Detailed information    

insolico Bioinformatically predicted

Overview

Name   cinA   Type   Machinery gene
Locus tag   DQM73_RS00675 Genome accession   NZ_LS483346
Coordinates   117941..119197 (+) Length   418 a.a.
NCBI ID   WP_032908257.1    Uniprot ID   -
Organism   Streptococcus sanguinis strain NCTC11085     
Function   facilitate localization of RecA (predicted from homology)   
Homologous recombination

Genomic Context

Location: 112941..124197
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DQM73_RS00635 (NCTC11085_00122) - 113442..113963 (-) 522 WP_002926371.1 RDD family protein -
  DQM73_RS00640 (NCTC11085_00123) - 113947..114453 (-) 507 WP_002908492.1 helix-turn-helix domain-containing protein -
  DQM73_RS00645 (NCTC11085_00124) ruvA 114623..115213 (+) 591 WP_032908259.1 Holliday junction branch migration protein RuvA -
  DQM73_RS00650 (NCTC11085_00125) - 115224..115796 (+) 573 WP_002908494.1 DNA-3-methyladenine glycosylase I -
  DQM73_RS00655 (NCTC11085_00126) - 115806..116654 (-) 849 WP_002926370.1 helix-turn-helix domain-containing protein -
  DQM73_RS00665 (NCTC11085_00128) - 117253..117531 (+) 279 WP_223310420.1 bacteriocin immunity protein -
  DQM73_RS00675 (NCTC11085_00129) cinA 117941..119197 (+) 1257 WP_032908257.1 competence/damage-inducible protein A Machinery gene
  DQM73_RS00680 (NCTC11085_00130) recA 119255..120403 (+) 1149 WP_002894079.1 recombinase RecA Machinery gene
  DQM73_RS00685 (NCTC11085_00131) spx 120489..120887 (+) 399 WP_002894078.1 transcriptional regulator Spx -
  DQM73_RS00690 (NCTC11085_00132) - 121023..121595 (+) 573 WP_002926368.1 SP0191 family lipoprotein -
  DQM73_RS00695 (NCTC11085_00133) - 121701..122243 (+) 543 WP_002907743.1 hypothetical protein -
  DQM73_RS00700 (NCTC11085_00134) - 122421..122687 (+) 267 WP_002894075.1 IreB family regulatory phosphoprotein -
  DQM73_RS00705 (NCTC11085_00135) ruvX 122687..123106 (+) 420 WP_002894074.1 Holliday junction resolvase RuvX -
  DQM73_RS00710 (NCTC11085_00136) - 123131..123442 (+) 312 WP_002894073.1 DUF1292 domain-containing protein -

Sequence

Protein


Download         Length: 418 a.a.        Molecular weight: 44888.98 Da        Isoelectric Point: 4.5700

>NTDB_id=1137674 DQM73_RS00675 WP_032908257.1 117941..119197(+) (cinA) [Streptococcus sanguinis strain NCTC11085]
MKAEIIAVGTEILTGQIVNTNAQFLSEKLASLGIDVYFQTAVGDNENRLLSVLEIAQGRNNLIILTGGLGPTEDDLTKQT
LAKFLGRELIFDSQAVEKLDRFFASRPDYARTPNNERQAQLVEGSTPLPNATGLAVGGLLEADGVTYVVLPGPPSELKPM
VNNELVPLLSTGQKLYSRVLRFFGIGESQLVTILSEMIEQQSDPTIAPYAKTGEVTLRLSTKALSQVEADTKFEAVEKEI
LEHKTFEGQPLSEIFYGYGDDNSLAQVAFELLKSQGKTISAAESLTAGLFQATLADFAGASSIFSGGFVTYSMEEKSRML
DIPLGDLEEHGVVSAFTAGKMAEQARKLTESDLAVSLTGVAGPDSLEDHPAGTVFIGLASASGTETIKVNIAGRSRRDVR
KIAVLHAFNLVRKTLLNS

Nucleotide


Download         Length: 1257 bp        

>NTDB_id=1137674 DQM73_RS00675 WP_032908257.1 117941..119197(+) (cinA) [Streptococcus sanguinis strain NCTC11085]
ATGAAAGCAGAAATTATTGCTGTGGGCACTGAGATTCTGACGGGTCAGATTGTCAATACCAATGCCCAATTTTTATCTGA
AAAACTTGCGAGTCTGGGGATTGATGTTTATTTTCAGACAGCAGTAGGGGACAATGAAAATCGTCTCCTATCTGTTTTGG
AAATTGCTCAAGGGCGCAATAATCTGATTATCCTAACAGGAGGCTTGGGGCCAACAGAGGATGATTTGACCAAGCAGACC
TTGGCTAAGTTCTTAGGACGTGAGCTCATTTTTGACTCACAGGCTGTGGAAAAGCTGGATCGCTTTTTTGCTAGCCGGCC
AGATTATGCTCGAACGCCCAATAATGAGCGTCAGGCCCAGCTGGTCGAAGGTTCGACTCCGTTACCAAATGCGACCGGCT
TAGCTGTTGGAGGATTGTTAGAAGCAGACGGAGTGACCTATGTAGTCCTGCCTGGCCCGCCTAGTGAGCTTAAGCCTATG
GTTAATAATGAGTTGGTTCCCCTCTTATCCACAGGCCAGAAATTATATTCACGGGTGCTGCGTTTCTTTGGTATCGGCGA
GAGTCAGCTAGTGACTATTTTGTCAGAGATGATTGAGCAGCAGAGTGACCCCACCATTGCTCCTTATGCAAAGACGGGAG
AGGTTACCCTGCGACTGTCCACCAAGGCTCTGAGTCAGGTAGAAGCTGACACCAAGTTTGAGGCTGTGGAAAAGGAAATT
TTGGAACATAAGACTTTTGAGGGACAGCCCTTGTCAGAGATTTTCTATGGTTACGGGGATGACAATTCCTTGGCACAGGT
GGCTTTTGAGTTGCTGAAGAGTCAAGGGAAGACGATTTCGGCGGCGGAGAGTCTGACAGCAGGCCTCTTTCAAGCGACCT
TGGCTGATTTTGCTGGAGCCTCTTCCATTTTTTCAGGTGGCTTTGTCACCTACAGCATGGAGGAAAAGAGCCGGATGCTG
GATATTCCGTTGGGAGACTTGGAGGAGCATGGAGTTGTTTCAGCTTTTACGGCAGGGAAAATGGCAGAGCAGGCTAGAAA
GCTGACCGAAAGCGACTTAGCTGTCAGTTTGACAGGTGTGGCAGGCCCAGATTCACTGGAAGATCATCCTGCAGGGACCG
TTTTTATCGGTTTAGCTAGTGCTTCAGGAACGGAAACTATTAAGGTCAATATTGCTGGACGCAGTCGTCGTGATGTGCGG
AAAATTGCTGTTCTGCACGCCTTCAACCTAGTACGAAAAACTTTATTAAATAGCTGA

Domains

Predicted by InterproScan.

Probable molybdopterin binding domain (MoCF_biosynth)

(5-169)

Damage-inducible protein CinA KH domain (CinA_KH)

(177-241)

Competence-damaged protein (CinA)

(262-415)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  cinA Streptococcus mitis SK321

78.177

99.761

0.78
  cinA Streptococcus mitis NCTC 12261

77.698

99.761

0.775
  cinA Streptococcus pneumoniae TIGR4

76.978

99.761

0.768
  cinA Streptococcus pneumoniae Rx1

76.978

99.761

0.768
  cinA Streptococcus pneumoniae R6

76.978

99.761

0.768
  cinA Streptococcus pneumoniae D39

76.739

99.761

0.766
  cinA Streptococcus mutans UA159

74.88

100

0.749
  cinA Streptococcus suis isolate S10

55.288

99.522

0.55
  cinA Bacillus subtilis subsp. subtilis str. 168

46.651

100

0.467

Multiple sequence alignment