Detailed information    

insolico Bioinformatically predicted

Overview

Name   cinA   Type   Machinery gene
Locus tag   DQL35_RS10165 Genome accession   NZ_LS483325
Coordinates   2091860..2093131 (-) Length   423 a.a.
NCBI ID   WP_111678739.1    Uniprot ID   A0AAX2LFP0
Organism   Streptococcus equi subsp. zooepidemicus strain NCTC7022     
Function   require for competence (predicted from homology)   
Unclear

Genomic Context

Location: 2086860..2098131
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DQL35_RS10140 (NCTC7022_02048) - 2088750..2089049 (-) 300 WP_012516437.1 DUF1292 domain-containing protein -
  DQL35_RS10145 (NCTC7022_02049) ruvX 2089059..2089478 (-) 420 WP_111678736.1 Holliday junction resolvase RuvX -
  DQL35_RS10150 (NCTC7022_02050) - 2089475..2089744 (-) 270 WP_012516439.1 IreB family regulatory phosphoprotein -
  DQL35_RS10155 (NCTC7022_02051) spx 2089857..2090255 (-) 399 WP_012516440.1 transcriptional regulator Spx -
  DQL35_RS10160 (NCTC7022_02052) recA 2090630..2091766 (-) 1137 WP_042671444.1 recombinase RecA Machinery gene
  DQL35_RS10165 (NCTC7022_02053) cinA 2091860..2093131 (-) 1272 WP_111678739.1 competence/damage-inducible protein A Machinery gene
  DQL35_RS10170 (NCTC7022_02054) - 2093817..2094107 (-) 291 WP_012516443.1 hypothetical protein -
  DQL35_RS10175 (NCTC7022_02055) - 2094101..2094673 (-) 573 WP_111678741.1 phospholipase -
  DQL35_RS10180 (NCTC7022_02056) - 2094970..2095815 (+) 846 WP_012516446.1 helix-turn-helix domain-containing protein -
  DQL35_RS10185 (NCTC7022_02057) - 2096259..2096810 (-) 552 WP_111678743.1 DNA-3-methyladenine glycosylase I -
  DQL35_RS10190 (NCTC7022_02058) ruvA 2096820..2097416 (-) 597 WP_037580030.1 Holliday junction branch migration protein RuvA -

Sequence

Protein


Download         Length: 423 a.a.        Molecular weight: 45752.45 Da        Isoelectric Point: 5.8304

>NTDB_id=1136601 DQL35_RS10165 WP_111678739.1 2091860..2093131(-) (cinA) [Streptococcus equi subsp. zooepidemicus strain NCTC7022]
MKAELIAVGTEILTGQIVNTNAQFLSEKMAELGIDVYFQTAVGDNEERLLSVIDIASQRSDLVILCGGLGPTDDDLTKQT
LAKYLGKALVFDEQAGQKLDAFFAHRKQAVRTPNNQRQAQLIEGSIALQNQTGLAVGGLIAVDRVTYVVLPGPPSELKPM
VKNELVPLLSASHASLYSRVLRFFGIGESQLVTALEDLIKHQTDPTIAPYAKTGEVTLRLSTKSDNQALADERLDRLEAQ
LLSIKTVDNQPLRRLLYGYGEDNSLARETFELLKRSGKTITAAESLTAGLFQAQLTDFAGASQVFNGGFITYSIEEKARM
LGIPLGELQRHGVVSSFTAEQMAAQARCLTNSDIGIGLTGVAGPEALEGQPAGTVFIGLATKNKVESLKVVIGGRSRLDV
RYIAALYAFNMVRKTLLKSENLL

Nucleotide


Download         Length: 1272 bp        

>NTDB_id=1136601 DQL35_RS10165 WP_111678739.1 2091860..2093131(-) (cinA) [Streptococcus equi subsp. zooepidemicus strain NCTC7022]
ATGAAAGCTGAACTCATTGCGGTGGGAACCGAGATTCTGACTGGTCAGATTGTAAATACCAATGCTCAATTTTTATCAGA
AAAAATGGCAGAGCTTGGTATTGATGTTTATTTTCAAACAGCTGTAGGAGATAATGAAGAGCGTTTGCTTTCTGTTATTG
ATATTGCTAGCCAGCGAAGTGATTTAGTGATTTTATGTGGTGGTCTTGGTCCAACAGATGATGATCTAACGAAGCAGACC
TTAGCTAAGTATCTAGGAAAAGCTTTGGTCTTTGATGAGCAGGCAGGTCAAAAATTAGATGCTTTTTTTGCACATCGTAA
GCAGGCTGTTAGGACACCAAATAACCAACGTCAGGCGCAGCTGATTGAAGGCTCTATTGCTTTGCAAAATCAAACAGGAC
TTGCAGTAGGTGGGTTAATAGCTGTAGATAGGGTAACCTATGTTGTCTTACCAGGGCCTCCAAGTGAGCTAAAGCCTATG
GTAAAAAATGAGCTGGTGCCCCTTCTTTCAGCTAGTCATGCCAGTCTATATTCAAGAGTGCTGCGTTTTTTTGGCATTGG
TGAAAGTCAACTGGTGACTGCTCTGGAGGATTTGATTAAGCATCAAACAGATCCTACCATTGCTCCTTATGCAAAGACCG
GCGAGGTAACACTGCGACTATCCACAAAGTCTGACAACCAAGCATTAGCTGATGAAAGGCTGGATCGACTAGAGGCGCAG
CTCTTATCCATAAAAACTGTAGATAATCAACCCTTACGGCGTTTGCTTTATGGCTATGGGGAGGATAATTCCTTGGCGCG
TGAGACCTTTGAGCTATTGAAGCGAAGTGGTAAGACGATAACAGCAGCTGAAAGCTTAACAGCAGGACTGTTTCAAGCTC
AGTTAACTGATTTTGCGGGAGCTTCACAGGTGTTTAACGGTGGCTTTATCACCTACAGCATTGAAGAAAAAGCAAGAATG
CTTGGCATTCCATTGGGTGAGCTACAAAGGCATGGTGTTGTGAGCTCTTTTACAGCTGAGCAAATGGCTGCACAGGCACG
CTGCTTGACCAATTCAGATATCGGTATTGGTCTAACAGGTGTTGCTGGTCCAGAGGCACTCGAGGGACAGCCAGCAGGAA
CAGTTTTCATTGGCCTTGCCACTAAGAATAAGGTAGAATCTCTTAAAGTTGTTATAGGAGGCCGTAGCCGTTTGGACGTG
CGGTATATTGCTGCCCTATATGCTTTTAATATGGTTCGTAAAACTTTATTAAAATCAGAGAATTTGCTATAA

Domains

Predicted by InterproScan.

Damage-inducible protein CinA KH domain (CinA_KH)

(178-241)

Probable molybdopterin binding domain (MoCF_biosynth)

(5-169)

Competence-damaged protein (CinA)

(263-416)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  cinA Streptococcus mutans UA159

70.686

100

0.707
  cinA Streptococcus mitis NCTC 12261

70.264

98.582

0.693
  cinA Streptococcus mitis SK321

70.024

98.582

0.69
  cinA Streptococcus pneumoniae TIGR4

69.784

98.582

0.688
  cinA Streptococcus pneumoniae Rx1

69.784

98.582

0.688
  cinA Streptococcus pneumoniae R6

69.784

98.582

0.688
  cinA Streptococcus pneumoniae D39

69.544

98.582

0.686
  cinA Streptococcus suis isolate S10

53.938

99.054

0.534
  cinA Bacillus subtilis subsp. subtilis str. 168

47.847

98.818

0.473

Multiple sequence alignment