Detailed information    

insolico Bioinformatically predicted

Overview

Name   cinA   Type   Machinery gene
Locus tag   H1W80_RS00355 Genome accession   NZ_LR822040
Coordinates   61915..63186 (+) Length   423 a.a.
NCBI ID   WP_087009608.1    Uniprot ID   -
Organism   Streptococcus thermophilus isolate STH_CIRM_1125     
Function   facilitate localization of RecA (predicted from homology)   
Homologous recombination

Genomic Context

Location: 56915..68186
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  H1W80_RS00325 (STHERMO_0063) - 57253..57641 (-) 389 Protein_43 LytTR family DNA-binding domain-containing protein -
  H1W80_RS00330 (STHERMO_0064) - 57865..58170 (+) 306 WP_087009606.1 hypothetical protein -
  H1W80_RS00335 (STHERMO_0065) mutL 58222..60165 (+) 1944 WP_011680601.1 DNA mismatch repair endonuclease MutL -
  H1W80_RS00340 (STHERMO_0066) - 60295..60516 (+) 222 WP_011680602.1 hypothetical protein -
  H1W80_RS00345 (STHERMO_0067) ruvA 60668..61258 (+) 591 WP_011680603.1 Holliday junction branch migration protein RuvA -
  H1W80_RS00350 - 61265..61819 (+) 555 Protein_48 DNA-3-methyladenine glycosylase I -
  H1W80_RS00355 (STHERMO_0070) cinA 61915..63186 (+) 1272 WP_087009608.1 competence/damage-inducible protein A Machinery gene
  H1W80_RS00360 (STHERMO_0071) recA 63222..64376 (+) 1155 WP_087009609.1 recombinase RecA Machinery gene
  H1W80_RS00365 (STHERMO_0072) spx 64554..64952 (+) 399 WP_002949058.1 transcriptional regulator Spx -

Sequence

Protein


Download         Length: 423 a.a.        Molecular weight: 45872.25 Da        Isoelectric Point: 5.3398

>NTDB_id=1131973 H1W80_RS00355 WP_087009608.1 61915..63186(+) (cinA) [Streptococcus thermophilus isolate STH_CIRM_1125]
MKAELITVGTEILTGQITNTNAQFLSEKLAELGIDVYFHTAVGDNENRLLSVLDQSSKRSDLVILCGGLGPTEDDLTKQT
LAKFLGKELIFDEEASKKLDSFFATRPKHTRTPNNERQAQIVEGAVPLQNLTGLAVGGIITVEGVTYVVLPGPPSELKPM
VNQELIPALTENHTTLHSRVLRFFGVGESQLVTIIKDLIVNQTDPTIAPYAKVGEVTLRLSTKASSQEEADRKLDVLEEQ
IRSTKTLDGKSLSDLIYGYGESNSLAYEVFYLLKKYGKTITAAESLTAGLFQASVADFPGASQVFKGGFVTYSMEEKAKM
LGIPLSKLEEHGVVSHFTAEKMAEGARVKTDSDYGIALTGVAGPDALEGHQAGTVFIGIADRNQVRSIKVVIGGRSRSDV
RYISTLYAFNLVRQALLQEGNSI

Nucleotide


Download         Length: 1272 bp        

>NTDB_id=1131973 H1W80_RS00355 WP_087009608.1 61915..63186(+) (cinA) [Streptococcus thermophilus isolate STH_CIRM_1125]
ATGAAAGCTGAATTGATTACAGTAGGAACTGAAATTCTTACAGGGCAAATCACCAATACCAATGCCCAATTTTTATCTGA
AAAACTAGCTGAATTAGGAATTGACGTGTATTTTCACACAGCGGTAGGAGACAATGAAAACCGTCTACTTTCAGTCTTAG
ACCAGTCTAGTAAACGTAGCGATTTAGTCATACTCTGTGGAGGACTTGGCCCTACTGAGGATGACTTAACCAAACAAACA
TTGGCTAAGTTTTTAGGCAAAGAACTCATTTTTGATGAGGAGGCAAGTAAAAAACTGGATAGTTTCTTTGCTACTCGTCC
TAAACATACACGAACGCCTAATAATGAACGCCAAGCGCAAATTGTTGAGGGGGCTGTCCCCTTGCAAAATCTCACAGGTC
TGGCAGTTGGAGGAATTATTACTGTTGAAGGAGTGACCTATGTTGTCTTGCCTGGTCCGCCAAGTGAACTCAAACCTATG
GTGAACCAAGAGCTTATTCCAGCTCTTACAGAGAATCATACTACGCTTCATTCTAGAGTCCTAAGGTTTTTTGGTGTTGG
AGAAAGTCAATTGGTGACTATTATTAAAGATCTCATTGTTAACCAAACAGACCCAACCATTGCGCCCTATGCTAAAGTGG
GAGAAGTGACCCTTCGCTTATCAACAAAGGCATCGTCGCAAGAAGAAGCGGATCGAAAACTAGATGTTTTAGAAGAACAA
ATTCGTTCTACTAAAACTCTAGATGGAAAAAGCTTGTCTGATCTCATCTATGGATATGGAGAATCAAATAGCTTAGCTTA
TGAAGTGTTCTATTTGCTTAAGAAATATGGCAAAACTATTACTGCAGCTGAAAGTTTAACAGCTGGCTTATTTCAAGCTA
GTGTTGCTGATTTTCCTGGAGCTTCACAAGTATTCAAGGGTGGTTTTGTCACCTATAGCATGGAAGAAAAAGCTAAAATG
TTGGGTATTCCCTTATCTAAATTAGAAGAGCATGGTGTTGTTAGTCATTTTACAGCAGAAAAAATGGCTGAGGGTGCCCG
AGTTAAGACAGATAGTGATTACGGAATTGCGCTTACTGGAGTAGCAGGACCAGATGCTTTGGAAGGGCATCAAGCAGGTA
CAGTCTTTATTGGTATTGCCGATAGAAACCAAGTGCGGTCAATTAAGGTTGTTATAGGTGGAAGAAGTCGATCTGATGTT
AGATATATCAGTACACTCTATGCCTTTAACCTAGTTCGCCAAGCTTTATTACAAGAGGGCAACTCAATTTAA

Domains

Predicted by InterproScan.

Competence-damaged protein (CinA)

(264-415)

Damage-inducible protein CinA KH domain (CinA_KH)

(178-243)

Probable molybdopterin binding domain (MoCF_biosynth)

(5-170)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  cinA Streptococcus mitis SK321

74.224

99.054

0.735
  cinA Streptococcus mitis NCTC 12261

73.508

99.054

0.728
  cinA Streptococcus pneumoniae TIGR4

71.838

99.054

0.712
  cinA Streptococcus pneumoniae Rx1

71.599

99.054

0.709
  cinA Streptococcus pneumoniae R6

71.599

99.054

0.709
  cinA Streptococcus pneumoniae D39

71.36

99.054

0.707
  cinA Streptococcus mutans UA159

69.834

99.527

0.695
  cinA Streptococcus suis isolate S10

54.087

98.345

0.532
  cinA Bacillus subtilis subsp. subtilis str. 168

44.418

99.527

0.442

Multiple sequence alignment