Detailed information NTG1137368

Bioinformatically predicted

Overview

• Name: endA
• Type: Machinery gene
• Locus tag: DQL34_RS06515
• Genome accession: NZ_LS483339
• Coordinates: 1210442..1211323 (-)
• Length: 293 a.a.
• NCBI ID: WP_111679622.1
• Uniprot ID: -
• Organism: Streptococcus thermophilus strain NCTC12958
• Function: cleavage of dsDNA into ssDNA (predicted from homology) DNA processing

Genomic Context

Location: 1205442..1216323

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DQL34_RS06490 (NCTC12958_01351)	vicR	1206147..1206854 (-)	708	WP_011681206.1	response regulator YycF	Regulator
DQL34_RS06495 (NCTC12958_01352)	-	1207381..1208148 (+)	768	WP_011681207.1	amino acid ABC transporter ATP-binding protein	-
DQL34_RS06500 (NCTC12958_01353)	-	1208160..1208993 (+)	834	WP_002953142.1	transporter substrate-binding domain-containing protein	-
DQL34_RS06505 (NCTC12958_01354)	-	1209011..1209709 (+)	699	WP_014608374.1	amino acid ABC transporter permease	-
DQL34_RS06510 (NCTC12958_01355)	-	1209721..1210371 (+)	651	WP_100273221.1	amino acid ABC transporter permease	-
DQL34_RS06515 (NCTC12958_01356)	endA	1210442..1211323 (-)	882	WP_111679622.1	DNA/RNA non-specific endonuclease	Machinery gene
DQL34_RS06520 (NCTC12958_01357)	-	1211385..1211573 (-)	189	WP_011226090.1	DNA-directed RNA polymerase subunit beta	-
DQL34_RS06525 (NCTC12958_01358)	murA	1211575..1212846 (-)	1272	WP_024704149.1	UDP-N-acetylglucosamine 1-carboxyvinyltransferase	-
DQL34_RS06530 (NCTC12958_01359)	-	1212916..1213152 (-)	237	WP_002946959.1	DUF1146 family protein	-
DQL34_RS06535 (NCTC12958_01360)	galE	1213340..1214353 (-)	1014	WP_014621668.1	UDP-glucose 4-epimerase GalE	-
DQL34_RS12010 (NCTC12958_01361)	-	1214368..1215180 (-)	813	WP_223899678.1	hypothetical protein	-

Sequence

Protein

• Length: 293 a.a.
• Molecular weight: 31789.50 Da
• Isoelectric Point: 10.1789

>NTDB_id=1137368 DQL34_RS06515 WP_111679622.1 1210442..1211323(-) (endA) [Streptococcus thermophilus strain NCTC12958]
MAKRKTSLTNKQKRQLVTLIIAALIAVLGYLGTSNKLSPDNPIRQVASLVSGKSNKSIKSNGSTNSQSTPQEQLSETVMT
SSVKSQLGNSLEWNGAGAYIINRNKTNLNAKVSSQPYANNQVKTVQGQTVPTVANALLSKATRQYKNRQETGNGSTSWTP
AGWHQVQNLSGEYSHAVDRGHLLGYALIGGLKGFDASTSNPENIAVQTAWANQAYSDSSTGQNYYESLVRKALDKNKRVR
YRVTLIYEGENLIPSGTHLEAKSADGSLEFNVFVPNVQEGITLDYYSGKVTVN

Nucleotide

• Length: 882 bp

>NTDB_id=1137368 DQL34_RS06515 WP_111679622.1 1210442..1211323(-) (endA) [Streptococcus thermophilus strain NCTC12958]
ATGGCAAAAAGAAAGACATCTTTGACAAATAAACAGAAACGTCAGTTAGTCACATTAATAATAGCAGCTTTAATAGCTGT
TTTAGGTTACCTAGGAACCAGTAACAAGCTCTCGCCTGATAATCCTATCAGACAAGTAGCAAGTCTAGTTTCAGGGAAAT
CTAACAAATCCATTAAATCTAATGGTTCAACAAATAGTCAGTCTACACCACAAGAGCAGCTTTCTGAGACAGTAATGACT
AGTTCAGTCAAAAGCCAACTGGGTAATTCCTTGGAATGGAATGGAGCTGGGGCCTACATTATTAATAGAAATAAGACGAA
TCTAAATGCTAAGGTATCAAGCCAACCCTATGCTAATAACCAAGTCAAAACGGTTCAAGGACAAACTGTTCCTACAGTTG
CTAATGCCTTATTAAGTAAAGCAACTAGACAGTACAAAAATCGTCAAGAAACAGGGAATGGTTCAACCTCTTGGACACCA
GCTGGATGGCACCAGGTTCAAAATTTATCAGGAGAGTATAGCCATGCCGTAGATAGAGGCCATTTGCTAGGTTATGCACT
GATAGGTGGTTTGAAAGGATTTGACGCCTCGACTTCAAATCCAGAGAATATTGCTGTTCAAACTGCTTGGGCAAATCAAG
CATATAGCGATAGTTCTACAGGCCAAAACTATTATGAAAGCCTAGTACGAAAAGCTCTGGATAAAAACAAACGTGTTCGT
TATCGTGTGACCCTGATTTATGAAGGAGAGAATCTCATTCCATCAGGAACACATCTTGAAGCTAAGTCAGCAGACGGCTC
ACTTGAGTTTAATGTCTTTGTTCCAAATGTACAAGAGGGAATTACACTAGATTACTATTCAGGAAAAGTAACGGTGAATT
GA

Domains

Predicted by InterproScan.

• DNA/RNA non-specific endonuclease (Endonuclease_NS) (101-266)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
endA	Streptococcus pneumoniae Rx1	72.385	81.57	0.59
endA	Streptococcus pneumoniae D39	72.385	81.57	0.59
endA	Streptococcus pneumoniae R6	72.385	81.57	0.59
endA	Streptococcus pneumoniae TIGR4	72.385	81.57	0.59