Detailed information    

insolico Bioinformatically predicted

Overview

Name   comX/sigX/comX2/sigX2   Type   Regulator
Locus tag   DQM89_RS08150 Genome accession   NZ_LS483382
Coordinates   1566851..1567402 (-) Length   183 a.a.
NCBI ID   WP_111721343.1    Uniprot ID   -
Organism   Streptococcus pyogenes strain NCTC13738     
Function   activate transcription of late competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1561851..1572402
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DQM89_RS08125 (NCTC13738_01618) - 1563219..1564064 (+) 846 WP_002982833.1 mechanosensitive ion channel family protein -
  DQM89_RS08130 (NCTC13738_01619) - 1564129..1564689 (-) 561 WP_002995157.1 TIGR01440 family protein -
  DQM89_RS08135 (NCTC13738_01620) - 1564703..1565173 (-) 471 WP_023610570.1 ECF transporter S component -
  DQM89_RS08140 (NCTC13738_01621) - 1565163..1565927 (-) 765 WP_002988136.1 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase -
  DQM89_RS08145 (NCTC13738_01622) truA 1565917..1566666 (-) 750 WP_002988132.1 tRNA pseudouridine(38-40) synthase TruA -
  DQM89_RS08150 (NCTC13738_01623) comX/sigX/comX2/sigX2 1566851..1567402 (-) 552 WP_111721343.1 sigma-70 family RNA polymerase sigma factor Regulator

Sequence

Protein


Download         Length: 183 a.a.        Molecular weight: 22181.00 Da        Isoelectric Point: 10.1136

>NTDB_id=1139470 DQM89_RS08150 WP_111721343.1 1566851..1567402(-) (comX/sigX/comX2/sigX2) [Streptococcus pyogenes strain NCTC13738]
MSCCFFVVLFILGIVKKKRRLKMSIGTRAAFEKVKPIILKLKRHYYIQLWDRDDWLQEGHIILLQLLERYPELIEEEERL
YRYFKTKFSSYLKDLLRRQESQKRQFHKLAYEEIGEVAHAIPSRGLWLDDYVAYQEVIASLENQLNSQERMQFQALIKGE
RFKGRRALLRKISPYFKEFAQQL

Nucleotide


Download         Length: 552 bp        

>NTDB_id=1139470 DQM89_RS08150 WP_111721343.1 1566851..1567402(-) (comX/sigX/comX2/sigX2) [Streptococcus pyogenes strain NCTC13738]
GTGTCCTGTTGCTTTTTTGTGGTTCTCTTTATACTAGGGATAGTTAAAAAGAAAAGGAGACTCAAAATGTCGATAGGGAC
AAGAGCAGCGTTTGAAAAAGTTAAGCCCATTATTTTGAAATTAAAGCGACACTATTATATTCAATTGTGGGATAGAGATG
ACTGGTTACAAGAAGGACATATTATCTTATTACAGTTACTAGAAAGGTACCCAGAGTTAATTGAGGAAGAAGAGCGTTTA
TATCGCTATTTTAAAACAAAATTTTCATCTTATTTGAAAGATTTATTACGCCGTCAAGAAAGTCAAAAGCGTCAGTTCCA
TAAGTTAGCATATGAAGAGATAGGGGAGGTTGCACATGCCATTCCATCGAGAGGGTTATGGCTAGACGACTATGTGGCTT
ATCAAGAGGTAATAGCTAGCTTAGAGAACCAATTAAATTCGCAAGAGCGTATGCAGTTTCAAGCACTTATCAAGGGCGAA
CGTTTCAAGGGAAGACGTGCTCTACTTAGGAAGATCAGTCCCTATTTTAAGGAATTTGCACAGCAGTTGTAA

Domains


No domain identified.



Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comX/sigX/comX2/sigX2 Streptococcus pyogenes JRS4

98.907

100

0.989
  comX/sigX/comX1/sigX1 Streptococcus pyogenes JRS4

98.907

100

0.989
  comX/sigX/comX1/sigX1 Streptococcus pyogenes MGAS8232

98.361

100

0.984
  comX/sigX/comX1/sigX1 Streptococcus pyogenes MGAS315

98.361

100

0.984
  comX/sigX/comX2/sigX2 Streptococcus pyogenes MGAS315

98.361

100

0.984
  comX/sigX/comX2/sigX2 Streptococcus pyogenes MGAS8232

98.361

100

0.984
  comX/sigX Streptococcus infantarius subsp. infantarius ATCC BAA-102

48.667

81.967

0.399
  comX Streptococcus sobrinus strain NIDR 6715-7

45.455

84.153

0.383
  comX/sigX Streptococcus mutans UA159

44.444

83.607

0.372

Multiple sequence alignment