Detailed information    

insolico Bioinformatically predicted

Overview

Name   comD/comD1   Type   Regulator
Locus tag   DQM54_RS10775 Genome accession   NZ_LS483375
Coordinates   2150074..2151432 (-) Length   452 a.a.
NCBI ID   WP_111724324.1    Uniprot ID   -
Organism   Streptococcus gordonii strain NCTC3165     
Function   phosphorylation of ComE (predicted from homology)   
Competence regulation

Genomic Context

Location: 2145074..2156432
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DQM54_RS10750 (NCTC3165_02140) pth 2147231..2147800 (-) 570 WP_111724267.1 aminoacyl-tRNA hydrolase -
  DQM54_RS10755 (NCTC3165_02141) ychF 2147873..2148988 (-) 1116 WP_008808030.1 redox-regulated ATPase YchF -
  DQM54_RS10770 (NCTC3165_02144) comE/comE2 2149310..2150077 (-) 768 WP_008808031.1 competence system response regulator transcription factor ComE Regulator
  DQM54_RS10775 (NCTC3165_02145) comD/comD1 2150074..2151432 (-) 1359 WP_111724324.1 competence system sensor histidine kinase ComD Regulator
  DQM54_RS10780 (NCTC3165_02146) comC/comC1 2151448..2151612 (-) 165 WP_080998577.1 bacteriocin Regulator
  DQM54_RS10790 (NCTC3165_02148) rlmH 2151898..2152377 (-) 480 WP_008808034.1 23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH -
  DQM54_RS10795 (NCTC3165_02149) htrA 2152571..2153764 (+) 1194 WP_111724268.1 S1C family serine protease Regulator
  DQM54_RS10800 (NCTC3165_02150) spo0J 2153830..2154594 (+) 765 WP_111724269.1 ParB/RepB/Spo0J family partition protein Regulator

Sequence

Protein


Download         Length: 452 a.a.        Molecular weight: 52594.99 Da        Isoelectric Point: 5.5158

>NTDB_id=1139164 DQM54_RS10775 WP_111724324.1 2150074..2151432(-) (comD/comD1) [Streptococcus gordonii strain NCTC3165]
MNFEKIFAIFSLLVQTISFVTVYKKICDIKKLNISIIFLYLTISFSSLILAQFYNLLPEYGDVLSTFLHYLLIFFQPLIL
HLYFSKKGLYKGYVSIFLSLLIYLSVSSSETFFSVIISSVTGDDFVNQYWGSYYTIVNILALFFVLKSFEFFEFEFSYFK
NFDFEKEIMNVIKIYVTIHILLNISHWFSENAHLNSFASMIATIGFIMFLSTLFYLKSAREQYEKAKEIQQKKEEQRQLQ
LYTDEIVGLYNEIRGFRHDYAGMLTSLQTGINSGDMKEVERIFHNVLSQANISLRSDDYTFFELNNVQDTALRSVLIQTI
FKARECGVEIVFEMKDVIGTLPMKLLDLVRVASVLLNNAVEGAAESPSKTMNVSLVKLDKEIVFVIQNSRQSRYINLEEI
YEVGFSTKGENRGLGLNNVKEIIDKYDEVILETDIETNYFIQVVRFKRKEQI

Nucleotide


Download         Length: 1359 bp        

>NTDB_id=1139164 DQM54_RS10775 WP_111724324.1 2150074..2151432(-) (comD/comD1) [Streptococcus gordonii strain NCTC3165]
ATGAATTTTGAAAAAATATTTGCTATTTTCTCTTTACTAGTTCAAACAATTTCTTTTGTTACTGTATACAAAAAAATATG
TGATATAAAAAAATTAAATATTTCTATCATATTTCTGTACTTAACAATAAGTTTTAGTAGTTTGATATTAGCACAGTTTT
ATAATTTATTACCCGAATATGGAGATGTATTAAGTACTTTCTTACATTACTTACTTATATTTTTCCAACCACTAATCTTA
CATTTATATTTTTCTAAAAAAGGATTATATAAAGGATATGTATCTATCTTTTTATCCTTACTTATATATCTTTCTGTATC
ATCTTCTGAAACTTTTTTCTCAGTTATTATATCTTCAGTGACAGGAGATGATTTTGTTAATCAATACTGGGGTTCTTACT
ATACTATAGTAAATATCTTAGCATTATTTTTTGTTTTGAAATCTTTTGAATTTTTTGAGTTTGAATTTAGTTATTTTAAA
AATTTTGATTTTGAAAAAGAAATAATGAATGTAATTAAAATTTATGTAACGATTCATATCTTATTAAATATTTCTCATTG
GTTCAGCGAAAATGCACATCTTAATAGCTTTGCTAGTATGATTGCAACTATAGGATTTATTATGTTTTTGTCGACCTTAT
TTTATCTGAAGTCTGCTCGTGAACAATATGAAAAAGCTAAAGAAATTCAGCAAAAAAAGGAAGAACAAAGACAACTACAA
CTTTATACAGATGAAATTGTAGGTCTTTATAACGAAATTCGAGGTTTTCGTCATGATTATGCTGGTATGTTAACAAGTTT
ACAAACAGGAATTAACTCAGGTGATATGAAAGAAGTAGAGAGAATCTTTCATAATGTTTTAAGTCAAGCTAATATTTCCC
TTCGATCAGATGACTATACTTTTTTTGAGTTAAATAATGTTCAAGACACTGCCTTGAGAAGTGTGCTAATTCAAACTATA
TTTAAGGCTCGAGAGTGTGGAGTAGAGATCGTATTTGAAATGAAGGATGTTATTGGGACATTACCTATGAAACTTTTAGA
TTTAGTTCGAGTAGCTAGTGTATTGCTCAATAATGCGGTTGAAGGGGCAGCTGAAAGTCCCTCAAAAACAATGAACGTGT
CTTTAGTAAAGCTAGATAAAGAAATTGTTTTTGTAATTCAGAATTCTCGTCAAAGCCGTTATATTAATTTAGAAGAAATT
TATGAAGTAGGCTTCTCAACAAAAGGAGAAAATCGAGGATTAGGTTTAAATAATGTCAAAGAAATTATTGACAAATATGA
TGAAGTTATTCTGGAAACAGATATAGAAACAAATTATTTTATACAAGTTGTAAGATTTAAAAGAAAGGAACAAATATGA

Domains

Predicted by InterproScan.

GHKL domain (HATPase_c_5)

(343-444)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comD/comD1 Streptococcus gordonii str. Challis substr. CH1

76.6

100

0.768
  comD/comD2 Streptococcus gordonii strain NCTC7865

77.405

98.894

0.765
  comD/comD2 Streptococcus pneumoniae TIGR4

49.34

83.85

0.414
  comD/comD1 Streptococcus pneumoniae Rx1

49.077

83.85

0.412
  comD/comD1 Streptococcus pneumoniae D39

49.077

83.85

0.412
  comD/comD1 Streptococcus pneumoniae R6

49.077

83.85

0.412
  comD Streptococcus mitis NCTC 12261

48.285

83.85

0.405
  comD Streptococcus mitis SK321

48.404

83.186

0.403

Multiple sequence alignment