Detailed information NTG1132023

Bioinformatically predicted

Overview

• Name: comYF
• Type: Machinery gene
• Locus tag: H1W80_RS08435
• Genome accession: NZ_LR822040
• Coordinates: 1631832..1632269 (-)
• Length: 145 a.a.
• NCBI ID: WP_082309153.1
• Uniprot ID: -
• Organism: Streptococcus thermophilus isolate STH_CIRM_1125
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1626832..1637269

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
H1W80_RS08400 (STHERMO_1896)	-	1626896..1627558 (-)	663	WP_023909970.1	CPBP family intramembrane glutamic endopeptidase	-
H1W80_RS08405 (STHERMO_1897)	-	1627655..1628098 (-)	444	WP_180473351.1	CAAX protease	-
H1W80_RS09720 (STHERMO_1898)	-	1628172..1628597 (-)	426	WP_232086518.1	CPBP family intramembrane glutamic endopeptidase	-
H1W80_RS09725 (STHERMO_1899)	-	1628554..1628829 (-)	276	WP_232086519.1	CAAX protease	-
H1W80_RS08415 (STHERMO_1900)	-	1628841..1629038 (-)	198	WP_002885716.1	helix-turn-helix transcriptional regulator	-
H1W80_RS08420 (STHERMO_1901)	-	1629287..1630480 (-)	1194	WP_180473352.1	acetate kinase	-
H1W80_RS08425 (STHERMO_1902)	comYH	1630536..1631492 (-)	957	WP_011226622.1	class I SAM-dependent methyltransferase	Machinery gene
H1W80_RS08430 (STHERMO_1903)	comGG	1631537..1631854 (-)	318	WP_002952035.1	competence type IV pilus minor pilin ComGG	-
H1W80_RS08435 (STHERMO_1904)	comYF	1631832..1632269 (-)	438	WP_082309153.1	competence type IV pilus minor pilin ComGF	Machinery gene
H1W80_RS08440 (STHERMO_1905)	comGE	1632253..1632546 (-)	294	WP_180473353.1	competence type IV pilus minor pilin ComGE	-
H1W80_RS08445 (STHERMO_1906)	comYD	1632518..1632946 (-)	429	WP_011226626.1	competence type IV pilus minor pilin ComGD	Machinery gene
H1W80_RS08450 (STHERMO_1907)	comYC	1632906..1633232 (-)	327	WP_002946126.1	competence type IV pilus major pilin ComGC	Machinery gene
H1W80_RS08455 (STHERMO_1908)	comYB	1633229..1634329 (-)	1101	WP_180473354.1	competence type IV pilus assembly protein ComGB	Machinery gene
H1W80_RS08460 (STHERMO_1909)	comGA/cglA/cilD	1634211..1635152 (-)	942	WP_022096896.1	competence type IV pilus ATPase ComGA	Machinery gene
H1W80_RS08465 (STHERMO_1910)	-	1635233..1635595 (-)	363	WP_014608746.1	DUF1033 family protein	-

Sequence

Protein

• Length: 145 a.a.
• Molecular weight: 16423.93 Da
• Isoelectric Point: 8.9531

>NTDB_id=1132023 H1W80_RS08435 WP_082309153.1 1631832..1632269(-) (comYF) [Streptococcus thermophilus isolate STH_CIRM_1125]
MYLSSKLRAFTLLECLVALLVIAGSVQVYQGLTTVLVSNVKQVRQQENQDWLLFVQQMEAELEGCQLVKVEGNKLYVKQD
NQYLAFGLSSASDFRKTNADGRGYQPMLFDVKSSKVSQKNQIVTIQVTLKNELQRSFVYAFEKTG

Nucleotide

• Length: 438 bp

>NTDB_id=1132023 H1W80_RS08435 WP_082309153.1 1631832..1632269(-) (comYF) [Streptococcus thermophilus isolate STH_CIRM_1125]
ATGTATCTAAGCAGTAAGCTGCGTGCCTTTACCCTCTTGGAATGTCTAGTGGCCTTGTTGGTCATTGCTGGCTCAGTTCA
AGTTTATCAAGGGTTAACCACTGTACTTGTTAGTAATGTTAAGCAGGTAAGACAACAAGAAAACCAAGATTGGCTTCTAT
TTGTTCAACAAATGGAGGCAGAATTAGAAGGATGTCAGTTGGTCAAGGTAGAGGGGAACAAACTCTATGTCAAGCAGGAT
AATCAATACTTGGCTTTTGGTCTTTCAAGTGCCTCTGATTTTCGAAAAACAAATGCTGATGGTCGAGGTTATCAACCAAT
GCTTTTCGATGTCAAATCTAGTAAGGTAAGTCAAAAGAACCAGATAGTTACCATCCAAGTGACTCTTAAAAATGAACTAC
AAAGGAGTTTTGTTTATGCTTTTGAAAAAACAGGTTAG

Domains

Predicted by InterproScan.

• Putative Competence protein ComGF (ComGF) (39-134)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comYF	Streptococcus mutans UA140	58.156	97.241	0.566
comYF	Streptococcus mutans UA159	57.447	97.241	0.559
comGF/cglF	Streptococcus pneumoniae D39	48.571	96.552	0.469
comGF/cglF	Streptococcus pneumoniae Rx1	48.571	96.552	0.469
comGF/cglF	Streptococcus pneumoniae R6	48.571	96.552	0.469
comGF/cglF	Streptococcus pneumoniae TIGR4	48.571	96.552	0.469
comGF/cglF	Streptococcus mitis NCTC 12261	47.518	97.241	0.462
comGF/cglF	Streptococcus mitis SK321	46.099	97.241	0.448
comGF	Lactococcus lactis subsp. cremoris KW2	45.324	95.862	0.434