Detailed information    

insolico Bioinformatically predicted

Overview

Name   cinA   Type   Machinery gene
Locus tag   H1W87_RS00355 Genome accession   NZ_LR822037
Coordinates   61888..63159 (+) Length   423 a.a.
NCBI ID   WP_011225285.1    Uniprot ID   Q5M6H3
Organism   Streptococcus thermophilus isolate STH_CIRM_1121     
Function   facilitate localization of RecA (predicted from homology)   
Homologous recombination

Genomic Context

Location: 56888..68159
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  H1W87_RS00325 (STHERMO_0060) - 57226..57614 (-) 389 Protein_43 LytTR family DNA-binding domain-containing protein -
  H1W87_RS00330 (STHERMO_0061) - 57838..58143 (+) 306 WP_002949050.1 hypothetical protein -
  H1W87_RS00335 (STHERMO_0062) mutL 58195..60138 (+) 1944 WP_011225282.1 DNA mismatch repair endonuclease MutL -
  H1W87_RS00340 (STHERMO_0063) - 60268..60489 (+) 222 WP_041826940.1 hypothetical protein -
  H1W87_RS00345 (STHERMO_0064) ruvA 60641..61231 (+) 591 WP_011680603.1 Holliday junction branch migration protein RuvA -
  H1W87_RS00350 (STHERMO_0065) - 61238..61792 (+) 555 WP_011225284.1 DNA-3-methyladenine glycosylase I -
  H1W87_RS00355 (STHERMO_0066) cinA 61888..63159 (+) 1272 WP_011225285.1 competence/damage-inducible protein A Machinery gene
  H1W87_RS00360 (STHERMO_0067) recA 63195..64349 (+) 1155 WP_002949056.1 recombinase RecA Machinery gene
  H1W87_RS00365 (STHERMO_0068) spx 64526..64924 (+) 399 WP_002949058.1 transcriptional regulator Spx -

Sequence

Protein


Download         Length: 423 a.a.        Molecular weight: 45984.33 Da        Isoelectric Point: 5.0042

>NTDB_id=1131859 H1W87_RS00355 WP_011225285.1 61888..63159(+) (cinA) [Streptococcus thermophilus isolate STH_CIRM_1121]
MKAELIAVGTEILTGQITNTNAQFLSEKLAELGIDVYFHTAVGDNENRLLSVLDQSSKRSDLVILCGGLGPTEDDLTKQT
LAKFLGKELIFDEEASKKLDSFFATRPKHTRTPNNERQAQIVEGAVPLQNLTGLAVGGIITVEGVTYVVLPGPPSELKPM
VNQELIPALTENHTTLYSRVLRFFGVGESQLVTIIKDLIVNQTDPTIAPYAKVGEVTLRLSTKASSQEEADRKLDVLEEQ
IRSTKTLDGKSLSDLIYGYGESNSLAYEVFYLLKKYGKTITAAESLTAGLFQASVADFPGASQVFKGGFVTYSMEEKAKM
LDIPLSKLEEHGVVSHFTAEKMAEGARVKTDSDYGIALTGVAGPDALEGHQAGTVFIGIADRNQVRSIKVVIGGRSRSDV
RYISTLYAFNLVRQALLQEDNSI

Nucleotide


Download         Length: 1272 bp        

>NTDB_id=1131859 H1W87_RS00355 WP_011225285.1 61888..63159(+) (cinA) [Streptococcus thermophilus isolate STH_CIRM_1121]
ATGAAAGCTGAATTGATTGCAGTAGGAACTGAAATTCTTACAGGGCAAATCACCAATACCAATGCCCAATTTTTATCTGA
AAAACTAGCTGAATTAGGAATTGACGTGTATTTTCACACAGCGGTAGGAGACAATGAAAACCGTCTACTTTCAGTCTTAG
ACCAGTCTAGTAAACGTAGCGATTTAGTCATACTCTGTGGAGGACTTGGCCCTACTGAGGATGACCTAACCAAACAAACA
TTGGCTAAGTTTTTAGGCAAAGAACTCATTTTTGATGAGGAGGCAAGTAAAAAACTGGATAGTTTCTTTGCTACTCGTCC
TAAACATACACGAACGCCTAATAATGAACGCCAAGCGCAAATTGTTGAGGGGGCTGTCCCCTTGCAAAATCTCACAGGTC
TGGCAGTTGGAGGAATTATTACTGTTGAAGGAGTGACCTATGTTGTCTTGCCTGGTCCGCCAAGTGAACTCAAACCTATG
GTGAACCAAGAGCTTATTCCAGCTCTTACAGAGAATCATACTACGCTTTATTCTAGAGTCCTAAGGTTTTTTGGTGTTGG
AGAAAGTCAATTGGTGACTATTATTAAAGATCTCATTGTTAACCAAACAGACCCAACCATTGCGCCCTATGCTAAAGTGG
GAGAAGTGACCCTTCGCTTATCAACAAAGGCATCGTCGCAAGAAGAAGCGGATCGAAAACTAGATGTTTTAGAAGAACAA
ATTCGTTCTACTAAAACTCTAGATGGAAAAAGCTTGTCTGATCTCATCTATGGATATGGAGAATCAAATAGCTTAGCTTA
TGAAGTGTTCTATTTGCTTAAGAAATATGGCAAAACTATTACTGCAGCTGAAAGTTTAACAGCTGGCTTATTTCAAGCTA
GTGTTGCTGATTTTCCTGGAGCTTCACAAGTATTCAAGGGTGGTTTTGTCACCTATAGCATGGAAGAAAAAGCTAAAATG
TTGGATATTCCCTTATCTAAATTAGAAGAGCATGGTGTTGTTAGTCATTTTACAGCAGAAAAAATGGCTGAGGGTGCCCG
AGTTAAGACAGATAGTGATTACGGAATTGCGCTTACTGGAGTAGCAGGACCAGATGCTTTGGAAGGGCATCAAGCAGGTA
CAGTCTTTATTGGTATTGCCGATAGAAACCAAGTGCGGTCAATTAAGGTTGTTATAGGTGGAAGAAGTCGATCTGATGTT
AGATATATCAGTACACTCTATGCCTTTAACCTAGTTCGCCAAGCTTTATTACAAGAGGACAACTCAATTTAA

Domains

Predicted by InterproScan.

Probable molybdopterin binding domain (MoCF_biosynth)

(5-170)

Competence-damaged protein (CinA)

(264-415)

Damage-inducible protein CinA KH domain (CinA_KH)

(178-243)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q5M6H3

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  cinA Streptococcus mitis SK321

74.94

99.054

0.742
  cinA Streptococcus mitis NCTC 12261

73.747

99.054

0.73
  cinA Streptococcus pneumoniae TIGR4

72.554

99.054

0.719
  cinA Streptococcus pneumoniae Rx1

72.315

99.054

0.716
  cinA Streptococcus pneumoniae R6

72.315

99.054

0.716
  cinA Streptococcus pneumoniae D39

72.076

99.054

0.714
  cinA Streptococcus mutans UA159

70.071

99.527

0.697
  cinA Streptococcus suis isolate S10

54.327

98.345

0.534
  cinA Bacillus subtilis subsp. subtilis str. 168

44.418

99.527

0.442

Multiple sequence alignment