Detailed information    

insolico Bioinformatically predicted

Overview

Name   dprA   Type   Machinery gene
Locus tag   DQM60_RS04540 Genome accession   NZ_LS483366
Coordinates   1016689..1017528 (+) Length   279 a.a.
NCBI ID   WP_070847319.1    Uniprot ID   -
Organism   Streptococcus salivarius strain NCTC7366     
Function   ssDNA binding; loading RecA onto ssDNA (predicted from homology)   
DNA processing

Genomic Context

Location: 1011689..1022528
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DQM60_RS04510 (NCTC7366_00910) - 1012107..1012634 (+) 528 WP_049553742.1 ECF transporter S component -
  DQM60_RS04515 (NCTC7366_00911) - 1012657..1013169 (+) 513 WP_049553741.1 transcription repressor NadR -
  DQM60_RS04520 (NCTC7366_00912) - 1013267..1013956 (+) 690 WP_049553740.1 XRE family transcriptional regulator -
  DQM60_RS04525 (NCTC7366_00913) ylqF 1014085..1014939 (+) 855 WP_014634567.1 ribosome biogenesis GTPase YlqF -
  DQM60_RS04530 (NCTC7366_00914) - 1014926..1015696 (+) 771 WP_084871341.1 ribonuclease HII -
  DQM60_RS04535 (NCTC7366_00915) - 1015703..1016623 (+) 921 WP_049553738.1 ROK family protein -
  DQM60_RS04540 (NCTC7366_00916) dprA 1016689..1017528 (+) 840 WP_070847319.1 DNA-processing protein DprA Machinery gene
  DQM60_RS04545 (NCTC7366_00917) topA 1017696..1019840 (+) 2145 WP_004182436.1 type I DNA topoisomerase -
  DQM60_RS04550 (NCTC7366_00918) - 1020023..1020697 (+) 675 WP_004182437.1 ABC transporter ATP-binding protein -
  DQM60_RS04555 (NCTC7366_00919) - 1020702..1021430 (+) 729 WP_229039796.1 lantibiotic ABC transporter permease -

Sequence

Protein


Download         Length: 279 a.a.        Molecular weight: 31260.17 Da        Isoelectric Point: 8.4513

>NTDB_id=1138779 DQM60_RS04540 WP_070847319.1 1016689..1017528(+) (dprA) [Streptococcus salivarius strain NCTC7366]
MNNFELFKLKAAGLTNLNILNILDYQKTQDRKLSLRDMAVVSKSKNAVLFMEKYKSLDIKQLKEQFDHFPTLSIFDKEYP
IELKHTYNPPVLLYYQGNLDLLSKPKLAVVGARKCSETGKQSVRKIVSELGNHFTIVSGLARGIDTCAHMEALKNKGNTI
AVIGTGLDVYYPKENKALQDYMAKNHLVLTEYGPGEQPLKYHFPERNRIISGLCQGVMVVEAKLRSGSLITCERAMEEGR
DVFAIPGNILDGKSDGCHHLIQEGAKCITTGFDILSEFS

Nucleotide


Download         Length: 840 bp        

>NTDB_id=1138779 DQM60_RS04540 WP_070847319.1 1016689..1017528(+) (dprA) [Streptococcus salivarius strain NCTC7366]
ATGAATAATTTTGAACTTTTTAAACTTAAAGCCGCTGGGTTGACGAATTTAAATATCTTAAATATTTTGGACTATCAAAA
GACTCAAGATAGAAAATTGAGTTTACGTGATATGGCAGTGGTATCCAAGTCTAAAAATGCCGTTCTTTTTATGGAAAAAT
ACAAGAGTTTAGATATTAAGCAACTCAAAGAACAATTCGACCATTTTCCTACGTTATCGATTTTTGATAAAGAATATCCC
ATTGAGCTGAAGCATACCTATAATCCTCCTGTCCTCCTTTATTATCAGGGGAATCTTGATTTACTGAGTAAACCAAAGCT
AGCTGTTGTTGGGGCAAGAAAGTGTTCTGAAACAGGCAAACAGTCTGTCCGTAAAATTGTTAGTGAACTTGGGAATCACT
TTACTATTGTGAGTGGATTGGCGCGTGGGATTGATACTTGTGCGCATATGGAGGCCTTGAAAAATAAGGGAAACACTATT
GCAGTTATCGGGACAGGACTTGATGTTTATTATCCTAAAGAAAATAAAGCTTTGCAGGACTATATGGCCAAAAATCATTT
AGTTCTTACAGAATATGGACCAGGTGAGCAGCCTCTCAAGTACCACTTTCCTGAACGCAATCGGATTATTTCTGGATTGT
GTCAAGGAGTTATGGTTGTAGAAGCTAAGCTTCGCTCAGGAAGTCTGATTACTTGTGAGCGTGCCATGGAAGAAGGTAGA
GATGTTTTTGCTATTCCAGGAAATATTTTAGATGGAAAGTCAGATGGATGCCATCACTTAATTCAGGAGGGTGCAAAGTG
CATTACGACAGGGTTTGACATCCTTTCAGAGTTTTCTTGA

Domains

Predicted by InterproScan.

DNA processing protein A sterile alpha motif domain (SAM_DprA)

(1-62)

DNA recombination-mediator protein A (DNA_processg_A)

(71-269)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  dprA Streptococcus mutans UA159

71.685

100

0.717
  dprA/cilB/dalA Streptococcus pneumoniae Rx1

63.309

99.642

0.631
  dprA/cilB/dalA Streptococcus pneumoniae D39

63.309

99.642

0.631
  dprA/cilB/dalA Streptococcus pneumoniae R6

63.309

99.642

0.631
  dprA/cilB/dalA Streptococcus pneumoniae TIGR4

63.309

99.642

0.631
  dprA/cilB/dalA Streptococcus mitis SK321

63.309

99.642

0.631
  dprA/cilB/dalA Streptococcus mitis NCTC 12261

62.95

99.642

0.627
  dprA Lactococcus lactis subsp. cremoris KW2

59.712

99.642

0.595
  dprA Latilactobacillus sakei subsp. sakei 23K

40.613

93.548

0.38
  dprA Acinetobacter baumannii D1279779

45.133

81.004

0.366
  dprA Acinetobacter baumannii strain A118

45.133

81.004

0.366
  dprA Bacillus subtilis subsp. subtilis str. 168

48.095

75.269

0.362

Multiple sequence alignment