Detailed information    

insolico Bioinformatically predicted

Overview

Name   cinA   Type   Machinery gene
Locus tag   DQM48_RS09645 Genome accession   NZ_LS483348
Coordinates   1883522..1884781 (-) Length   419 a.a.
NCBI ID   WP_020917595.1    Uniprot ID   A0AB33AP19
Organism   Streptococcus lutetiensis strain NCTC8738     
Function   facilitate localization of RecA (predicted from homology)   
Homologous recombination

Genomic Context

Location: 1878522..1889781
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DQM48_RS09615 (NCTC8738_02031) - 1878572..1880146 (-) 1575 WP_058814325.1 hypothetical protein -
  DQM48_RS10655 (NCTC8738_02032) - 1880189..1880317 (-) 129 WP_260665378.1 hypothetical protein -
  DQM48_RS09620 (NCTC8738_02033) - 1880443..1880760 (-) 318 WP_020917592.1 DUF1292 domain-containing protein -
  DQM48_RS09625 (NCTC8738_02034) ruvX 1880793..1881212 (-) 420 WP_020917593.1 Holliday junction resolvase RuvX -
  DQM48_RS09630 (NCTC8738_02035) - 1881209..1881478 (-) 270 WP_003066890.1 IreB family regulatory phosphoprotein -
  DQM48_RS09635 (NCTC8738_02036) spx 1881725..1882123 (-) 399 WP_004233512.1 transcriptional regulator Spx -
  DQM48_RS09640 (NCTC8738_02037) recA 1882321..1883475 (-) 1155 WP_020917594.1 recombinase RecA Machinery gene
  DQM48_RS09645 (NCTC8738_02038) cinA 1883522..1884781 (-) 1260 WP_020917595.1 competence/damage-inducible protein A Machinery gene
  DQM48_RS09650 (NCTC8738_02039) - 1884910..1885803 (-) 894 WP_230318142.1 MFS transporter -
  DQM48_RS10600 (NCTC8738_02040) - 1885865..1886092 (-) 228 WP_228380500.1 MFS transporter -
  DQM48_RS09655 (NCTC8738_02041) - 1886293..1886844 (-) 552 WP_043895144.1 DNA-3-methyladenine glycosylase I -
  DQM48_RS09660 (NCTC8738_02042) ruvA 1886874..1887467 (-) 594 WP_020917597.1 Holliday junction branch migration protein RuvA -
  DQM48_RS09665 (NCTC8738_02043) mutL 1887468..1889408 (-) 1941 WP_020917598.1 DNA mismatch repair endonuclease MutL -

Sequence

Protein


Download         Length: 419 a.a.        Molecular weight: 45965.45 Da        Isoelectric Point: 5.5094

>NTDB_id=1137846 DQM48_RS09645 WP_020917595.1 1883522..1884781(-) (cinA) [Streptococcus lutetiensis strain NCTC8738]
MKAEIIAVGTEILTGQITNTNAQFLSEEFAKLGIDVFFQTAVGDNEERLLSIIDLASKRSDLVVLCGGLGPTEDDLTKQT
LAKYLGRNLVFDEQASKRLNEFFATRPQFTRTANNERQAQLIEGSTPLQNRTGLAVGGVIEVDGVTYVVLPGPPSELKPM
VWDYLVPLLSSDHKQLYSRVLRFFGIGESQLVTVLSDLIDNQTDPTIAPYAKIGEVTLRLSTKADDIESAKEKLDQLEQK
ILSKKTLNSIPLENLLYGYGDDNSMARVVFDLLKKKHKTITAAESLTAGLFQSSIADFSGSSSVFNGGFVTYSIEEKSKM
LQIPLEKLQEHGVVSHFTAEKMAEQSRKLTDADFGIGLTGVAGPDSLEGHPAGTVFIGIATREKVHSIRVLIGGRRRSDV
RHIACLYAFNLVRQALLQD

Nucleotide


Download         Length: 1260 bp        

>NTDB_id=1137846 DQM48_RS09645 WP_020917595.1 1883522..1884781(-) (cinA) [Streptococcus lutetiensis strain NCTC8738]
ATGAAAGCTGAGATTATCGCTGTAGGAACAGAGATTTTAACAGGACAAATCACAAATACCAATGCGCAATTTTTATCTGA
AGAATTTGCCAAGTTAGGGATTGATGTTTTTTTCCAAACAGCTGTTGGGGACAATGAAGAGCGTCTTTTGTCTATCATTG
ATTTGGCAAGTAAGCGTAGCGATTTAGTTGTTCTCTGTGGTGGTTTAGGACCAACTGAGGATGATTTGACAAAGCAAACC
TTAGCAAAATATTTAGGGCGTAACCTGGTCTTTGATGAACAGGCAAGTAAACGTCTAAATGAGTTCTTTGCGACACGTCC
TCAATTTACAAGAACAGCTAACAATGAACGCCAAGCTCAACTGATTGAAGGTTCAACTCCTTTGCAAAATAGGACTGGTT
TGGCTGTAGGTGGAGTGATTGAAGTTGACGGCGTCACTTATGTTGTTCTTCCTGGCCCACCAAGTGAGCTTAAGCCCATG
GTCTGGGATTATTTAGTGCCTTTGTTATCTAGCGACCATAAGCAACTTTATTCACGTGTTTTGCGTTTCTTTGGCATTGG
AGAAAGCCAACTGGTAACTGTTTTATCAGATTTGATTGACAACCAAACTGATCCAACCATTGCGCCATATGCTAAGATAG
GTGAAGTAACGCTGCGTTTGTCAACGAAAGCAGACGACATTGAATCAGCTAAGGAAAAACTAGACCAGCTAGAGCAAAAA
ATTCTTTCTAAGAAGACTTTAAATAGCATTCCGCTTGAGAATTTGCTTTATGGTTACGGTGATGACAATAGTATGGCGCG
TGTTGTTTTTGATTTGCTTAAGAAAAAACACAAGACCATTACAGCTGCAGAAAGTTTAACAGCAGGGCTATTTCAATCAA
GTATTGCAGACTTCTCAGGCTCTTCATCAGTCTTTAATGGTGGTTTTGTGACTTATAGCATTGAAGAAAAATCAAAAATG
CTTCAGATTCCATTAGAAAAGTTGCAAGAACACGGGGTTGTTAGTCACTTTACAGCTGAGAAAATGGCTGAGCAATCTCG
CAAGTTAACAGATGCTGATTTTGGGATTGGATTGACAGGAGTTGCAGGACCAGATAGCTTAGAAGGTCACCCAGCAGGAA
CAGTTTTCATTGGTATTGCTACTAGAGAAAAAGTTCATTCTATTCGTGTTCTCATAGGTGGACGAAGACGTTCAGACGTG
CGTCATATTGCATGTTTGTATGCTTTTAACTTGGTACGTCAAGCTTTATTACAGGATTAA

Domains

Predicted by InterproScan.

Probable molybdopterin binding domain (MoCF_biosynth)

(5-169)

Competence-damaged protein (CinA)

(263-415)

Damage-inducible protein CinA KH domain (CinA_KH)

(178-242)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  cinA Streptococcus mitis SK321

71.36

100

0.714
  cinA Streptococcus mutans UA159

71.463

99.523

0.711
  cinA Streptococcus mitis NCTC 12261

70.406

100

0.704
  cinA Streptococcus pneumoniae Rx1

69.451

100

0.695
  cinA Streptococcus pneumoniae TIGR4

69.451

100

0.695
  cinA Streptococcus pneumoniae R6

69.451

100

0.695
  cinA Streptococcus pneumoniae D39

69.212

100

0.692
  cinA Streptococcus suis isolate S10

54.327

99.284

0.539
  cinA Bacillus subtilis subsp. subtilis str. 168

45.735

100

0.461

Multiple sequence alignment