: 36849.37 Da        Isoelectric Point: 6.8469

>NTDB_id=1139731 DQM64_RS01105 WP_001933355.1 191654..192625(+) (comYA) [Streptococcus agalactiae strain NCTC8187]
MVQSLAKQVIHQAVEVNAQDIYIIPKGDCYELYMRIDDERRFIDVFEFNRMASLISHFKFVAGMNVGEKRRSQLGSCDYE
LSEGRLVSLRLSSVGDYRGQESLVIRILYSGHQDLKYWFDNIKQMKEVLGIRGLYLFSGPVGSGKTTLMYQLASEVFKNK
QIITIEDPVEIKNDKMLQLQLNEDIGMTYDALIKLSLRHRPDILIIGEIRDQATARAVIRASLTGVMFFSTIHAKSIPGV
YDRLIELGVNYQELENSLKLIAYQRLIGGGSLIDFETGNFKKHSSDKWNRQVDILAEEGHISKKQAQVEKIIPQETTESS
PTF

Nucleotide


Download         Length: 972 bp        

>NTDB_id=1139731 DQM64_RS01105 WP_001933355.1 191654..192625(+) (comYA) [Streptococcus agalactiae strain NCTC8187]
ATGGTTCAATCATTAGCAAAGCAAGTCATTCATCAGGCAGTAGAAGTAAATGCTCAAGATATTTATATCATTCCCAAAGG
TGATTGTTATGAACTCTATATGCGTATTGATGATGAAAGGCGGTTTATTGATGTTTTTGAGTTTAATAGGATGGCTAGTC
TTATTAGTCACTTTAAATTTGTGGCAGGCATGAACGTTGGAGAAAAAAGACGAAGTCAATTAGGTTCTTGTGACTATGAA
CTGTCAGAGGGAAGACTGGTTTCATTACGACTATCGAGTGTGGGAGATTATCGTGGTCAAGAATCTTTAGTTATTCGTAT
TTTGTATTCAGGTCATCAGGACTTAAAATATTGGTTTGATAATATAAAGCAAATGAAGGAAGTACTGGGTATAAGAGGGC
TATATCTTTTTTCCGGCCCTGTGGGGAGTGGTAAAACAACTCTCATGTATCAATTAGCTTCAGAAGTATTTAAAAATAAG
CAAATTATCACGATTGAAGATCCGGTAGAAATCAAGAATGACAAGATGTTACAACTCCAATTGAATGAGGATATTGGAAT
GACTTATGATGCTTTAATCAAACTGTCTTTACGGCATCGTCCAGATATTTTAATTATCGGAGAGATTAGAGATCAAGCGA
CGGCCCGTGCTGTTATTCGTGCAAGTTTAACGGGAGTGATGTTTTTTTCTACTATTCATGCTAAAAGTATTCCCGGAGTC
TATGATAGGCTTATAGAATTAGGGGTTAACTATCAAGAGTTAGAAAATAGTCTAAAATTAATAGCATATCAACGTTTAAT
TGGAGGAGGAAGCCTAATTGACTTTGAGACAGGTAATTTTAAAAAACACTCATCAGACAAGTGGAATAGACAAGTGGATA
TCTTGGCTGAAGAAGGACATATCAGTAAGAAACAGGCACAAGTCGAAAAAATTATCCCTCAAGAAACAACGGAAAGTAGT
CCAACTTTTTAA

Domains

Predicted by InterproScan.

Type II/IV secretion system protein (T2SSE)

(8-267)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comYA Streptococcus mutans UA159

68.489

96.285

0.659
  comYA Streptococcus mutans UA140

68.489

96.285

0.659
  comYA Streptococcus gordonii str. Challis substr. CH1

63.323

98.762

0.625
  comGA/cglA/cilD Streptococcus mitis NCTC 12261

62.379

96.285

0.601
  comGA/cglA/cilD Streptococcus pneumoniae Rx1

61.415

96.285

0.591
  comGA/cglA/cilD Streptococcus pneumoniae D39

61.415

96.285

0.591
  comGA/cglA/cilD Streptococcus pneumoniae R6

61.415

96.285

0.591
  comGA/cglA/cilD Streptococcus pneumoniae TIGR4

61.415

96.285

0.591
  comGA/cglA Streptococcus sobrinus strain NIDR 6715-7

61.613

95.975

0.591
  comGA Lactococcus lactis subsp. cremoris KW2

50.311

99.69

0.502

Multiple sequence alignment