Detailed information    

insolico Bioinformatically predicted

Overview

Name   comB   Type   Regulator
Locus tag   DQM67_RS01785 Genome accession   NZ_LS483383
Coordinates   326404..327759 (+) Length   451 a.a.
NCBI ID   WP_005591090.1    Uniprot ID   A0AAV3EDX1
Organism   Streptococcus cristatus ATCC 51100 strain NCTC 12479     
Function   transport of ComC (predicted from homology)   
Competence regulation

Genomic Context

Location: 321404..332759
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DQM67_RS01755 (NCTC12479_00333) lepB 321658..322290 (-) 633 WP_005591096.1 signal peptidase I -
  DQM67_RS01760 (NCTC12479_00334) rnhC 322294..323178 (-) 885 WP_005591095.1 ribonuclease HIII -
  DQM67_RS01770 (NCTC12479_00335) - 323405..323578 (+) 174 WP_005592399.1 Blp family class II bacteriocin -
  DQM67_RS01775 (NCTC12479_00336) - 323611..323871 (+) 261 WP_005591092.1 hypothetical protein -
  DQM67_RS01780 (NCTC12479_00337) comA 324236..326389 (+) 2154 WP_005591091.1 peptide cleavage/export ABC transporter ComA Regulator
  DQM67_RS01785 (NCTC12479_00338) comB 326404..327759 (+) 1356 WP_005591090.1 bacteriocin secretion accessory protein Regulator
  DQM67_RS01790 (NCTC12479_00339) - 327860..328135 (-) 276 WP_005591088.1 hypothetical protein -
  DQM67_RS01795 (NCTC12479_00340) - 328145..328555 (-) 411 WP_005591086.1 HIT family protein -
  DQM67_RS01800 (NCTC12479_00341) pptA 328623..329354 (+) 732 WP_005591084.1 ABC transporter ATP-binding protein Regulator
  DQM67_RS01805 (NCTC12479_00342) - 329351..330397 (+) 1047 WP_005591082.1 ABC transporter permease -
  DQM67_RS01810 (NCTC12479_00343) ccrZ 330448..331242 (+) 795 WP_005591081.1 cell cycle regulator CcrZ -
  DQM67_RS01815 (NCTC12479_00344) trmB 331239..331877 (+) 639 WP_005591080.1 tRNA (guanosine(46)-N7)-methyltransferase TrmB -

Sequence

Protein


Download         Length: 451 a.a.        Molecular weight: 49784.77 Da        Isoelectric Point: 7.2002

>NTDB_id=1139488 DQM67_RS01785 WP_005591090.1 326404..327759(+) (comB) [Streptococcus cristatus ATCC 51100 strain NCTC 12479]
MEEHYLESAEFYNRRYSSFSVRVILPTFFLLIFVVLFSLFAKKEITITSGASIEPSKILANIQSTSNNAIVTNNLKENKV
VKKGDLLVQYKSDSENTQKETFSSQVESLKEQKRQLELLQESLKTGTSQFSGEDRFGYEQAFNDYKNQAASIRSNTEQQN
STIASQNSAASNSQAELGNLINETNAKLADYQTLRNAIQNGTSVPSTNAGYSIYQAYETQAAADSQGQLKSQVLSQIDSQ
ISQFESALAGYRVQYAGSGAQQAYSGSLDSQLESLKAQQLTKVGQELTALNQKILEVENNLKVQGGITQKGMITATEDGI
LHLNPETAGANLVPEGKLLAQLYPVLTKEKKVVITTYVTSKDVASLKKGETLRFTAMDGNNKEFVLKSKISNIDSNATKT
EKGNFFKVEAEITLTGAQAKKVRYGIEGRAVVITGSKTYFDYYLDQFLRKD

Nucleotide


Download         Length: 1356 bp        

>NTDB_id=1139488 DQM67_RS01785 WP_005591090.1 326404..327759(+) (comB) [Streptococcus cristatus ATCC 51100 strain NCTC 12479]
ATGGAAGAACATTACTTAGAGAGTGCCGAATTTTATAACCGTAGATATTCTAGCTTTTCTGTGCGCGTGATTTTACCGAC
TTTCTTCTTGTTGATTTTTGTGGTCTTATTCTCTCTCTTTGCTAAAAAAGAAATCACTATTACTTCAGGTGCTTCTATTG
AACCTAGCAAGATTCTAGCCAACATCCAATCAACCAGTAACAATGCCATTGTCACTAATAATTTGAAGGAAAATAAGGTT
GTAAAAAAAGGGGATCTTTTAGTTCAGTATAAGTCTGATAGTGAAAATACTCAAAAAGAAACTTTCTCCTCTCAAGTAGA
AAGCTTGAAGGAGCAAAAACGTCAGTTGGAGCTGCTGCAAGAAAGTCTGAAGACGGGGACTAGCCAGTTTTCAGGAGAGG
ATCGCTTCGGCTATGAGCAAGCATTTAATGATTATAAGAACCAAGCTGCGAGTATCCGTAGTAATACCGAACAGCAAAAT
TCGACCATTGCTTCTCAAAATTCAGCAGCTAGTAATTCACAGGCCGAGCTGGGGAATTTGATCAATGAAACAAATGCCAA
ATTAGCAGATTATCAGACCCTTAGAAATGCTATCCAAAATGGGACAAGTGTCCCTTCGACTAATGCTGGCTATAGCATCT
ATCAGGCTTATGAGACACAAGCCGCTGCAGATAGTCAAGGTCAGCTAAAGAGTCAGGTTCTTTCGCAAATTGATAGTCAG
ATTTCTCAGTTTGAATCAGCTCTTGCAGGTTATCGGGTGCAGTATGCGGGCTCTGGTGCTCAGCAGGCTTATTCTGGGAG
CTTGGATAGTCAGCTTGAGTCTTTGAAAGCTCAGCAGTTGACTAAAGTTGGTCAAGAATTGACGGCCTTGAATCAAAAGA
TTTTAGAAGTTGAAAACAATCTCAAGGTGCAAGGTGGTATCACTCAAAAGGGCATGATCACAGCAACTGAAGATGGTATT
CTCCACCTAAATCCTGAAACAGCAGGAGCGAATCTAGTTCCCGAAGGGAAGTTACTCGCTCAGTTGTATCCTGTTTTGAC
CAAGGAAAAAAAGGTCGTTATCACAACCTATGTGACCTCAAAAGATGTTGCTAGTCTGAAAAAAGGTGAGACTTTGCGTT
TCACTGCAATGGATGGAAATAATAAAGAATTTGTTCTCAAATCTAAAATTTCAAACATTGACAGCAATGCAACGAAAACG
GAAAAAGGAAACTTCTTTAAGGTGGAAGCTGAAATAACCTTAACGGGTGCTCAAGCCAAGAAGGTGCGTTATGGTATTGA
AGGTCGTGCAGTAGTCATCACAGGAAGCAAAACTTACTTTGACTATTACTTGGATCAATTCTTGAGAAAGGACTAA

Domains

Predicted by InterproScan.

HlyD family secretion protein (HlyD_3)

(313-425)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comB Streptococcus pneumoniae R6

57.206

100

0.572
  comB Streptococcus pneumoniae Rx1

57.206

100

0.572
  comB Streptococcus pneumoniae D39

57.206

100

0.572
  comB Streptococcus mitis SK321

57.206

100

0.572
  comB Streptococcus mitis NCTC 12261

57.206

100

0.572
  comB Streptococcus pneumoniae TIGR4

56.763

100

0.568
  comB Streptococcus gordonii str. Challis substr. CH1

54.343

99.557

0.541

Multiple sequence alignment