Detailed information    

insolico Bioinformatically predicted

Overview

Name   cinA   Type   Machinery gene
Locus tag   DQL34_RS00430 Genome accession   NZ_LS483339
Coordinates   71260..72531 (+) Length   423 a.a.
NCBI ID   WP_111679087.1    Uniprot ID   -
Organism   Streptococcus thermophilus strain NCTC12958     
Function   facilitate localization of RecA (predicted from homology)   
Homologous recombination

Genomic Context

Location: 66260..77531
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DQL34_RS00400 (NCTC12958_00084) - 66593..67030 (-) 438 WP_111679081.1 LytTR family DNA-binding domain-containing protein -
  DQL34_RS00405 (NCTC12958_00085) - 67209..67514 (+) 306 WP_084830425.1 hypothetical protein -
  DQL34_RS00410 (NCTC12958_00086) mutL 67566..69509 (+) 1944 WP_011680601.1 DNA mismatch repair endonuclease MutL -
  DQL34_RS00415 (NCTC12958_00087) - 69640..69861 (+) 222 WP_011680602.1 hypothetical protein -
  DQL34_RS00420 (NCTC12958_00088) ruvA 70013..70603 (+) 591 WP_111679083.1 Holliday junction branch migration protein RuvA -
  DQL34_RS00425 (NCTC12958_00089) - 70610..71164 (+) 555 WP_111679085.1 DNA-3-methyladenine glycosylase I -
  DQL34_RS00430 (NCTC12958_00090) cinA 71260..72531 (+) 1272 WP_111679087.1 competence/damage-inducible protein A Machinery gene
  DQL34_RS00435 (NCTC12958_00091) recA 72567..73706 (+) 1140 WP_011680606.1 recombinase RecA Machinery gene
  DQL34_RS00440 (NCTC12958_00092) spx 73883..74281 (+) 399 WP_002949058.1 transcriptional regulator Spx -

Sequence

Protein


Download         Length: 423 a.a.        Molecular weight: 45913.36 Da        Isoelectric Point: 5.2053

>NTDB_id=1137334 DQL34_RS00430 WP_111679087.1 71260..72531(+) (cinA) [Streptococcus thermophilus strain NCTC12958]
MKAELIAVGTEILTGQITNTNAQFLSEKLAELGIDVYFHTAVGDNENRLLSVLDQSSKRSDLVILCGGLGPTEDDLTKQS
LAKFLGKELIFDEEASKKLDSFFATRPKHTRTPNNERQVQIVEGAVPLQNLTGLAVGGIITVEGVTYVVLPGPPSELKPM
VNRELIPALTENHTTLYSRVLRFFGVGESQLVTIIKDLIVNQTDPTIAPYAKVGEVTLRLSTKASSQEEADRKLDVLEEQ
IRSTKTLDGKSLSDLIYGYGESNSLAYEVFYLLKKYGKTITAAESLTAGLFQASVADFPGASQVFKGGFVTYSMEEKAKM
LGIPLSKLEEHGVVSHFTAEKMAEGARVKTGSDYGIALTGVAGPDALEGHQAGTVFIGIADRNQVRSIMVVIGGRSRSDV
RYISTLYAFNLVRQALLQEDNSI

Nucleotide


Download         Length: 1272 bp        

>NTDB_id=1137334 DQL34_RS00430 WP_111679087.1 71260..72531(+) (cinA) [Streptococcus thermophilus strain NCTC12958]
ATGAAAGCTGAATTGATTGCAGTAGGAACTGAAATTCTTACAGGGCAAATCACCAATACCAATGCCCAATTTTTATCTGA
AAAACTAGCTGAATTAGGAATTGACGTGTATTTTCACACAGCGGTAGGAGACAATGAAAACCGTCTACTTTCAGTCTTAG
ACCAGTCTAGTAAACGTAGCGATTTAGTTATACTCTGTGGAGGACTTGGCCCTACTGAGGATGACTTAACCAAACAATCA
TTGGCTAAGTTTTTAGGCAAAGAACTCATTTTTGATGAGGAGGCAAGTAAAAAACTGGATAGTTTCTTTGCTACTCGTCC
TAAACATACACGAACGCCTAATAATGAACGCCAAGTGCAAATTGTTGAGGGGGCTGTCCCCTTGCAAAATCTCACAGGTC
TGGCAGTTGGAGGAATTATTACTGTTGAAGGAGTGACCTATGTTGTCTTGCCTGGTCCGCCAAGTGAACTCAAACCTATG
GTGAACCGAGAGCTTATTCCAGCTCTTACAGAGAATCATACTACGCTTTATTCTAGAGTCCTAAGGTTTTTTGGTGTTGG
AGAAAGTCAATTGGTGACTATTATTAAAGATCTCATTGTTAACCAAACAGACCCAACCATTGCGCCCTATGCTAAAGTGG
GAGAAGTGACCCTTCGCTTATCAACAAAGGCATCGTCGCAAGAAGAAGCGGATCGAAAACTAGATGTTTTAGAAGAACAA
ATTCGTTCTACTAAAACTCTAGATGGAAAAAGCTTGTCTGATCTCATCTATGGATATGGAGAATCAAATAGCTTAGCTTA
TGAAGTGTTCTATTTGCTTAAGAAATATGGCAAAACTATTACTGCAGCTGAAAGTTTAACAGCTGGCTTATTTCAAGCTA
GTGTTGCTGATTTTCCTGGAGCTTCACAAGTATTCAAGGGTGGTTTTGTCACCTATAGCATGGAAGAAAAAGCTAAAATG
TTGGGTATTCCCTTATCTAAATTAGAAGAGCATGGTGTTGTTAGTCATTTTACAGCAGAAAAAATGGCTGAGGGTGCCCG
AGTTAAGACAGGTAGTGATTACGGAATTGCGCTTACTGGAGTAGCAGGACCAGATGCTTTGGAAGGGCATCAAGCAGGTA
CAGTCTTTATTGGTATTGCCGATAGAAACCAAGTGAGGTCAATTATGGTTGTTATAGGTGGAAGAAGTCGATCTGATGTT
AGATATATCAGTACACTCTATGCCTTTAACCTAGTTCGCCAAGCTTTATTACAAGAGGACAACTCAATTTAA

Domains

Predicted by InterproScan.

Damage-inducible protein CinA KH domain (CinA_KH)

(178-243)

Probable molybdopterin binding domain (MoCF_biosynth)

(5-170)

Competence-damaged protein (CinA)

(264-415)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  cinA Streptococcus mitis SK321

73.986

99.054

0.733
  cinA Streptococcus mitis NCTC 12261

72.792

99.054

0.721
  cinA Streptococcus pneumoniae TIGR4

71.599

99.054

0.709
  cinA Streptococcus pneumoniae D39

71.599

99.054

0.709
  cinA Streptococcus pneumoniae Rx1

71.36

99.054

0.707
  cinA Streptococcus pneumoniae R6

71.36

99.054

0.707
  cinA Streptococcus mutans UA159

69.596

99.527

0.693
  cinA Streptococcus suis isolate S10

54.087

98.345

0.532
  cinA Bacillus subtilis subsp. subtilis str. 168

44.418

99.527

0.442

Multiple sequence alignment