Detailed information    

insolico Bioinformatically predicted

Overview

Name   cinA   Type   Machinery gene
Locus tag   DQL23_RS10290 Genome accession   NZ_LS483341
Coordinates   2111714..2112970 (-) Length   418 a.a.
NCBI ID   WP_060554240.1    Uniprot ID   -
Organism   Streptococcus gordonii strain NCTC7865     
Function   facilitate localization of RecA (predicted from homology)   
Homologous recombination

Genomic Context

Location: 2106714..2117970
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DQL23_RS10260 (NCTC7865_02071) - 2108172..2108483 (-) 312 WP_008809966.1 DUF1292 domain-containing protein -
  DQL23_RS10265 (NCTC7865_02072) ruvX 2108504..2108923 (-) 420 WP_012131012.1 Holliday junction resolvase RuvX -
  DQL23_RS10270 (NCTC7865_02073) - 2108923..2109189 (-) 267 WP_008809968.1 IreB family regulatory phosphoprotein -
  DQL23_RS10275 (NCTC7865_02074) - 2109301..2109873 (-) 573 WP_060554238.1 SP0191 family lipoprotein -
  DQL23_RS10280 (NCTC7865_02075) spx 2110019..2110417 (-) 399 WP_008809970.1 transcriptional regulator Spx -
  DQL23_RS10285 (NCTC7865_02076) recA 2110504..2111655 (-) 1152 WP_060554239.1 recombinase RecA Machinery gene
  DQL23_RS10290 (NCTC7865_02077) cinA 2111714..2112970 (-) 1257 WP_060554240.1 competence/damage-inducible protein A Machinery gene
  DQL23_RS10300 (NCTC7865_02078) - 2113240..2113650 (+) 411 WP_060554241.1 helix-turn-helix domain-containing protein -
  DQL23_RS10305 (NCTC7865_02079) - 2113701..2114360 (-) 660 WP_060554242.1 CPBP family intramembrane glutamic endopeptidase -
  DQL23_RS10310 (NCTC7865_02080) - 2114365..2114919 (-) 555 WP_060554243.1 DNA-3-methyladenine glycosylase I -
  DQL23_RS10315 (NCTC7865_02081) ruvA 2114929..2115522 (-) 594 WP_060554244.1 Holliday junction branch migration protein RuvA -
  DQL23_RS10320 (NCTC7865_02082) - 2115692..2116195 (+) 504 WP_060554245.1 helix-turn-helix domain-containing protein -
  DQL23_RS10325 (NCTC7865_02083) - 2116179..2116700 (+) 522 WP_060554246.1 RDD family protein -

Sequence

Protein


Download         Length: 418 a.a.        Molecular weight: 44674.76 Da        Isoelectric Point: 4.6073

>NTDB_id=1137509 DQL23_RS10290 WP_060554240.1 2111714..2112970(-) (cinA) [Streptococcus gordonii strain NCTC7865]
MKAEIIAVGTEILTGQIVNTNAQFLSEKLASLGIDVYFQTAVGDNENRLLSILEIAKGRSNLIILTGGLGPTEDDLTKQT
LAKFLGRELSFDPDAVEKLDRFFASRPDYARTPNNERQAQLVEGSTPLPNATGLAVGGLIEVDGVTYVVLPGPPSELKPM
VNNELVPLLSTGQKLYSRVLRFFGIGESQLVTILSEMIDQQSDPTIAPYAKTGEVTLRLSTKALSQAEADAKFEAVEKEI
LSHKTFEDQSLSEIFYGYGDDNSLAQVAFDLLKGQGKTISAAESLTAGLFQATLADFAGASAIFSGGFVTYSMEEKSRML
DIPLGELEGHGVVSAFTAGKMAEQARKLTESDLAVSLTGVAGPDSLEDHPAGTVFIGLASAAGTETIKVNIAGRSRRDVR
KIAVLHAFNLVRKTLLNS

Nucleotide


Download         Length: 1257 bp        

>NTDB_id=1137509 DQL23_RS10290 WP_060554240.1 2111714..2112970(-) (cinA) [Streptococcus gordonii strain NCTC7865]
ATGAAAGCAGAAATTATTGCTGTGGGCACCGAGATTCTGACAGGTCAGATTGTCAATACCAATGCCCAATTTTTATCTGA
GAAACTGGCTAGTCTGGGGATTGATGTCTATTTTCAGACAGCTGTAGGGGACAATGAAAATCGTCTCCTCTCTATCCTAG
AGATTGCAAAAGGACGTAGTAATCTAATTATCTTGACAGGAGGCTTGGGGCCAACAGAGGATGATTTGACCAAGCAGACC
TTGGCTAAGTTTTTAGGTCGAGAGTTGAGTTTTGACCCTGATGCTGTGGAAAAGTTGGATCGTTTTTTTGCCAGCCGACC
TGATTATGCTCGAACGCCCAACAATGAGCGTCAGGCTCAGCTGGTTGAAGGCTCAACTCCGTTACCAAATGCGACTGGTT
TAGCTGTTGGTGGTTTAATAGAAGTTGATGGGGTGACTTATGTAGTTCTGCCTGGTCCGCCTAGCGAGCTCAAACCTATG
GTCAATAACGAGTTGGTTCCCCTCTTATCCACAGGTCAAAAACTATACTCACGAGTGTTACGCTTCTTTGGTATCGGCGA
GAGTCAGCTAGTGACTATTTTGTCAGAGATGATTGATCAGCAAAGTGACCCTACCATTGCTCCTTATGCAAAGACGGGGG
AGGTTACGCTACGACTGTCCACCAAGGCCTTGAGTCAGGCAGAAGCTGACGCCAAGTTTGAGGCTGTGGAAAAGGAAATT
TTGTCACATAAGACTTTTGAAGACCAGTCTCTGTCAGAGATTTTCTATGGTTATGGGGATGACAATTCCTTGGCTCAGGT
GGCTTTTGACTTGCTAAAGGGTCAAGGAAAGACGATTTCAGCAGCAGAGAGTCTGACAGCAGGTCTCTTCCAAGCAACCT
TGGCAGATTTTGCTGGAGCTTCAGCTATTTTTTCAGGTGGCTTCGTCACCTATAGCATGGAGGAAAAGAGCCGGATGCTG
GACATTCCGCTGGGAGAGCTGGAGGGACATGGGGTTGTTTCAGCTTTTACGGCTGGGAAAATGGCAGAGCAGGCTAGAAA
GCTGACCGAAAGCGACTTGGCTGTCAGTCTGACAGGTGTGGCTGGACCAGATTCACTAGAAGATCATCCAGCTGGAACTG
TTTTTATTGGCTTGGCTAGTGCTGCAGGAACGGAAACTATTAAGGTCAATATTGCTGGACGTAGCCGGCGAGATGTACGA
AAAATCGCTGTTCTGCACGCCTTTAACCTAGTGCGAAAGACTTTATTAAATAGTTAA

Domains

Predicted by InterproScan.

Probable molybdopterin binding domain (MoCF_biosynth)

(5-169)

Damage-inducible protein CinA KH domain (CinA_KH)

(177-240)

Competence-damaged protein (CinA)

(262-415)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  cinA Streptococcus mitis SK321

77.698

99.761

0.775
  cinA Streptococcus mitis NCTC 12261

77.218

99.761

0.77
  cinA Streptococcus pneumoniae TIGR4

76.739

99.761

0.766
  cinA Streptococcus pneumoniae Rx1

76.739

99.761

0.766
  cinA Streptococcus pneumoniae R6

76.739

99.761

0.766
  cinA Streptococcus pneumoniae D39

76.499

99.761

0.763
  cinA Streptococcus mutans UA159

74.402

100

0.744
  cinA Streptococcus suis isolate S10

55.529

99.522

0.553
  cinA Bacillus subtilis subsp. subtilis str. 168

46.651

100

0.467

Multiple sequence alignment