Detailed information    

insolico Bioinformatically predicted

Overview

Name   vicR   Type   Regulator
Locus tag   DQL21_RS03395 Genome accession   NZ_LS483343
Coordinates   646923..647630 (+) Length   235 a.a.
NCBI ID   WP_018029528.1    Uniprot ID   -
Organism   Streptococcus ferus strain NCTC12278     
Function   repress comCDE expression; repress comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 641923..652630
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DQL21_RS03365 (NCTC12278_00660) - 642545..642733 (+) 189 WP_018029522.1 DNA-directed RNA polymerase subunit beta -
  DQL21_RS03370 (NCTC12278_00661) endA 642774..643652 (+) 879 WP_018029523.1 DNA/RNA non-specific endonuclease Machinery gene
  DQL21_RS03375 (NCTC12278_00662) - 643686..644336 (-) 651 WP_018029524.1 amino acid ABC transporter permease -
  DQL21_RS03380 (NCTC12278_00663) - 644351..645055 (-) 705 WP_018029525.1 amino acid ABC transporter permease -
  DQL21_RS03385 (NCTC12278_00664) - 645073..645888 (-) 816 WP_018029526.1 transporter substrate-binding domain-containing protein -
  DQL21_RS03390 (NCTC12278_00665) - 645885..646667 (-) 783 WP_018029527.1 amino acid ABC transporter ATP-binding protein -
  DQL21_RS03395 (NCTC12278_00666) vicR 646923..647630 (+) 708 WP_018029528.1 response regulator YycF Regulator
  DQL21_RS03400 (NCTC12278_00667) vicK 647623..648972 (+) 1350 WP_018029529.1 cell wall metabolism sensor histidine kinase VicK Regulator
  DQL21_RS03405 (NCTC12278_00668) vicX 648974..649777 (+) 804 WP_018029530.1 MBL fold metallo-hydrolase Regulator
  DQL21_RS03410 (NCTC12278_00669) rnc 649880..650575 (+) 696 WP_018029531.1 ribonuclease III -

Sequence

Protein


Download         Length: 235 a.a.        Molecular weight: 26864.62 Da        Isoelectric Point: 4.7030

>NTDB_id=1137593 DQL21_RS03395 WP_018029528.1 646923..647630(+) (vicR) [Streptococcus ferus strain NCTC12278]
MKKILIVDDEKPISDIIKFNLSKEGYDTITAFDGREALACFEEENPDLIILDLMLPELDGLEVAKEVRKTSHVPIIMLSA
KDSEFDKVIGLEIGADDYVTKPFSNRELLARVKAHLRRTENIETAVAEENAGGTSELVIGELQILPDAFIAKKRGEEVEL
THREFELLHHLATHTGQVMTREHLLETVWGYDYFGDVRTVDVTVRRLREKIEDTPSRPEYILTRRGVGYYMKSYD

Nucleotide


Download         Length: 708 bp        

>NTDB_id=1137593 DQL21_RS03395 WP_018029528.1 646923..647630(+) (vicR) [Streptococcus ferus strain NCTC12278]
ATGAAAAAAATTCTTATTGTTGATGATGAAAAACCCATCTCGGATATTATCAAATTTAATCTAAGTAAGGAAGGCTATGA
CACCATAACTGCTTTTGATGGTCGTGAAGCTTTGGCCTGCTTTGAGGAAGAAAATCCTGATTTAATCATTCTGGACTTGA
TGCTACCAGAGCTGGACGGTCTGGAAGTCGCTAAGGAAGTACGCAAAACCAGTCATGTACCGATTATCATGCTTTCTGCC
AAGGATAGTGAGTTTGATAAAGTTATTGGCCTTGAGATTGGGGCAGACGATTATGTGACTAAACCTTTTTCGAATCGTGA
ACTACTAGCGCGTGTCAAGGCTCATCTTCGCCGTACCGAAAATATTGAGACGGCAGTTGCGGAAGAAAATGCCGGCGGTA
CCTCAGAGCTGGTTATCGGAGAGCTTCAGATTCTGCCGGATGCTTTTATTGCCAAAAAGCGTGGAGAAGAAGTCGAGCTG
ACCCATCGTGAGTTTGAATTGCTCCATCATTTAGCGACTCATACAGGACAGGTGATGACTCGCGAACACCTGCTTGAAAC
CGTTTGGGGTTATGACTACTTTGGAGATGTACGGACAGTTGACGTAACCGTACGCCGTTTACGTGAAAAAATTGAGGATA
CTCCATCTCGTCCAGAATATATTTTGACAAGACGCGGTGTCGGTTATTACATGAAATCCTATGACTAA

Domains

Predicted by InterproScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(155-230)

Response regulator receiver domain (Response_reg)

(4-113)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vicR Streptococcus mutans UA159

94.043

100

0.94
  micA Streptococcus pneumoniae Cp1015

78.112

99.149

0.774
  covR Lactococcus lactis subsp. lactis strain DGCC12653

47.436

99.574

0.472
  covR Streptococcus salivarius strain HSISS4

44.589

98.298

0.438
  scnR Streptococcus mutans UA159

38.034

99.574

0.379

Multiple sequence alignment