Detailed information NTG1139166

Bioinformatically predicted

Overview

• Name: htrA
• Type: Regulator
• Locus tag: DQM54_RS10795
• Genome accession: NZ_LS483375
• Coordinates: 2152571..2153764 (+)
• Length: 397 a.a.
• NCBI ID: WP_111724268.1
• Uniprot ID: -
• Organism: Streptococcus gordonii strain NCTC3165
• Function: repress competence development (predicted from homology) Competence regulation

Genomic Context

Location: 2147571..2158764

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DQM54_RS10755 (NCTC3165_02141)	ychF	2147873..2148988 (-)	1116	WP_008808030.1	redox-regulated ATPase YchF	-
DQM54_RS10770 (NCTC3165_02144)	comE/comE2	2149310..2150077 (-)	768	WP_008808031.1	competence system response regulator transcription factor ComE	Regulator
DQM54_RS10775 (NCTC3165_02145)	comD/comD1	2150074..2151432 (-)	1359	WP_111724324.1	competence system sensor histidine kinase ComD	Regulator
DQM54_RS10780 (NCTC3165_02146)	comC/comC1	2151448..2151612 (-)	165	WP_080998577.1	bacteriocin	Regulator
DQM54_RS10790 (NCTC3165_02148)	rlmH	2151898..2152377 (-)	480	WP_008808034.1	23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH	-
DQM54_RS10795 (NCTC3165_02149)	htrA	2152571..2153764 (+)	1194	WP_111724268.1	S1C family serine protease	Regulator
DQM54_RS10800 (NCTC3165_02150)	spo0J	2153830..2154594 (+)	765	WP_111724269.1	ParB/RepB/Spo0J family partition protein	Regulator

Sequence

Protein

• Length: 397 a.a.
• Molecular weight: 42156.84 Da
• Isoelectric Point: 5.2632

>NTDB_id=1139166 DQM54_RS10795 WP_111724268.1 2152571..2153764(+) (htrA) [Streptococcus gordonii strain NCTC3165]
MKNSSNFFKKTLQVFIVLFVGFIGGVAGTWGLSYFSTPHSATNNNQKTATTITTSYKNSNSTTKAVDKVKDAVVSVITYS
ESSSDAIFDNNNSGNENDQVASEGSGVIYRKDKDYAYLVTNTHVINGAKKVDIRLADGNKVPGEIVGTDTYSDISVVRIP
ADKVKNVAEFGDSSKLTVGETAIAIGSPLGSDYANTVTQGIVSSLSRNVSSRSEDGQTIATQAIQTDAAINPGNSGGPLV
NIQGQVIGITSSKIANTNNGSTSVEGMGFAIPSNDVVSIIEQLEKNGKVIRPALGIQMVNLSSLSSSSSDRLKLPDNIKN
GVVVRSTQTGMPADGKLEKYDVITKIDDTEISSASDIQSALYKHSINEEIKVTYYRDGKEQTTTIKLTKSTDDLSSE

Nucleotide

• Length: 1194 bp

>NTDB_id=1139166 DQM54_RS10795 WP_111724268.1 2152571..2153764(+) (htrA) [Streptococcus gordonii strain NCTC3165]
ATGAAAAATTCTTCAAATTTCTTCAAAAAAACATTGCAAGTTTTCATTGTCTTGTTTGTTGGTTTTATAGGTGGTGTTGC
TGGAACATGGGGACTTTCTTATTTTTCAACACCTCACTCAGCCACAAATAATAATCAGAAAACAGCTACTACAATAACAA
CATCCTATAAAAATAGTAATTCTACAACAAAGGCTGTTGATAAAGTTAAAGACGCAGTTGTCTCTGTCATTACATATTCT
GAATCTAGTTCAGATGCTATTTTTGACAACAATAATTCAGGAAATGAAAATGATCAAGTAGCTAGCGAAGGATCTGGTGT
TATCTATAGAAAAGATAAGGATTATGCTTACTTAGTTACCAATACACACGTTATCAATGGAGCAAAAAAAGTTGATATCC
GTCTGGCTGATGGGAATAAGGTTCCTGGTGAAATAGTCGGGACTGATACATATTCTGATATTTCTGTAGTCAGAATTCCT
GCTGATAAGGTTAAAAATGTAGCAGAATTTGGAGATTCTAGTAAATTAACCGTTGGAGAAACTGCCATTGCAATCGGAAG
CCCTCTTGGTTCTGATTATGCTAATACAGTGACTCAGGGAATTGTTTCTAGTCTAAGCCGTAATGTTTCTTCACGATCAG
AAGATGGTCAGACAATTGCTACCCAAGCTATTCAAACTGATGCAGCAATTAATCCAGGTAACTCTGGTGGTCCTCTTGTA
AACATTCAAGGTCAAGTTATTGGTATTACCTCTAGTAAAATTGCTAACACCAATAATGGTAGTACTTCTGTTGAGGGAAT
GGGATTTGCAATCCCATCCAATGATGTTGTAAGTATCATTGAACAATTAGAAAAGAATGGAAAAGTCATTCGACCAGCAT
TAGGAATTCAAATGGTCAACTTAAGTAGTTTATCTTCTTCAAGCTCTGATCGATTAAAACTTCCAGACAATATTAAGAAT
GGTGTCGTTGTTCGTTCCACACAAACTGGAATGCCTGCTGATGGTAAGTTAGAAAAATATGATGTGATTACAAAAATTGA
TGATACAGAAATATCATCTGCTAGTGATATCCAATCAGCTCTTTATAAACATTCGATTAATGAAGAAATAAAAGTTACTT
ATTACCGTGATGGAAAAGAGCAAACAACAACTATTAAACTAACTAAATCAACTGATGATTTAAGCTCTGAATAA

Domains

Predicted by InterproScan.

• Trypsin-like peptidase domain (Trypsin_2) (104-249)

• Peptidase family M50 (Peptidase_M50) (235-391)

• PDZ domain (PDZ_2) (292-387)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
htrA	Streptococcus gordonii str. Challis substr. CH1	98.237	100	0.982
htrA	Streptococcus mitis NCTC 12261	65.829	100	0.66
htrA	Streptococcus pneumoniae Rx1	65.909	99.748	0.657
htrA	Streptococcus pneumoniae D39	65.909	99.748	0.657
htrA	Streptococcus pneumoniae R6	65.909	99.748	0.657
htrA	Streptococcus pneumoniae TIGR4	65.909	99.748	0.657
htrA	Streptococcus mutans UA159	56.14	100	0.564