Detailed information    

insolico Bioinformatically predicted

Overview

Name   cinA   Type   Machinery gene
Locus tag   H1W86_RS00360 Genome accession   NZ_LR822042
Coordinates   62838..64109 (+) Length   423 a.a.
NCBI ID   WP_100262628.1    Uniprot ID   -
Organism   Streptococcus thermophilus isolate STH_CIRM_1358     
Function   facilitate localization of RecA (predicted from homology)   
Homologous recombination

Genomic Context

Location: 57838..69109
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  H1W86_RS00330 (STHERMO_0058) - 58173..58564 (-) 392 Protein_45 LytTR family DNA-binding domain-containing protein -
  H1W86_RS00335 (STHERMO_0059) - 58788..59093 (+) 306 WP_002949050.1 hypothetical protein -
  H1W86_RS00340 (STHERMO_0060) mutL 59145..61088 (+) 1944 WP_014607839.1 DNA mismatch repair endonuclease MutL -
  H1W86_RS00345 (STHERMO_0061) - 61218..61439 (+) 222 WP_002949052.1 hypothetical protein -
  H1W86_RS00350 (STHERMO_0062) ruvA 61591..62181 (+) 591 WP_011680603.1 Holliday junction branch migration protein RuvA -
  H1W86_RS00355 (STHERMO_0063) - 62188..62742 (+) 555 WP_111679085.1 DNA-3-methyladenine glycosylase I -
  H1W86_RS00360 (STHERMO_0064) cinA 62838..64109 (+) 1272 WP_100262628.1 competence/damage-inducible protein A Machinery gene
  H1W86_RS00365 (STHERMO_0065) recA 64145..65284 (+) 1140 WP_180479557.1 recombinase RecA Machinery gene
  H1W86_RS00370 (STHERMO_0066) spx 65461..65859 (+) 399 WP_180479560.1 transcriptional regulator Spx -

Sequence

Protein


Download         Length: 423 a.a.        Molecular weight: 45912.27 Da        Isoelectric Point: 5.0948

>NTDB_id=1132093 H1W86_RS00360 WP_100262628.1 62838..64109(+) (cinA) [Streptococcus thermophilus isolate STH_CIRM_1358]
MKAELIAVGTEILTGQITNTNAQFLSEKLAELGIDVYFHTAVGDNENRLLSVLDQSSKRSDLVILCGGLGPTEDDLTKQS
LAKFLGKELIFDEEASKKLDSFFATRPKHTRTPNNERQAQIVEGAVPLQNLTGLAVGGIITVEGVTYVVLPGPPSELKPM
VNQELIPALTENHTTLYSRVLRFFGVGESQLVTIIKDLIVNQTDPTIAPYAKVGEVTLRLSTKASSQEEADRKLDVLEEQ
IRSTKTLDGKSLSDLIYGYGESNSLAYEVFYLLKKYGKTITAAESLTAGLFQASVADFPGASQVFKGGFVTYSMEEKAKM
LGIPLSKLEEHGVVSHFTAEKMAEGARVKTDSDYGIALTGVAGPDALEGHQAGTVFIGIADRNQVRSIKVVIGGRSRSDV
RYISTLYAFNLVRQALLQEDNSI

Nucleotide


Download         Length: 1272 bp        

>NTDB_id=1132093 H1W86_RS00360 WP_100262628.1 62838..64109(+) (cinA) [Streptococcus thermophilus isolate STH_CIRM_1358]
ATGAAAGCTGAATTGATTGCAGTAGGAACTGAAATTCTTACAGGGCAAATCACCAATACCAATGCCCAATTTTTATCTGA
AAAACTAGCTGAATTAGGAATTGACGTGTATTTTCACACAGCGGTAGGAGACAATGAAAACCGTCTACTTTCAGTCTTAG
ACCAGTCTAGTAAACGTAGCGATTTAGTTATACTCTGTGGAGGACTTGGGCCTACTGAGGATGACTTAACCAAACAATCA
TTGGCTAAGTTTTTAGGCAAAGAACTCATTTTTGATGAGGAGGCAAGTAAAAAACTGGATAGTTTCTTTGCTACTCGTCC
TAAACATACACGAACGCCTAATAATGAACGCCAAGCGCAAATTGTTGAGGGGGCTGTCCCCTTGCAAAATCTCACAGGTC
TGGCAGTTGGAGGAATTATTACTGTTGAAGGAGTGACCTATGTTGTCTTGCCTGGTCCGCCAAGTGAACTCAAACCTATG
GTGAACCAAGAGCTTATTCCAGCTCTTACAGAGAATCATACTACGCTTTATTCTAGAGTCCTAAGGTTTTTTGGTGTTGG
AGAAAGTCAATTGGTGACTATTATTAAAGATCTCATTGTTAACCAAACAGACCCAACCATTGCGCCCTATGCTAAAGTGG
GAGAAGTGACCCTTCGCTTATCAACAAAGGCATCGTCGCAAGAAGAAGCGGATCGAAAACTAGATGTTTTAGAAGAACAA
ATTCGTTCTACTAAAACTCTAGATGGAAAAAGCTTGTCTGATCTCATCTATGGATATGGAGAATCAAATAGCTTAGCTTA
TGAAGTGTTCTATTTGCTTAAAAAATATGGCAAAACTATTACTGCAGCTGAAAGTTTAACAGCTGGCTTATTTCAAGCTA
GTGTTGCTGATTTTCCTGGAGCTTCACAAGTATTCAAGGGTGGTTTTGTCACCTATAGCATGGAAGAAAAAGCTAAAATG
TTGGGTATTCCCTTATCTAAATTAGAAGAGCATGGTGTTGTTAGTCATTTTACAGCAGAAAAAATGGCTGAGGGTGCCCG
AGTTAAGACAGATAGTGATTACGGAATTGCGCTTACTGGAGTAGCAGGACCAGATGCTTTGGAAGGGCATCAAGCAGGTA
CAGTCTTTATTGGTATTGCCGATAGAAACCAAGTGCGGTCAATTAAGGTTGTTATAGGTGGAAGAAGTCGATCTGATGTT
AGATATATCAGTACACTCTATGCCTTTAACCTAGTTCGCCAAGCTTTATTACAAGAGGACAACTCAATTTAA

Domains

Predicted by InterproScan.

Competence-damaged protein (CinA)

(264-415)

Probable molybdopterin binding domain (MoCF_biosynth)

(5-170)

Damage-inducible protein CinA KH domain (CinA_KH)

(178-243)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  cinA Streptococcus mitis SK321

74.463

99.054

0.738
  cinA Streptococcus mitis NCTC 12261

73.27

99.054

0.726
  cinA Streptococcus pneumoniae TIGR4

72.076

99.054

0.714
  cinA Streptococcus pneumoniae Rx1

71.838

99.054

0.712
  cinA Streptococcus pneumoniae R6

71.838

99.054

0.712
  cinA Streptococcus pneumoniae D39

71.599

99.054

0.709
  cinA Streptococcus mutans UA159

70.071

99.527

0.697
  cinA Streptococcus suis isolate S10

54.327

98.345

0.534
  cinA Bacillus subtilis subsp. subtilis str. 168

44.418

99.527

0.442

Multiple sequence alignment