Detailed information NTG1139369

Bioinformatically predicted

Overview

• Name: comR/comR1
• Type: Regulator
• Locus tag: DQM69_RS00265
• Genome accession: NZ_LS483381
• Coordinates: 38816..39721 (+)
• Length: 301 a.a.
• NCBI ID: WP_109982338.1
• Uniprot ID: -
• Organism: Streptococcus sobrinus strain NCTC10921
• Function: repress natural transformation (predicted from homology) Competence regulation

Genomic Context

Location: 33816..44721

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DQM69_RS00235 (NCTC10921_00046)	-	33851..33985 (+)	135	WP_255264604.1	ComC/BlpC family leader-containing pheromone/bacteriocin	-
DQM69_RS10715 (NCTC10921_00047)	-	34015..34143 (+)	129	WP_019768929.1	hypothetical protein	-
DQM69_RS10425 (NCTC10921_00048)	-	34198..34341 (+)	144	WP_019785178.1	hypothetical protein	-
DQM69_RS00240 (NCTC10921_00049)	-	34603..35424 (+)	822	WP_019770819.1	ABC transporter ATP-binding protein	-
DQM69_RS00245 (NCTC10921_00050)	-	35414..36133 (+)	720	WP_109833385.1	hypothetical protein	-
DQM69_RS10720 (NCTC10921_00051)	-	36375..36503 (+)	129	WP_019768926.1	hypothetical protein	-
DQM69_RS00250	-	36634..36864 (+)	231	WP_002959611.1	hypothetical protein	-
DQM69_RS00255 (NCTC10921_00052)	-	37128..38465 (+)	1338	WP_019768925.1	hypothetical protein	-
DQM69_RS00260 (NCTC10921_00053)	-	38491..38649 (+)	159	WP_019768924.1	bacteriocin	-
DQM69_RS00265 (NCTC10921_00054)	comR/comR1	38816..39721 (+)	906	WP_109982338.1	helix-turn-helix domain-containing protein	Regulator
DQM69_RS00270 (NCTC10921_00055)	comA	39981..42098 (+)	2118	WP_019772678.1	peptide cleavage/export ABC transporter	Regulator
DQM69_RS00275 (NCTC10921_00056)	comR/comR2	42291..43193 (+)	903	WP_109982339.1	helix-turn-helix domain-containing protein	Regulator
DQM69_RS00280 (NCTC10921_00057)	-	43323..44195 (-)	873	WP_109982340.1	helix-turn-helix domain-containing protein	-

Sequence

Protein

• Length: 301 a.a.
• Molecular weight: 35541.62 Da
• Isoelectric Point: 4.4380

>NTDB_id=1139369 DQM69_RS00265 WP_109982338.1 38816..39721(+) (comR/comR1) [Streptococcus sobrinus strain NCTC10921]
MTIKADLGRRIKAERNRKKISQSSFCGDEEKLTIRQLQRIEHGQSLPTLEKLEFIADRLDIKMSDLLEGRNIQLPDDYWE
MKARIVKFPTYGDEERIQQKQNLIDEIYDKYFDSLPEDELLFLDLSENILGGIHDKNIPDIEEIYDDAFDQVLKKERFDF
NDYLYLGYFLQQCRKDSDYDYKTFKKIEQKLLKQELLADDLYNIELLVTVMDAATVYAFHDDYGNIMPLLEKLNRIIDKA
QLPTYKVGLLELEAKYYIKVVEDKEKAKELYQRALMLGDILDDPTIIADVKMEMKNDGIDE

Nucleotide

• Length: 906 bp

>NTDB_id=1139369 DQM69_RS00265 WP_109982338.1 38816..39721(+) (comR/comR1) [Streptococcus sobrinus strain NCTC10921]
ATGACAATAAAAGCAGATTTGGGACGACGGATTAAGGCCGAAAGAAACCGGAAAAAAATATCGCAGAGTTCATTTTGCGG
GGACGAAGAAAAGTTAACGATTCGTCAGTTGCAGCGGATTGAGCATGGCCAATCCCTACCAACTCTAGAAAAGTTGGAAT
TTATCGCTGATCGTTTGGACATTAAAATGTCTGACCTTCTGGAAGGTAGGAATATCCAATTACCGGATGACTATTGGGAA
ATGAAAGCACGGATTGTTAAATTTCCTACCTATGGAGATGAGGAAAGAATCCAGCAAAAACAGAATCTCATTGATGAAAT
TTATGATAAATACTTTGACAGTCTACCTGAGGATGAACTGCTCTTTTTGGACCTTTCAGAAAATATTCTAGGGGGTATTC
ATGACAAGAATATTCCTGATATTGAAGAAATTTATGATGATGCCTTCGATCAGGTTCTTAAAAAGGAGAGGTTTGATTTT
AACGATTACCTTTATTTGGGCTATTTTTTGCAACAGTGTCGCAAGGATTCCGATTATGATTATAAGACTTTTAAAAAAAT
TGAGCAGAAATTACTAAAGCAGGAGCTATTGGCAGATGATCTCTATAATATTGAACTTTTAGTGACAGTAATGGATGCTG
CTACTGTCTATGCTTTTCATGATGATTATGGAAATATCATGCCCTTGTTAGAAAAACTGAATCGTATTATTGATAAAGCT
CAACTCCCCACCTACAAGGTAGGACTTTTAGAACTTGAGGCCAAGTACTATATTAAGGTTGTTGAAGATAAAGAAAAAGC
CAAAGAACTTTACCAGCGCGCTCTGATGCTGGGAGATATTCTAGATGATCCCACCATTATTGCTGATGTTAAGATGGAAA
TGAAAAATGATGGGATAGATGAATAA

Domains

Predicted by InterproScan.

• ComR tetratricopeptide (ComR_TPR) (75-294)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comR/comR1	Streptococcus sobrinus strain NIDR 6715-7	100	100	1
comR/comR2	Streptococcus sobrinus strain NIDR 6715-7	71.333	99.668	0.711
comR	Streptococcus thermophilus LMG 18311	42.14	99.336	0.419
comR	Streptococcus salivarius strain HSISS4	42.14	99.336	0.419
comR	Streptococcus thermophilus LMD-9	41.472	99.336	0.412
comR	Streptococcus salivarius SK126	41.137	99.336	0.409