Detailed information    

insolico Bioinformatically predicted

Overview

Name   vicK   Type   Regulator
Locus tag   DQL21_RS03400 Genome accession   NZ_LS483343
Coordinates   647623..648972 (+) Length   449 a.a.
NCBI ID   WP_018029529.1    Uniprot ID   -
Organism   Streptococcus ferus strain NCTC12278     
Function   repress comCDE expression; repress comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 642623..653972
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DQL21_RS03370 (NCTC12278_00661) endA 642774..643652 (+) 879 WP_018029523.1 DNA/RNA non-specific endonuclease Machinery gene
  DQL21_RS03375 (NCTC12278_00662) - 643686..644336 (-) 651 WP_018029524.1 amino acid ABC transporter permease -
  DQL21_RS03380 (NCTC12278_00663) - 644351..645055 (-) 705 WP_018029525.1 amino acid ABC transporter permease -
  DQL21_RS03385 (NCTC12278_00664) - 645073..645888 (-) 816 WP_018029526.1 transporter substrate-binding domain-containing protein -
  DQL21_RS03390 (NCTC12278_00665) - 645885..646667 (-) 783 WP_018029527.1 amino acid ABC transporter ATP-binding protein -
  DQL21_RS03395 (NCTC12278_00666) vicR 646923..647630 (+) 708 WP_018029528.1 response regulator YycF Regulator
  DQL21_RS03400 (NCTC12278_00667) vicK 647623..648972 (+) 1350 WP_018029529.1 cell wall metabolism sensor histidine kinase VicK Regulator
  DQL21_RS03405 (NCTC12278_00668) vicX 648974..649777 (+) 804 WP_018029530.1 MBL fold metallo-hydrolase Regulator
  DQL21_RS03410 (NCTC12278_00669) rnc 649880..650575 (+) 696 WP_018029531.1 ribonuclease III -

Sequence

Protein


Download         Length: 449 a.a.        Molecular weight: 51622.71 Da        Isoelectric Point: 4.6318

>NTDB_id=1137594 DQL21_RS03400 WP_018029529.1 647623..648972(+) (vicK) [Streptococcus ferus strain NCTC12278]
MTNFFSTTPFLLRLVFGGLLFLLFLYFIFLNYREYKNNKQIKAINKKVRSLIAGDYSDKLDIKSNPELTDLVNNINDLSE
VFRLTHENLAQETNRLTNVLTYMTDGVLATDRQGKIVLINDTAQKQLNISREEALEMSILDFLEEDSYSLNDLIAQKPEL
IWYQRDENDEFITLRVRFALNRRESGFISGLIAVLHDVTEQEKEERERRLFVSNVSHELRTPLTSVKSYLEALDDGALTE
AVAPSFIKVSLDETNRMMRMISDLLNLSRIDNENSPLNVELINFTAFMTYILNRFDQIQTQNSLAGKVYEIIRDYPLRPV
WVEIDTDKMTQVVDNIMNNAIKYSPDGGKITVNMNTTDTQLIISISDQGLGIPKKDLPLIFDRFYRVDKARSRAQGGTGL
GLAITKEIIKQHGGFIWAKSDYGKGSTFTIVLPYDRDNILDDEWEEEEA

Nucleotide


Download         Length: 1350 bp        

>NTDB_id=1137594 DQL21_RS03400 WP_018029529.1 647623..648972(+) (vicK) [Streptococcus ferus strain NCTC12278]
ATGACTAATTTTTTTTCAACAACGCCCTTCCTGCTGAGGCTGGTTTTTGGAGGGCTTTTATTCCTTTTATTTCTCTATTT
TATCTTTTTGAATTATCGAGAATATAAGAATAATAAACAAATCAAAGCCATTAATAAAAAAGTCAGATCTCTGATTGCGG
GCGATTATTCAGATAAATTAGATATTAAATCAAATCCAGAGTTGACCGATTTGGTGAACAATATCAATGATTTATCAGAA
GTTTTTCGTCTGACGCATGAAAATTTGGCTCAAGAGACCAACCGTCTGACCAATGTCTTGACCTACATGACAGATGGGGT
TTTGGCGACTGATCGGCAAGGGAAAATTGTCCTGATTAACGACACTGCTCAAAAGCAGCTGAATATCAGCCGAGAAGAGG
CCTTGGAGATGTCTATCCTTGATTTTTTGGAAGAGGATAGTTATAGTTTAAATGATTTAATTGCCCAAAAGCCAGAGCTG
ATCTGGTATCAGCGCGATGAAAATGATGAGTTCATCACCCTTCGGGTAAGGTTTGCTTTAAATCGCCGGGAAAGTGGCTT
TATTTCAGGTTTGATTGCTGTTTTGCACGATGTGACAGAGCAGGAGAAGGAAGAAAGAGAGCGGCGCTTGTTTGTATCCA
ATGTCAGCCATGAGCTGAGAACGCCGCTGACCTCGGTTAAGTCCTACTTGGAAGCCTTAGATGATGGCGCTCTGACAGAG
GCCGTTGCTCCGAGTTTTATCAAGGTTTCCTTAGATGAGACCAATCGGATGATGCGGATGATTTCAGATTTGCTGAATCT
TTCTCGGATTGATAATGAAAATAGTCCTTTGAATGTCGAATTGATTAACTTTACAGCCTTTATGACCTATATTCTCAATC
GCTTCGATCAGATTCAGACGCAGAATTCTTTGGCGGGCAAGGTTTATGAGATTATCCGCGATTATCCTCTTCGACCGGTC
TGGGTGGAAATTGATACGGATAAGATGACTCAAGTGGTTGATAATATCATGAATAACGCCATCAAGTATTCGCCAGATGG
CGGTAAAATAACGGTTAATATGAACACGACGGATACCCAGTTGATTATTTCCATTTCAGATCAGGGCCTGGGAATTCCTA
AAAAAGATTTACCGTTAATTTTTGATCGTTTTTATCGGGTTGATAAAGCCAGAAGCCGGGCACAAGGCGGGACAGGGCTG
GGGCTGGCTATTACAAAAGAAATTATTAAACAGCATGGCGGTTTTATTTGGGCTAAGAGTGACTACGGTAAGGGATCGAC
CTTTACTATTGTCTTGCCTTACGACCGTGACAATATCTTAGATGATGAATGGGAGGAAGAAGAAGCATAG

Domains

Predicted by InterproScan.

PAS fold (PAS)

(102-179)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(325-435)

His Kinase A (phospho-acceptor) domain (HisKA)

(208-272)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vicK Streptococcus mutans UA159

78.311

97.55

0.764
  micB Streptococcus pneumoniae Cp1015

68.664

96.659

0.664

Multiple sequence alignment