Detailed information    

insolico Bioinformatically predicted

Overview

Name   cinA   Type   Machinery gene
Locus tag   H1W95_RS00410 Genome accession   NZ_LR822030
Coordinates   70745..72016 (+) Length   423 a.a.
NCBI ID   WP_180483444.1    Uniprot ID   A0AAU9HEM6
Organism   Streptococcus thermophilus isolate STH_CIRM_1046     
Function   facilitate localization of RecA (predicted from homology)   
Homologous recombination

Genomic Context

Location: 65745..77016
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  H1W95_RS00380 (STHERMO_0072) - 66080..66471 (-) 392 Protein_54 LytTR family DNA-binding domain-containing protein -
  H1W95_RS00385 (STHERMO_0073) - 66695..67000 (+) 306 WP_002949050.1 hypothetical protein -
  H1W95_RS00390 (STHERMO_0074) mutL 67052..68995 (+) 1944 WP_014607839.1 DNA mismatch repair endonuclease MutL -
  H1W95_RS00395 (STHERMO_0075) - 69125..69346 (+) 222 WP_002949052.1 hypothetical protein -
  H1W95_RS00400 (STHERMO_0076) ruvA 69498..70088 (+) 591 WP_011680603.1 Holliday junction branch migration protein RuvA -
  H1W95_RS00405 (STHERMO_0077) - 70095..70649 (+) 555 WP_011680604.1 DNA-3-methyladenine glycosylase I -
  H1W95_RS00410 (STHERMO_0078) cinA 70745..72016 (+) 1272 WP_180483444.1 competence/damage-inducible protein A Machinery gene
  H1W95_RS00415 (STHERMO_0079) recA 72052..73206 (+) 1155 WP_002949056.1 recombinase RecA Machinery gene
  H1W95_RS00420 (STHERMO_0080) spx 73383..73781 (+) 399 WP_002949058.1 transcriptional regulator Spx -

Sequence

Protein


Download         Length: 423 a.a.        Molecular weight: 45824.18 Da        Isoelectric Point: 5.0948

>NTDB_id=1131437 H1W95_RS00410 WP_180483444.1 70745..72016(+) (cinA) [Streptococcus thermophilus isolate STH_CIRM_1046]
MKAELIAVGTEILTGQITNTNAQFLSEKLAELGIDVYFHTAVGDNENRLLSVLDQSSKRSDLVILCGGLGPTEDDLTKQT
LAKFLGKELIFDEEASKKLDSFFATRPKHTRTPNNERQAQIVEGAVPLQNLTGLAVGGIITVEGVTYVVLPGPPSELKPM
VNQELIPALTENHTTLYSRVLRFFGVGESQLVTIIKDLIVNQTDPTIAPYAKVGEGTLRLSTKASSQEEADRKLDVLEEQ
IRSTKTLDGKSLSDLIYGYGESNSLAYEVFYLLKKYGKTITAAESLTAGLFQASVADFPGASQVFKGGFVTYSMEEKAKM
LGIPLSKLEEHGVVSHFTAEKMAEGARVKTDSDYGIALTGVAGPDALEGHQAGTVFIGIADRNQVRSIKVVIGGRSRSDV
RCISTLYAFNLVRQALLQEDNSI

Nucleotide


Download         Length: 1272 bp        

>NTDB_id=1131437 H1W95_RS00410 WP_180483444.1 70745..72016(+) (cinA) [Streptococcus thermophilus isolate STH_CIRM_1046]
ATGAAAGCTGAATTGATTGCAGTAGGAACTGAAATTCTTACAGGGCAAATCACCAATACCAATGCCCAATTTTTATCTGA
AAAACTAGCTGAATTAGGAATTGACGTGTATTTTCACACAGCGGTAGGAGACAATGAAAACCGTCTACTTTCAGTCTTAG
ACCAGTCTAGTAAACGTAGCGATTTAGTCATACTCTGTGGAGGACTTGGCCCTACTGAGGATGACCTAACCAAACAAACA
TTGGCTAAGTTTTTAGGCAAAGAACTCATTTTTGATGAGGAGGCAAGTAAAAAACTGGATAGTTTCTTTGCTACTCGTCC
TAAACATACACGAACGCCTAATAATGAACGCCAAGCGCAAATTGTTGAGGGGGCTGTCCCCTTGCAAAATCTCACAGGTC
TGGCAGTTGGAGGAATTATTACTGTTGAAGGAGTGACCTATGTTGTCTTGCCTGGTCCGCCAAGTGAACTCAAACCTATG
GTGAACCAAGAGCTTATTCCAGCTCTTACAGAGAATCATACTACGCTTTATTCTAGAGTCCTAAGGTTTTTTGGTGTTGG
AGAAAGTCAATTGGTGACTATTATTAAAGATCTCATTGTTAACCAAACAGACCCAACCATTGCGCCCTATGCTAAAGTGG
GAGAAGGGACCCTTCGCTTATCAACAAAGGCATCGTCGCAAGAAGAAGCGGATCGAAAACTAGATGTTTTAGAAGAACAA
ATTCGTTCTACTAAAACTCTAGATGGAAAAAGCTTGTCTGATCTCATCTATGGATATGGAGAATCAAATAGCTTAGCTTA
TGAAGTGTTCTATTTGCTTAAGAAATATGGCAAAACTATTACTGCAGCTGAAAGTTTAACAGCTGGCTTATTTCAAGCTA
GTGTTGCTGATTTTCCTGGAGCTTCACAAGTATTCAAGGGTGGTTTTGTCACCTATAGCATGGAAGAAAAAGCTAAAATG
TTGGGTATTCCCTTATCTAAATTAGAAGAGCATGGTGTTGTTAGTCATTTTACAGCAGAAAAAATGGCTGAGGGTGCCCG
AGTTAAGACAGATAGTGATTACGGAATTGCGCTTACTGGAGTAGCAGGACCAGATGCTTTGGAAGGGCATCAAGCAGGTA
CAGTCTTTATTGGTATTGCCGATAGAAACCAAGTGCGATCAATTAAGGTTGTTATAGGTGGAAGAAGTCGATCTGATGTT
AGATGTATCAGTACACTCTATGCCTTTAACCTAGTTCGCCAAGCTTTATTACAAGAGGACAACTCAATTTAA

Domains

Predicted by InterproScan.

Probable molybdopterin binding domain (MoCF_biosynth)

(5-170)

Competence-damaged protein (CinA)

(264-415)

Damage-inducible protein CinA KH domain (CinA_KH)

(178-243)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  cinA Streptococcus mitis SK321

74.463

99.054

0.738
  cinA Streptococcus mitis NCTC 12261

73.27

99.054

0.726
  cinA Streptococcus pneumoniae TIGR4

72.076

99.054

0.714
  cinA Streptococcus pneumoniae Rx1

71.838

99.054

0.712
  cinA Streptococcus pneumoniae R6

71.838

99.054

0.712
  cinA Streptococcus pneumoniae D39

71.599

99.054

0.709
  cinA Streptococcus mutans UA159

69.504

100

0.695
  cinA Streptococcus suis isolate S10

54.327

98.345

0.534
  cinA Bacillus subtilis subsp. subtilis str. 168

44.418

99.527

0.442

Multiple sequence alignment