Detailed information    

insolico Bioinformatically predicted

Overview

Name   comA   Type   Regulator
Locus tag   DQM69_RS00270 Genome accession   NZ_LS483381
Coordinates   39981..42098 (+) Length   705 a.a.
NCBI ID   WP_019772678.1    Uniprot ID   -
Organism   Streptococcus sobrinus strain NCTC10921     
Function   processing and transport of ComC (predicted from homology)   
Competence regulation

Genomic Context

Location: 34981..47098
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DQM69_RS00245 (NCTC10921_00050) - 35414..36133 (+) 720 WP_109833385.1 hypothetical protein -
  DQM69_RS10720 (NCTC10921_00051) - 36375..36503 (+) 129 WP_019768926.1 hypothetical protein -
  DQM69_RS00250 - 36634..36864 (+) 231 WP_002959611.1 hypothetical protein -
  DQM69_RS00255 (NCTC10921_00052) - 37128..38465 (+) 1338 WP_019768925.1 hypothetical protein -
  DQM69_RS00260 (NCTC10921_00053) - 38491..38649 (+) 159 WP_019768924.1 bacteriocin -
  DQM69_RS00265 (NCTC10921_00054) comR/comR1 38816..39721 (+) 906 WP_109982338.1 helix-turn-helix domain-containing protein Regulator
  DQM69_RS00270 (NCTC10921_00055) comA 39981..42098 (+) 2118 WP_019772678.1 peptide cleavage/export ABC transporter Regulator
  DQM69_RS00275 (NCTC10921_00056) comR/comR2 42291..43193 (+) 903 WP_109982339.1 helix-turn-helix domain-containing protein Regulator
  DQM69_RS00280 (NCTC10921_00057) - 43323..44195 (-) 873 WP_109982340.1 helix-turn-helix domain-containing protein -
  DQM69_RS00285 (NCTC10921_00058) - 44514..45272 (+) 759 WP_019768919.1 ABC transporter ATP-binding protein -

Sequence

Protein


Download         Length: 705 a.a.        Molecular weight: 78992.61 Da        Isoelectric Point: 8.9748

>NTDB_id=1139370 DQM69_RS00270 WP_019772678.1 39981..42098(+) (comA) [Streptococcus sobrinus strain NCTC10921]
MKKYTYIAQVDERDCGVAALAMVLKHYGSTYSLAYLRELAQTSREGTSALGLIRAAQGLGLKTKAIRAQLDLFDDEHLTY
PFIVHVVKDESLQHYYTVFGQDGDKIIIGDPDPGKKVVKLPRSQFEKEWTGVALFFEPSETYTVHKEKLKGLWSFVPILL
KKKTLIAVIVAMSFMVTVINIVGSYYLQGMLDSLIPRAMYSFLTIVSLGLCLAYLAQQVFQFFQTYLLSRLSNYLAAQVI
LPYIKHVLSLPMSFFTSRRTGEITSRFGDASTIIDALASTILSLFLDLTIVITLAVTLFVQSTQLFSLTLLVVPLYALVI
LSFLKFFDHQNYQVMEANSKVNTAIIDDLRGIETLKSLRVEKRRYSSIEGKFSDYLTKSLKRSQWEAIQTSLKTIVQLVF
NVLILWYGANLVMRGQLSIGQLITYNMLLTYFTTPLTNIINLQGKLQQARVANNRLQEVYVVDKEEEAKNDVKDFTSLQL
SGVGHRFSYQQETLKDIDLSIERGDKIALMGKSGSGKTTLAKILAGYYTVNQGKTLIDERSVGYPELRSLVTYVPQQSYV
FTGTILENLLLGVSGDVDEKRLIEVCTTAEILEDIQAMPLGFQSQVSEDGGLSGGQKQRLAIARALLSDQPILVFDEATS
GLDGDTEEKVIKNLNSIDRTMIFVAHRGSISNYANRIVKIEAGKKISDQPNQKLRWSRLGLGHVV

Nucleotide


Download         Length: 2118 bp        

>NTDB_id=1139370 DQM69_RS00270 WP_019772678.1 39981..42098(+) (comA) [Streptococcus sobrinus strain NCTC10921]
TTGAAAAAGTATACCTATATTGCCCAGGTAGATGAGCGCGATTGTGGGGTGGCGGCCTTGGCCATGGTCCTTAAGCATTA
TGGATCGACCTATAGTTTGGCCTACCTTAGGGAACTGGCTCAGACCTCTCGGGAAGGAACCTCTGCCTTGGGCTTGATAA
GGGCGGCCCAAGGTTTAGGACTTAAAACCAAGGCTATCCGAGCGCAGTTAGATCTTTTTGATGATGAGCATTTGACCTAT
CCCTTTATCGTTCATGTTGTTAAGGATGAGAGTCTGCAACACTACTACACGGTCTTTGGGCAAGATGGAGATAAGATTAT
TATCGGCGATCCTGATCCTGGGAAGAAGGTTGTTAAGTTGCCACGTTCGCAATTTGAAAAAGAATGGACAGGTGTTGCTC
TTTTCTTTGAACCGAGCGAGACTTATACAGTTCACAAGGAGAAGCTTAAGGGGCTCTGGTCTTTTGTACCAATCTTACTG
AAAAAGAAGACCTTGATTGCCGTTATTGTTGCCATGAGTTTTATGGTGACCGTAATTAATATCGTTGGGTCATACTATTT
GCAAGGGATGTTGGATAGCTTGATTCCAAGAGCCATGTACTCATTTTTGACGATTGTCTCCTTAGGGCTCTGTCTTGCTT
ATCTGGCTCAACAGGTCTTCCAATTTTTCCAGACCTACTTGCTCTCTCGTCTCAGCAATTATCTAGCTGCACAGGTCATC
CTTCCTTATATTAAGCATGTCCTGTCTCTGCCGATGAGCTTCTTTACCTCTCGGCGGACTGGTGAGATTACTTCACGTTT
TGGCGATGCTAGCACAATTATTGATGCCTTAGCTTCAACGATTTTGTCACTCTTCTTGGATTTGACGATTGTTATTACCT
TGGCTGTGACCCTCTTTGTACAAAGTACACAGCTCTTTAGTTTGACCTTACTGGTGGTTCCTCTCTATGCCTTGGTGATT
CTATCCTTCCTCAAATTTTTTGATCATCAGAACTATCAGGTAATGGAAGCTAATAGTAAGGTTAACACCGCTATCATTGA
TGATTTGCGGGGGATTGAAACGCTTAAATCCCTACGAGTTGAAAAGCGGCGTTACTCTTCAATTGAAGGTAAGTTCTCAG
ATTATTTGACTAAGTCTCTGAAGCGGAGTCAGTGGGAGGCTATTCAAACGAGCTTGAAGACGATTGTCCAGCTTGTCTTT
AATGTCTTGATTCTTTGGTATGGGGCTAATTTGGTGATGCGTGGTCAACTCTCAATAGGGCAGTTGATTACCTATAACAT
GCTGCTGACCTATTTTACAACCCCCCTGACCAATATTATTAATTTGCAAGGAAAACTCCAACAAGCGCGTGTTGCTAACA
ACCGCCTCCAAGAAGTATATGTGGTTGATAAAGAAGAAGAGGCTAAAAATGATGTGAAAGACTTTACCAGCCTTCAGCTA
TCGGGTGTGGGCCATCGCTTTAGCTACCAACAAGAAACCTTAAAGGATATTGACTTATCAATTGAGCGCGGTGATAAGAT
TGCCCTGATGGGTAAGAGTGGTTCTGGTAAGACAACTTTGGCTAAGATTTTAGCGGGTTACTATACTGTAAACCAAGGTA
AAACTCTGATTGATGAGCGGTCTGTTGGTTATCCTGAATTGAGGAGTTTGGTTACCTATGTTCCCCAACAATCCTATGTG
TTCACAGGAACCATTTTGGAAAACCTCCTGCTTGGAGTGTCCGGTGATGTTGATGAGAAACGTTTGATAGAAGTTTGTAC
TACAGCTGAAATTTTAGAAGATATTCAAGCTATGCCGCTAGGCTTTCAATCTCAAGTTTCCGAAGATGGTGGCCTGTCGG
GTGGGCAAAAGCAACGGTTAGCCATTGCTCGGGCTCTGCTTTCAGACCAGCCAATTTTAGTCTTTGACGAAGCCACAAGT
GGACTTGATGGTGATACGGAAGAAAAAGTTATTAAAAATCTCAATAGTATCGATCGGACCATGATTTTTGTTGCCCACCG
AGGTAGCATCTCAAATTATGCTAACCGAATTGTTAAGATTGAGGCTGGTAAAAAAATTAGCGATCAACCCAACCAAAAAC
TCAGGTGGTCACGTTTAGGTTTAGGCCATGTTGTTTAA

Domains

Predicted by InterproScan.

Peptidase C39 family (Peptidase_C39)

(3-140)

ABC transporter transmembrane region (ABC_membrane)

(168-436)

ABC transporter (ABC_tran)

(494-640)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comA Streptococcus gordonii str. Challis substr. CH1

50.423

100

0.508
  comA Streptococcus pneumoniae D39

51.143

99.291

0.508
  comA Streptococcus pneumoniae R6

51.143

99.291

0.508
  comA Streptococcus pneumoniae Rx1

51.143

99.291

0.508
  comA Streptococcus mitis SK321

51.143

99.291

0.508
  comA Streptococcus pneumoniae TIGR4

51

99.291

0.506
  comA Streptococcus mitis NCTC 12261

51.153

98.44

0.504
  comA/nlmT Streptococcus mutans UA159

49.215

99.433

0.489

Multiple sequence alignment