Detailed information    

insolico Bioinformatically predicted

Overview

Name   comR/comR2   Type   Regulator
Locus tag   DQM69_RS00275 Genome accession   NZ_LS483381
Coordinates   42291..43193 (+) Length   300 a.a.
NCBI ID   WP_109982339.1    Uniprot ID   -
Organism   Streptococcus sobrinus strain NCTC10921     
Function   require for natural transformation (predicted from homology)   
Unclear

Genomic Context

Location: 37291..48193
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DQM69_RS00260 (NCTC10921_00053) - 38491..38649 (+) 159 WP_019768924.1 bacteriocin -
  DQM69_RS00265 (NCTC10921_00054) comR/comR1 38816..39721 (+) 906 WP_109982338.1 helix-turn-helix domain-containing protein Regulator
  DQM69_RS00270 (NCTC10921_00055) comA 39981..42098 (+) 2118 WP_019772678.1 peptide cleavage/export ABC transporter Regulator
  DQM69_RS00275 (NCTC10921_00056) comR/comR2 42291..43193 (+) 903 WP_109982339.1 helix-turn-helix domain-containing protein Regulator
  DQM69_RS00280 (NCTC10921_00057) - 43323..44195 (-) 873 WP_109982340.1 helix-turn-helix domain-containing protein -
  DQM69_RS00285 (NCTC10921_00058) - 44514..45272 (+) 759 WP_019768919.1 ABC transporter ATP-binding protein -
  DQM69_RS00290 (NCTC10921_00059) - 45275..47584 (+) 2310 WP_109982341.1 ABC transporter permease -

Sequence

Protein


Download         Length: 300 a.a.        Molecular weight: 35453.99 Da        Isoelectric Point: 5.3662

>NTDB_id=1139371 DQM69_RS00275 WP_109982339.1 42291..43193(+) (comR/comR2) [Streptococcus sobrinus strain NCTC10921]
MTMKEVLGQRIKEERESKQISQKLLCGNGAALTVRQLQRIEHGQSLPTLEKLEFIARRLDLKTSDLLESVDVQLPEDYWA
MKARIVKFPTYGEKERIQRKLDLINEVLVKYFDRLPEDELLFLDLSENILDRIHDKRIPNIEEIYDDAFEQVLKKKTFTF
NDYLYLSYFLQKCRNEASYDRKIFKQIEQKLLQQELSSDEFYNIEFLAAVMDAAAVYAFHDDYKDIMPLLKKIHWIIEQA
QLHTYKAGVLELEAKYYVKIAKDKDRAKKLYQQALKLGEILEDPAIIADIKMEMKNDGIE

Nucleotide


Download         Length: 903 bp        

>NTDB_id=1139371 DQM69_RS00275 WP_109982339.1 42291..43193(+) (comR/comR2) [Streptococcus sobrinus strain NCTC10921]
ATGACGATGAAAGAAGTTCTAGGGCAGCGGATTAAGGAAGAAAGAGAAAGCAAGCAGATCTCACAGAAGCTCCTATGCGG
GAATGGGGCAGCTCTGACTGTCCGCCAACTGCAAAGGATTGAGCATGGCCAGTCCCTGCCGACGCTGGAGAAACTGGAGT
TTATCGCCCGGCGCTTGGATTTAAAAACGTCAGACCTTCTGGAGAGTGTTGATGTCCAATTGCCAGAGGATTATTGGGCT
ATGAAGGCTCGAATCGTTAAGTTCCCCACCTATGGGGAGAAAGAGCGGATTCAACGTAAGCTGGACCTGATTAACGAGGT
TTTGGTCAAGTACTTTGATCGTCTGCCTGAGGATGAGTTGCTCTTTTTGGACCTGTCAGAAAATATCTTGGATAGGATCC
ACGATAAACGTATCCCCAATATTGAGGAAATCTATGATGATGCTTTCGAGCAGGTGCTCAAGAAGAAAACCTTTACTTTT
AATGACTACCTTTATTTGAGTTATTTTTTACAAAAGTGTCGCAATGAAGCTAGTTATGATCGAAAGATCTTCAAACAGAT
TGAGCAAAAATTACTCCAACAAGAACTGAGTTCAGACGAGTTTTATAATATTGAATTTTTGGCAGCAGTTATGGACGCGG
CTGCTGTCTATGCTTTTCATGATGATTATAAGGATATCATGCCATTGTTGAAGAAAATACATTGGATTATTGAGCAAGCC
CAACTCCACACCTATAAGGCAGGGGTTCTAGAATTAGAAGCTAAATACTATGTTAAAATCGCTAAGGATAAGGATAGGGC
CAAGAAACTTTATCAACAAGCTCTAAAGTTAGGGGAAATCTTGGAGGATCCTGCTATTATTGCAGATATTAAGATGGAAA
TGAAAAACGATGGGATTGAGTAA

Domains

Predicted by InterproScan.

Helix-turn-helix (HTH_3)

(11-65)

ComR tetratricopeptide (ComR_TPR)

(75-294)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comR/comR2 Streptococcus sobrinus strain NIDR 6715-7

100

100

1
  comR/comR1 Streptococcus sobrinus strain NIDR 6715-7

71.333

100

0.713
  comR Streptococcus salivarius strain HSISS4

42.475

99.667

0.423
  comR Streptococcus thermophilus LMD-9

42.14

99.667

0.42
  comR Streptococcus thermophilus LMG 18311

42.14

99.667

0.42
  comR Streptococcus salivarius SK126

42.14

99.667

0.42

Multiple sequence alignment