Detailed information    

insolico Bioinformatically predicted

Overview

Name   comYB   Type   Machinery gene
Locus tag   H1W80_RS08455 Genome accession   NZ_LR822040
Coordinates   1633229..1634329 (-) Length   366 a.a.
NCBI ID   WP_180473354.1    Uniprot ID   -
Organism   Streptococcus thermophilus isolate STH_CIRM_1125     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1628229..1639329
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  H1W80_RS09725 (STHERMO_1899) - 1628554..1628829 (-) 276 WP_232086519.1 CAAX protease -
  H1W80_RS08415 (STHERMO_1900) - 1628841..1629038 (-) 198 WP_002885716.1 helix-turn-helix transcriptional regulator -
  H1W80_RS08420 (STHERMO_1901) - 1629287..1630480 (-) 1194 WP_180473352.1 acetate kinase -
  H1W80_RS08425 (STHERMO_1902) comYH 1630536..1631492 (-) 957 WP_011226622.1 class I SAM-dependent methyltransferase Machinery gene
  H1W80_RS08430 (STHERMO_1903) comGG 1631537..1631854 (-) 318 WP_002952035.1 competence type IV pilus minor pilin ComGG -
  H1W80_RS08435 (STHERMO_1904) comYF 1631832..1632269 (-) 438 WP_082309153.1 competence type IV pilus minor pilin ComGF Machinery gene
  H1W80_RS08440 (STHERMO_1905) comGE 1632253..1632546 (-) 294 WP_180473353.1 competence type IV pilus minor pilin ComGE -
  H1W80_RS08445 (STHERMO_1906) comYD 1632518..1632946 (-) 429 WP_011226626.1 competence type IV pilus minor pilin ComGD Machinery gene
  H1W80_RS08450 (STHERMO_1907) comYC 1632906..1633232 (-) 327 WP_002946126.1 competence type IV pilus major pilin ComGC Machinery gene
  H1W80_RS08455 (STHERMO_1908) comYB 1633229..1634329 (-) 1101 WP_180473354.1 competence type IV pilus assembly protein ComGB Machinery gene
  H1W80_RS08460 (STHERMO_1909) comGA/cglA/cilD 1634211..1635152 (-) 942 WP_022096896.1 competence type IV pilus ATPase ComGA Machinery gene
  H1W80_RS08465 (STHERMO_1910) - 1635233..1635595 (-) 363 WP_014608746.1 DUF1033 family protein -

Sequence

Protein


Download         Length: 366 a.a.        Molecular weight: 41771.88 Da        Isoelectric Point: 10.1405

>NTDB_id=1132026 H1W80_RS08455 WP_180473354.1 1633229..1634329(-) (comYB) [Streptococcus thermophilus isolate STH_CIRM_1125]
MPEKISKTIRRPTGISSWKVWLNKDVSLRGISKGKKLKISQQVKVIQLFKQLLKAGFTLTEIVAFLERSHLLKEASLSLM
KESLIRGDRLDQMLALVGFSDNIVTQISLADKHGNLLGSLTKIETHMLRMTKVRKKLMEVATYPILLLGFLILIMLGLKN
YLLPQLLEGDGKNNWAVQLVQIFPQLFFVSLCGLLVLGLILYLWVKRQSALVFYRRMAKIPFIGQTVRLYTTAYYAREWG
NLLGQGVDLLDLVALMQEQKSKLFRELGADLEEALMLGQSFPERIASHPFFTKELSLIIAYGEANARLGYELEVYAEEVW
QNFFNRLNKATTFVQPLIFVIVAVVIVMIYVAMLLPMYQNMEGMMS

Nucleotide


Download         Length: 1101 bp        

>NTDB_id=1132026 H1W80_RS08455 WP_180473354.1 1633229..1634329(-) (comYB) [Streptococcus thermophilus isolate STH_CIRM_1125]
TTGCCAGAGAAAATTTCCAAAACCATTCGTCGACCAACTGGAATCAGCAGTTGGAAGGTTTGGTTAAACAAGGATGTCTC
ACTGAGAGGGATATCCAAGGGGAAAAAATTAAAGATTAGTCAGCAAGTTAAGGTTATCCAGCTCTTCAAACAACTTTTAA
AGGCCGGTTTTACCTTAACTGAAATCGTAGCCTTTTTGGAGCGAAGTCACTTGCTGAAAGAAGCATCCTTGTCTCTTATG
AAAGAGAGTTTAATACGCGGTGATAGGTTGGATCAGATGTTAGCGTTAGTGGGGTTTTCGGACAATATTGTTACTCAGAT
TTCTCTTGCTGACAAGCACGGTAATCTTCTAGGGAGTCTAACAAAGATTGAAACCCATATGCTTCGTATGACAAAGGTTC
GCAAGAAACTCATGGAGGTGGCGACTTATCCCATACTACTTCTGGGTTTTCTGATTCTGATTATGCTAGGACTTAAAAAT
TATCTTCTACCCCAACTCTTAGAGGGTGATGGTAAGAATAATTGGGCTGTACAGTTGGTTCAAATTTTTCCCCAGCTTTT
TTTTGTGAGTTTGTGTGGACTCCTTGTGTTGGGTTTAATTCTCTATCTATGGGTGAAACGACAGTCAGCCCTTGTTTTTT
ATAGGCGAATGGCCAAAATCCCTTTTATTGGTCAGACAGTAAGGCTTTACACGACCGCCTATTATGCTAGGGAATGGGGA
AATTTATTAGGTCAAGGCGTTGATTTGCTAGATTTGGTGGCTCTTATGCAAGAGCAAAAGTCTAAACTCTTCCGTGAGCT
GGGAGCCGATTTGGAAGAAGCCCTGATGCTGGGACAGAGTTTTCCTGAACGTATTGCCAGTCATCCGTTTTTTACTAAGG
AGCTCTCACTAATTATTGCTTATGGGGAGGCCAATGCGAGGTTGGGCTATGAGTTGGAAGTTTATGCCGAGGAGGTTTGG
CAAAACTTCTTTAACCGTCTTAATAAGGCAACAACCTTTGTGCAACCCCTCATTTTTGTTATTGTTGCAGTTGTGATTGT
AATGATCTATGTAGCCATGCTATTACCAATGTATCAAAATATGGAAGGAATGATGTCATGA

Domains

Predicted by InterproScan.

Type II secretion system (T2SS), protein F (T2SSF)

(51-164)

Type II secretion system (T2SS), protein F (T2SSF)

(236-356)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comYB Streptococcus mutans UA140

54.386

93.443

0.508
  comYB Streptococcus mutans UA159

54.386

93.443

0.508
  comYB Streptococcus gordonii str. Challis substr. CH1

50.877

93.443

0.475
  comGB/cglB Streptococcus mitis NCTC 12261

50.151

90.437

0.454
  comGB/cglB Streptococcus mitis SK321

49.394

90.164

0.445
  comGB/cglB Streptococcus pneumoniae Rx1

49.39

89.617

0.443
  comGB/cglB Streptococcus pneumoniae D39

49.39

89.617

0.443
  comGB/cglB Streptococcus pneumoniae R6

49.39

89.617

0.443
  comGB/cglB Streptococcus pneumoniae TIGR4

49.39

89.617

0.443
  comGB Lactococcus lactis subsp. cremoris KW2

46.061

90.164

0.415

Multiple sequence alignment