Detailed information    

insolico Bioinformatically predicted

Overview

Name   comYC   Type   Machinery gene
Locus tag   DQL09_RS00675 Genome accession   NZ_LS483307
Coordinates   104949..105275 (+) Length   108 a.a.
NCBI ID   WP_111676998.1    Uniprot ID   -
Organism   Streptococcus pyogenes strain NCTC5163     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 99949..110275
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DQL09_RS00660 (NCTC5163_00133) - 102581..102946 (+) 366 WP_111676997.1 DUF1033 family protein -
  DQL09_RS00665 (NCTC5163_00134) comYA 103039..103977 (+) 939 WP_063812149.1 competence type IV pilus ATPase ComGA Machinery gene
  DQL09_RS00670 (NCTC5163_00135) comYB 103913..104947 (+) 1035 WP_011054115.1 competence type IV pilus assembly protein ComGB Machinery gene
  DQL09_RS00675 (NCTC5163_00136) comYC 104949..105275 (+) 327 WP_111676998.1 competence type IV pilus major pilin ComGC Machinery gene
  DQL09_RS00680 (NCTC5163_00137) comGD 105250..105678 (+) 429 WP_002986548.1 competence type IV pilus minor pilin ComGD -
  DQL09_RS00685 (NCTC5163_00138) comGE 105635..105919 (+) 285 WP_002987779.1 competence type IV pilus minor pilin ComGE -
  DQL09_RS00690 (NCTC5163_00139) comYF 105912..106346 (+) 435 WP_002986542.1 competence type IV pilus minor pilin ComGF Machinery gene
  DQL09_RS00695 (NCTC5163_00140) comGG 106330..106656 (+) 327 WP_002986539.1 competence type IV pilus minor pilin ComGG -
  DQL09_RS00700 (NCTC5163_00141) comYH 106754..107707 (+) 954 WP_111676999.1 class I SAM-dependent methyltransferase Machinery gene
  DQL09_RS00705 (NCTC5163_00142) - 107766..108962 (+) 1197 WP_020904834.1 acetate kinase -
  DQL09_RS00710 - 109149..109457 (+) 309 WP_111677000.1 hypothetical protein -

Sequence

Protein


Download         Length: 108 a.a.        Molecular weight: 12360.32 Da        Isoelectric Point: 10.0992

>NTDB_id=1135752 DQL09_RS00675 WP_111676998.1 104949..105275(+) (comYC) [Streptococcus pyogenes strain NCTC5163]
MINQWNNLRHKNLKGFTLLEMLLVILVISVLMLLFVPNLSKQKDRVTETGNAAVVKLVENQAELYELSQGSKPSLSQLKA
DGSITEKQEKAYQNYYNKHKNEKARLSN

Nucleotide


Download         Length: 327 bp        

>NTDB_id=1135752 DQL09_RS00675 WP_111676998.1 104949..105275(+) (comYC) [Streptococcus pyogenes strain NCTC5163]
ATGATTAATCAATGGAACAACTTACGACACAAGAATCTAAAAGGATTTACTCTTCTAGAAATGTTATTGGTGATTCTTGT
TATCAGTGTTTTGATGCTATTATTTGTGCCTAATTTAAGCAAGCAAAAAGACAGGGTTACAGAAACAGGTAATGCCGCTG
TTGTTAAATTAGTGGAGAATCAAGCAGAACTATATGAATTATCTCAAGGCTCAAAACCAAGTTTGAGCCAGTTAAAGGCA
GATGGTAGTATCACTGAGAAACAAGAAAAAGCTTATCAAAACTATTATAACAAACATAAAAATGAAAAAGCCCGTCTTAG
CAATTAA

Domains

Predicted by InterproScan.

Prokaryotic N-terminal methylation motif (N_methyl)

(12-34)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comYC Streptococcus gordonii str. Challis substr. CH1

56.19

97.222

0.546
  comGC/cglC Streptococcus mitis SK321

60.87

85.185

0.519
  comGC Lactococcus lactis subsp. cremoris KW2

53.922

94.444

0.509
  comGC/cglC Streptococcus mitis NCTC 12261

59.783

85.185

0.509
  comGC/cglC Streptococcus pneumoniae R6

58.696

85.185

0.5
  comGC/cglC Streptococcus pneumoniae Rx1

58.696

85.185

0.5
  comGC/cglC Streptococcus pneumoniae D39

58.696

85.185

0.5
  comGC/cglC Streptococcus pneumoniae TIGR4

58.696

85.185

0.5
  comYC Streptococcus mutans UA140

51.485

93.519

0.481
  comYC Streptococcus mutans UA159

51.485

93.519

0.481
  comYC Streptococcus suis isolate S10

58.025

75

0.435

Multiple sequence alignment