Detailed information NTG1139149

Bioinformatically predicted

Overview

• Name: comYD
• Type: Machinery gene
• Locus tag: DQM54_RS09555
• Genome accession: NZ_LS483375
• Coordinates: 1932540..1932968 (-)
• Length: 142 a.a.
• NCBI ID: WP_012130939.1
• Uniprot ID: A8AZH7
• Organism: Streptococcus gordonii strain NCTC3165
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1927540..1937968

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DQM54_RS09525 (NCTC3165_01894)	-	1928507..1929172 (-)	666	WP_111724177.1	CPBP family intramembrane glutamic endopeptidase	-
DQM54_RS09530 (NCTC3165_01895)	-	1929218..1930408 (-)	1191	WP_045634156.1	acetate kinase	-
DQM54_RS09535 (NCTC3165_01896)	comYH	1930458..1931411 (-)	954	WP_111724178.1	class I SAM-dependent methyltransferase	Machinery gene
DQM54_RS09540 (NCTC3165_01897)	comGG	1931442..1931870 (-)	429	WP_111724318.1	competence type IV pilus minor pilin ComGG	-
DQM54_RS09545 (NCTC3165_01898)	comGF/cglF	1931854..1932291 (-)	438	WP_111724179.1	competence type IV pilus minor pilin ComGF	Machinery gene
DQM54_RS09550 (NCTC3165_01899)	comGE/cglE	1932275..1932568 (-)	294	WP_111724180.1	competence type IV pilus minor pilin ComGE	Machinery gene
DQM54_RS09555 (NCTC3165_01900)	comYD	1932540..1932968 (-)	429	WP_012130939.1	competence type IV pilus minor pilin ComGD	Machinery gene
DQM54_RS09560 (NCTC3165_01901)	comYC	1932928..1933245 (-)	318	WP_012130940.1	competence type IV pilus major pilin ComGC	Machinery gene
DQM54_RS09565 (NCTC3165_01902)	comYB	1933242..1934276 (-)	1035	WP_111724181.1	competence type IV pilus assembly protein ComGB	Machinery gene
DQM54_RS09570 (NCTC3165_01903)	comYA	1934209..1935147 (-)	939	WP_111724182.1	competence type IV pilus ATPase ComGA	Machinery gene
DQM54_RS09575 (NCTC3165_01904)	-	1935250..1935618 (-)	369	WP_046164737.1	DUF1033 family protein	-

Sequence

Protein

• Length: 142 a.a.
• Molecular weight: 16043.65 Da
• Isoelectric Point: 10.1975

>NTDB_id=1139149 DQM54_RS09555 WP_012130939.1 1932540..1932968(-) (comYD) [Streptococcus gordonii strain NCTC3165]
MVRTIVRLRQLPIKAFTVLESLLVLMISSFILLALSSSVQATFEQIQAKIFFLEFEHFYQESQKLSVSSQRKLVLEISSQ
EISNGYARLPIPKGIQAPESTQIYFDKAGGNSSLSKVQFQTKEGLVTYQLYIGNGKFKKTTN

Nucleotide

• Length: 429 bp

>NTDB_id=1139149 DQM54_RS09555 WP_012130939.1 1932540..1932968(-) (comYD) [Streptococcus gordonii strain NCTC3165]
ATGGTAAGAACAATAGTGAGACTCAGGCAGTTGCCAATTAAGGCCTTTACAGTTTTGGAAAGCCTCTTGGTCTTGATGAT
TAGCAGTTTTATCTTGCTGGCTCTATCAAGTTCAGTTCAAGCTACATTTGAACAGATTCAGGCAAAGATCTTCTTTTTAG
AATTTGAGCATTTTTATCAGGAAAGTCAGAAGCTTAGCGTATCTTCTCAGAGAAAGCTAGTGCTAGAAATATCTAGTCAA
GAGATTTCAAACGGTTATGCTCGTCTTCCAATTCCCAAAGGAATCCAAGCGCCTGAATCTACACAGATCTATTTTGATAA
GGCTGGTGGTAATTCTTCACTCAGTAAAGTTCAGTTTCAAACCAAGGAAGGACTGGTGACCTATCAACTCTATATTGGAA
ATGGCAAATTTAAGAAAACGACAAATTAA

Domains

No domain identified.

3D structure

• AlphaFold DB: A8AZH7

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comYD	Streptococcus gordonii str. Challis substr. CH1	100	100	1
comGD/cglD	Streptococcus pneumoniae TIGR4	59.055	89.437	0.528
comGD/cglD	Streptococcus mitis SK321	59.055	89.437	0.528
comGD/cglD	Streptococcus pneumoniae Rx1	59.055	89.437	0.528
comGD/cglD	Streptococcus pneumoniae D39	59.055	89.437	0.528
comGD/cglD	Streptococcus pneumoniae R6	59.055	89.437	0.528
comGD/cglD	Streptococcus mitis NCTC 12261	55.97	94.366	0.528
comYD	Streptococcus mutans UA140	50.388	90.845	0.458
comYD	Streptococcus mutans UA159	50.388	90.845	0.458
comGD	Lactococcus lactis subsp. cremoris KW2	36.879	99.296	0.366