Detailed information    

insolico Bioinformatically predicted

Overview

Name   cinA   Type   Machinery gene
Locus tag   DQM63_RS00645 Genome accession   NZ_LS483385
Coordinates   114166..115422 (+) Length   418 a.a.
NCBI ID   WP_032910581.1    Uniprot ID   -
Organism   Streptococcus sanguinis strain NCTC7863     
Function   facilitate localization of RecA (predicted from homology)   
Homologous recombination

Genomic Context

Location: 109166..120422
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DQM63_RS00605 (NCTC7863_00117) - 109683..110192 (-) 510 WP_002902024.1 RDD family protein -
  DQM63_RS00610 (NCTC7863_00118) - 110176..110679 (-) 504 WP_002902025.1 helix-turn-helix domain-containing protein -
  DQM63_RS00615 (NCTC7863_00119) ruvA 110849..111439 (+) 591 WP_032909470.1 Holliday junction branch migration protein RuvA -
  DQM63_RS00620 (NCTC7863_00120) - 111449..112021 (+) 573 WP_002914194.1 DNA-3-methyladenine glycosylase I -
  DQM63_RS00625 (NCTC7863_00121) - 112031..112879 (-) 849 WP_002902030.1 helix-turn-helix domain-containing protein -
  DQM63_RS00635 (NCTC7863_00123) - 113478..113756 (+) 279 WP_223310420.1 bacteriocin immunity protein -
  DQM63_RS00645 (NCTC7863_00124) cinA 114166..115422 (+) 1257 WP_032910581.1 competence/damage-inducible protein A Machinery gene
  DQM63_RS00650 (NCTC7863_00125) recA 115481..116629 (+) 1149 WP_002914192.1 recombinase RecA Machinery gene
  DQM63_RS00655 (NCTC7863_00126) spx 116715..117113 (+) 399 WP_002894078.1 transcriptional regulator Spx -
  DQM63_RS00660 (NCTC7863_00127) - 117249..117821 (+) 573 WP_002894077.1 SP0191 family lipoprotein -
  DQM63_RS00665 (NCTC7863_00128) - 117927..118469 (+) 543 WP_002914190.1 hypothetical protein -
  DQM63_RS00670 (NCTC7863_00129) - 118647..118913 (+) 267 WP_002894075.1 IreB family regulatory phosphoprotein -
  DQM63_RS00675 (NCTC7863_00130) ruvX 118913..119332 (+) 420 WP_002902035.1 Holliday junction resolvase RuvX -
  DQM63_RS00680 (NCTC7863_00131) - 119357..119668 (+) 312 WP_002894073.1 DUF1292 domain-containing protein -

Sequence

Protein


Download         Length: 418 a.a.        Molecular weight: 44680.90 Da        Isoelectric Point: 4.8801

>NTDB_id=1139603 DQM63_RS00645 WP_032910581.1 114166..115422(+) (cinA) [Streptococcus sanguinis strain NCTC7863]
MKAEIIAVGTEILTGQIVNTNAQFLSEKLASLGIDVYFQTAVGDNENRLLSVLEIAQGRSNLIILTGGLGPTEDDLTKQT
LAKFLGRELIFDPQAVEKLDRFFASRPDYARTPNNERQAQLVEGSTPLSNATGLAVGGLLEADGVTYVVLPGPPSELKPM
VNNELVPLLSTGQKLYSRVLRFFGIGESQLVTILAEMIEQQNDPTIAPYAKTGEVTLRLSTKALSQAEADTKFEAVEKLI
LAHKTFEGHSLSEIFYGYGDDNSLAQAAFDLLKSQGKTISAAESLTAGLFQATLADFAGASSIFSGGFVTYSMEEKSRML
DIPLGDLEKHGVVSAFTAGKMAEQARKLTESDLAVSLTGVAGPDSLEGHPAGTVFIGLASASGTEIIKVNIAGRSRRDVR
KIAVLHAFNLVRKTLLNS

Nucleotide


Download         Length: 1257 bp        

>NTDB_id=1139603 DQM63_RS00645 WP_032910581.1 114166..115422(+) (cinA) [Streptococcus sanguinis strain NCTC7863]
ATGAAAGCAGAAATTATTGCTGTGGGCACTGAGATTCTGACCGGTCAGATTGTCAATACCAATGCCCAATTTTTATCTGA
AAAACTGGCGAGTCTGGGGATTGATGTCTATTTTCAGACAGCAGTAGGGGACAATGAAAATCGTCTCCTCTCTGTTTTGG
AAATTGCTCAAGGACGCAGTAATCTAATTATCCTGACAGGAGGCTTGGGCCCAACAGAGGATGATTTGACCAAGCAAACC
TTGGCTAAGTTCTTAGGGCGCGAGCTCATTTTTGATCCTCAGGCTGTGGAAAAGCTGGATCGCTTTTTTGCTAGCCGGCC
GGATTATGCTCGAACGCCCAATAATGAGCGTCAGGCCCAGCTGGTCGAAGGCTCAACTCCGTTGTCAAATGCGACCGGCT
TAGCTGTCGGAGGATTGTTAGAAGCAGACGGAGTGACCTATGTAGTCCTGCCTGGCCCGCCTAGTGAGCTCAAGCCCATG
GTCAATAACGAGCTGGTTCCCCTCTTATCCACAGGTCAGAAATTGTATTCACGGGTGCTGCGCTTCTTTGGTATCGGCGA
GAGTCAGCTAGTGACTATTTTGGCAGAAATGATTGAACAGCAGAACGACCCCACCATTGCTCCTTATGCAAAGACAGGGG
AAGTTACCCTGCGACTGTCCACCAAGGCTCTGAGTCAGGCAGAAGCTGACACCAAGTTTGAGGCTGTGGAAAAGTTAATT
TTGGCACACAAGACTTTTGAGGGACATTCACTGTCAGAGATTTTCTATGGTTATGGGGATGACAATTCCTTGGCACAGGC
GGCTTTTGACTTGCTGAAGAGTCAAGGAAAGACGATTTCGGCGGCGGAGAGTCTGACAGCAGGGCTCTTTCAGGCGACCT
TGGCTGATTTTGCTGGAGCCTCTTCCATTTTTTCAGGTGGCTTTGTCACCTACAGCATGGAGGAAAAGAGCCGGATGCTG
GATATTCCGTTGGGAGACCTGGAGAAGCACGGTGTCGTTTCCGCTTTTACGGCTGGGAAAATGGCAGAGCAGGCTAGAAA
GCTGACCGAAAGTGACCTAGCTGTCAGTCTGACAGGTGTGGCTGGTCCAGATTCACTGGAAGGCCATCCAGCAGGGACCG
TTTTTATCGGCTTAGCAAGTGCTTCAGGAACAGAAATTATTAAGGTCAATATTGCTGGACGCAGTCGGCGTGATGTGCGG
AAAATTGCTGTTCTGCACGCCTTCAACCTAGTACGAAAAACTTTATTAAATAGCTGA

Domains

Predicted by InterproScan.

Damage-inducible protein CinA KH domain (CinA_KH)

(177-240)

Competence-damaged protein (CinA)

(262-415)

Probable molybdopterin binding domain (MoCF_biosynth)

(5-169)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  cinA Streptococcus mitis SK321

78.177

99.761

0.78
  cinA Streptococcus mitis NCTC 12261

77.698

99.761

0.775
  cinA Streptococcus pneumoniae TIGR4

77.458

99.761

0.773
  cinA Streptococcus pneumoniae Rx1

77.458

99.761

0.773
  cinA Streptococcus pneumoniae R6

77.458

99.761

0.773
  cinA Streptococcus pneumoniae D39

77.218

99.761

0.77
  cinA Streptococcus mutans UA159

75.359

100

0.754
  cinA Streptococcus suis isolate S10

55.288

99.522

0.55
  cinA Bacillus subtilis subsp. subtilis str. 168

46.89

100

0.469

Multiple sequence alignment