Detailed information NTG1137367

Bioinformatically predicted

Overview

• Name: vicR
• Type: Regulator
• Locus tag: DQL34_RS06490
• Genome accession: NZ_LS483339
• Coordinates: 1206147..1206854 (-)
• Length: 235 a.a.
• NCBI ID: WP_011681206.1
• Uniprot ID: -
• Organism: Streptococcus thermophilus strain NCTC12958
• Function: repress comCDE expression; repress comX expression (predicted from homology) Competence regulation

Genomic Context

Location: 1201147..1211854

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DQL34_RS06465 (NCTC12958_01346)	yidA	1201490..1202299 (+)	810	WP_011226081.1	sugar-phosphatase	-
DQL34_RS06470 (NCTC12958_01347)	-	1202301..1203515 (+)	1215	WP_084830670.1	aminoacyltransferase	-
DQL34_RS06475 (NCTC12958_01348)	-	1203567..1203919 (-)	353	Protein_1214	YbaN family protein	-
DQL34_RS06480 (NCTC12958_01349)	vicX	1203996..1204805 (-)	810	WP_100262465.1	MBL fold metallo-hydrolase	Regulator
DQL34_RS06485 (NCTC12958_01350)	vicK	1204814..1206154 (-)	1341	WP_084828862.1	cell wall metabolism sensor histidine kinase VicK	Regulator
DQL34_RS06490 (NCTC12958_01351)	vicR	1206147..1206854 (-)	708	WP_011681206.1	response regulator YycF	Regulator
DQL34_RS06495 (NCTC12958_01352)	-	1207381..1208148 (+)	768	WP_011681207.1	amino acid ABC transporter ATP-binding protein	-
DQL34_RS06500 (NCTC12958_01353)	-	1208160..1208993 (+)	834	WP_002953142.1	transporter substrate-binding domain-containing protein	-
DQL34_RS06505 (NCTC12958_01354)	-	1209011..1209709 (+)	699	WP_014608374.1	amino acid ABC transporter permease	-
DQL34_RS06510 (NCTC12958_01355)	-	1209721..1210371 (+)	651	WP_100273221.1	amino acid ABC transporter permease	-
DQL34_RS06515 (NCTC12958_01356)	endA	1210442..1211323 (-)	882	WP_111679622.1	DNA/RNA non-specific endonuclease	Machinery gene
DQL34_RS06520 (NCTC12958_01357)	-	1211385..1211573 (-)	189	WP_011226090.1	DNA-directed RNA polymerase subunit beta	-

Sequence

Protein

• Length: 235 a.a.
• Molecular weight: 27058.98 Da
• Isoelectric Point: 5.0130

>NTDB_id=1137367 DQL34_RS06490 WP_011681206.1 1206147..1206854(-) (vicR) [Streptococcus thermophilus strain NCTC12958]
MKKILVVDDERPISDIIKFNLTKEGYEVVTAFDGREALEQFEAKKPDLVILDLMLPELDGLEVAKEIRKTSHTPIIMLSA
KDSEFDKVIGLEIGADDYVTKPFSNRELLARIKAHLRRTETIETAVEESSNSGKQEISIGELVIVPDAFVAKKRGNEVEL
THREFELLFHLATHMGQVMTREHLLETVWGYDYFGDVRTVDVTIRRLREKIEDTPSRPEYILTRRGVGYYMKNYD

Nucleotide

• Length: 708 bp

>NTDB_id=1137367 DQL34_RS06490 WP_011681206.1 1206147..1206854(-) (vicR) [Streptococcus thermophilus strain NCTC12958]
ATGAAAAAAATTCTAGTTGTTGATGATGAAAGACCAATCTCCGATATCATCAAGTTTAACCTTACTAAGGAGGGTTATGA
AGTGGTTACGGCCTTTGATGGGCGAGAAGCTTTGGAACAATTTGAAGCTAAAAAACCAGACTTGGTTATTCTGGACTTGA
TGTTGCCTGAACTGGATGGTTTGGAAGTTGCCAAGGAAATCCGTAAAACGAGCCACACACCGATTATCATGCTTTCAGCT
AAAGATAGTGAGTTTGATAAGGTTATCGGATTAGAAATTGGGGCAGACGACTATGTGACTAAGCCATTTTCTAACCGTGA
ATTGTTGGCACGTATTAAAGCCCACTTGCGTCGTACAGAAACGATTGAAACTGCAGTAGAAGAGAGCTCTAACTCTGGCA
AACAAGAAATTTCAATTGGTGAGTTGGTTATTGTTCCGGATGCCTTTGTTGCTAAAAAACGTGGAAACGAAGTTGAGTTG
ACCCACCGTGAATTTGAGTTACTCTTCCATTTGGCAACTCATATGGGACAAGTTATGACGCGTGAACATTTGCTTGAAAC
CGTTTGGGGCTATGACTATTTTGGGGATGTTCGTACTGTGGACGTAACGATTCGTCGTCTGCGTGAAAAAATTGAAGATA
CACCTAGCCGTCCTGAATATATCTTGACGCGTCGTGGTGTCGGTTATTACATGAAGAATTATGACTAG

Domains

Predicted by InterproScan.

• Response regulator receiver domain (Response_reg) (4-113)

• Transcriptional regulatory protein, C terminal (Trans_reg_C) (155-230)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vicR	Streptococcus mutans UA159	85.532	100	0.855
micA	Streptococcus pneumoniae Cp1015	80.258	99.149	0.796
covR	Lactococcus lactis subsp. lactis strain DGCC12653	46.32	98.298	0.455
covR	Streptococcus salivarius strain HSISS4	45.299	99.574	0.451
scnR	Streptococcus mutans UA159	38.559	100	0.387