Detailed information NTG1139487

Bioinformatically predicted

Overview

• Name: comA
• Type: Regulator
• Locus tag: DQM67_RS01780
• Genome accession: NZ_LS483383
• Coordinates: 324236..326389 (+)
• Length: 717 a.a.
• NCBI ID: WP_005591091.1
• Uniprot ID: A0AAV3ED27
• Organism: Streptococcus cristatus ATCC 51100 strain NCTC 12479
• Function: processing and transport of ComC (predicted from homology) Competence regulation

Genomic Context

Location: 319236..331389

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DQM67_RS01755 (NCTC12479_00333)	lepB	321658..322290 (-)	633	WP_005591096.1	signal peptidase I	-
DQM67_RS01760 (NCTC12479_00334)	rnhC	322294..323178 (-)	885	WP_005591095.1	ribonuclease HIII	-
DQM67_RS01770 (NCTC12479_00335)	-	323405..323578 (+)	174	WP_005592399.1	Blp family class II bacteriocin	-
DQM67_RS01775 (NCTC12479_00336)	-	323611..323871 (+)	261	WP_005591092.1	hypothetical protein	-
DQM67_RS01780 (NCTC12479_00337)	comA	324236..326389 (+)	2154	WP_005591091.1	peptide cleavage/export ABC transporter ComA	Regulator
DQM67_RS01785 (NCTC12479_00338)	comB	326404..327759 (+)	1356	WP_005591090.1	bacteriocin secretion accessory protein	Regulator
DQM67_RS01790 (NCTC12479_00339)	-	327860..328135 (-)	276	WP_005591088.1	hypothetical protein	-
DQM67_RS01795 (NCTC12479_00340)	-	328145..328555 (-)	411	WP_005591086.1	HIT family protein	-
DQM67_RS01800 (NCTC12479_00341)	pptA	328623..329354 (+)	732	WP_005591084.1	ABC transporter ATP-binding protein	Regulator
DQM67_RS01805 (NCTC12479_00342)	-	329351..330397 (+)	1047	WP_005591082.1	ABC transporter permease	-
DQM67_RS01810 (NCTC12479_00343)	ccrZ	330448..331242 (+)	795	WP_005591081.1	cell cycle regulator CcrZ	-

Sequence

Protein

• Length: 717 a.a.
• Molecular weight: 81157.58 Da
• Isoelectric Point: 8.0275

>NTDB_id=1139487 DQM67_RS01780 WP_005591091.1 324236..326389(+) (comA) [Streptococcus cristatus ATCC 51100 strain NCTC 12479]
MRFTKRHYRAQVDARDCGVAALAMIYGYYGSYYSLASLREMAKTTLRGTTAFGLVKVSEELGFETRAFKADMSLFDMKGI
VYPFIAHVIKDKKLLHYYVVTGHDKHSVYIADPDPAVKMTKLSKEQFAQEWTGVSIFIAPAPEYRPHKEKKNGLWSFVPI
LMKQKGLIANIVIATMLVTIINIVGSYYMQGIIDTYVPNQMRNTLGIISLGLIVVYILQQVLTYAQSYLLLILGQRLSID
VILSYIKHVFHLPMSFFATRRTGEIVSRFNDANSIIDALASTILSIFLDVSIVVVMAIVLFSQNFYLFFISLLSLPIYIV
VIFAFMKPFEKMNRDTMESNAILSSSIIEDINGIETIKSLTSEDFRYQKIDREFVDYLKKSFAYSRMENIQIGLKKTAQL
LLNVAILWMGALLVMDNKMTLGQLITYNTLLVYFTNPLENIINLQTKLQTAQVANNRLNEVYLVDSEFMDKKAIRDLSMT
KGDIELRNVSYKYGYGRNVLSDINLTIERGSKVAFVGISGSGKTTLAKMIVNFYDPNEGEILVNNINLNQIDKHVLRRHI
NYLPQQPYVFNGTILENVLLGAKPGTTQKEIIRALEIAEIREDIERMPLNYQTELTSDGSGISGGQRQRLALARALLTDA
PVLILDEATSNLDILTEKKIIDNLLELDKTIIFIAHRLTIAERSEKVVVLDKGEIVEQGTHEELVAQDGFYAHLVNS

Nucleotide

• Length: 2154 bp

>NTDB_id=1139487 DQM67_RS01780 WP_005591091.1 324236..326389(+) (comA) [Streptococcus cristatus ATCC 51100 strain NCTC 12479]
ATGAGATTTACAAAGCGTCATTATAGAGCTCAAGTTGACGCGAGAGATTGTGGTGTAGCAGCGCTGGCCATGATTTATGG
TTATTATGGTTCCTATTATTCTTTGGCCAGTTTGCGTGAAATGGCCAAAACGACCTTGAGGGGAACAACTGCTTTTGGGC
TAGTGAAGGTTTCGGAAGAGTTAGGTTTTGAAACACGAGCCTTTAAAGCGGATATGTCTTTATTTGACATGAAGGGCATC
GTTTATCCTTTTATCGCCCATGTTATCAAAGACAAGAAATTGCTTCACTATTATGTTGTGACTGGGCACGATAAACATTC
GGTTTATATTGCGGATCCAGATCCGGCTGTAAAAATGACCAAGCTTTCTAAGGAACAGTTTGCGCAAGAGTGGACAGGTG
TCTCTATTTTCATCGCCCCAGCGCCAGAATATAGACCACACAAGGAAAAGAAAAACGGTCTCTGGTCTTTTGTTCCGATT
TTAATGAAACAAAAGGGACTGATTGCCAATATCGTTATTGCAACGATGCTGGTGACGATTATCAATATCGTGGGCTCTTA
CTACATGCAGGGGATTATTGATACTTACGTACCGAATCAGATGAGGAATACCTTAGGAATTATTTCTCTCGGTCTAATAG
TCGTCTACATTTTGCAACAGGTCCTGACTTATGCTCAGAGCTATCTGCTCCTCATATTGGGCCAACGCCTTTCGATTGAT
GTGATTTTGTCCTATATTAAGCATGTCTTTCATCTACCCATGTCTTTTTTTGCGACGAGAAGGACAGGGGAAATCGTATC
GCGCTTCAACGATGCCAATAGTATCATTGATGCCTTAGCTAGTACTATTCTGTCCATCTTTTTGGATGTGTCTATCGTTG
TCGTCATGGCAATTGTTTTGTTCTCACAAAACTTCTATTTGTTCTTTATCAGTTTGCTTTCGCTGCCTATCTATATCGTC
GTGATTTTCGCTTTCATGAAGCCATTTGAAAAAATGAATCGCGACACGATGGAATCCAATGCCATTCTGTCTTCTTCTAT
TATCGAAGATATCAATGGTATTGAGACGATCAAATCCTTGACAAGTGAAGATTTCCGCTATCAAAAGATTGATAGAGAAT
TTGTTGACTATCTGAAGAAATCATTTGCCTATAGTCGGATGGAAAATATCCAAATCGGCTTGAAGAAGACGGCTCAGCTC
TTGCTGAATGTTGCAATCCTTTGGATGGGAGCCCTTTTGGTAATGGACAATAAAATGACCTTGGGGCAGTTGATTACTTA
TAATACTTTGCTGGTTTATTTCACAAATCCGCTGGAAAATATTATCAATTTACAGACCAAGCTTCAGACTGCCCAAGTTG
CCAATAATCGCTTGAACGAGGTTTATCTGGTTGACTCTGAATTTATGGATAAAAAAGCGATCCGTGATTTGAGCATGACC
AAGGGCGACATTGAGTTGCGAAATGTCAGCTACAAGTATGGCTATGGACGAAATGTTCTGTCGGATATTAATTTGACCAT
TGAAAGAGGCAGCAAGGTGGCATTTGTGGGAATTTCTGGTTCTGGAAAGACGACTCTTGCCAAGATGATCGTGAACTTTT
ACGATCCAAACGAGGGAGAAATTCTGGTTAATAATATCAACCTCAATCAGATTGACAAGCATGTCTTGCGCCGTCATATC
AATTACTTGCCGCAACAGCCTTATGTCTTTAATGGTACCATTTTGGAGAATGTTCTCCTAGGTGCAAAACCCGGAACGAC
TCAGAAAGAAATCATTCGAGCGCTGGAAATTGCGGAAATTCGTGAAGATATTGAACGGATGCCTTTGAATTACCAAACAG
AATTGACATCGGATGGTTCAGGAATTTCAGGTGGTCAGCGTCAGCGCTTGGCCTTGGCTCGGGCTCTTTTGACCGATGCT
CCTGTTTTGATCCTTGATGAGGCGACCAGCAATCTGGATATCTTGACAGAGAAAAAGATCATTGACAACCTTTTGGAGTT
GGACAAGACCATCATTTTCATTGCCCATCGATTGACCATTGCGGAGCGATCTGAAAAAGTGGTTGTTCTGGACAAGGGTG
AAATCGTGGAGCAAGGGACGCATGAAGAGTTGGTTGCTCAGGATGGTTTCTATGCTCATCTGGTGAATAGTTAG

Domains

Predicted by InterproScan.

• Peptidase C39 family (Peptidase_C39) (7-142)

• ABC transporter (ABC_tran) (500-650)

• ABC transporter transmembrane region (ABC_membrane) (170-438)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comA	Streptococcus mitis NCTC 12261	79.637	100	0.796
comA	Streptococcus pneumoniae Rx1	79.358	100	0.794
comA	Streptococcus pneumoniae D39	79.358	100	0.794
comA	Streptococcus pneumoniae R6	79.358	100	0.794
comA	Streptococcus mitis SK321	79.219	100	0.792
comA	Streptococcus pneumoniae TIGR4	79.079	100	0.791
comA	Streptococcus gordonii str. Challis substr. CH1	76.29	100	0.763
comA/nlmT	Streptococcus mutans UA159	63.877	100	0.639