Detailed information    

insolico Bioinformatically predicted

Overview

Name   comYB   Type   Machinery gene
Locus tag   H1W89_RS08720 Genome accession   NZ_LR822029
Coordinates   1673255..1674355 (-) Length   366 a.a.
NCBI ID   WP_116920398.1    Uniprot ID   -
Organism   Streptococcus thermophilus isolate STH_CIRM_1035     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1668255..1679355
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  H1W89_RS10055 (STHERMO_1933) - 1668580..1668855 (-) 276 WP_011681681.1 hypothetical protein -
  H1W89_RS08680 (STHERMO_1934) - 1668867..1669064 (-) 198 WP_011681682.1 helix-turn-helix transcriptional regulator -
  H1W89_RS08685 (STHERMO_1935) - 1669313..1670506 (-) 1194 WP_014608740.1 acetate kinase -
  H1W89_RS08690 (STHERMO_1936) comYH 1670562..1671518 (-) 957 WP_011226622.1 class I SAM-dependent methyltransferase Machinery gene
  H1W89_RS08695 (STHERMO_1937) comGG 1671563..1671880 (-) 318 WP_180474625.1 competence type IV pilus minor pilin ComGG -
  H1W89_RS08700 (STHERMO_1938) comYF 1671858..1672295 (-) 438 WP_014608742.1 competence type IV pilus minor pilin ComGF Machinery gene
  H1W89_RS08705 (STHERMO_1939) comGE 1672279..1672572 (-) 294 WP_011226625.1 competence type IV pilus minor pilin ComGE -
  H1W89_RS08710 (STHERMO_1940) comYD 1672544..1672972 (-) 429 WP_011226626.1 competence type IV pilus minor pilin ComGD Machinery gene
  H1W89_RS08715 (STHERMO_1941) comYC 1672932..1673258 (-) 327 WP_002946126.1 competence type IV pilus major pilin ComGC Machinery gene
  H1W89_RS08720 (STHERMO_1942) comYB 1673255..1674355 (-) 1101 WP_116920398.1 competence type IV pilus assembly protein ComGB Machinery gene
  H1W89_RS08725 (STHERMO_1943) comGA/cglA/cilD 1674237..1675178 (-) 942 WP_014608745.1 competence type IV pilus ATPase ComGA Machinery gene
  H1W89_RS08730 (STHERMO_1944) - 1675259..1675621 (-) 363 WP_014608746.1 DUF1033 family protein -

Sequence

Protein


Download         Length: 366 a.a.        Molecular weight: 41797.91 Da        Isoelectric Point: 10.1084

>NTDB_id=1131431 H1W89_RS08720 WP_116920398.1 1673255..1674355(-) (comYB) [Streptococcus thermophilus isolate STH_CIRM_1035]
MPEKISKTIRRPTGISSWKVWLNKDVSLRGISKGKKLKISQQVKVIQLFKQLLKAGFTLTEIVAFLERSHLLKEASLSLM
KESLIRGDRLDQMLALVGFSDNIVTQISLADKHGNLLGSLTKIETYMLRMTKVRKKLMEVATYPILLLGFLILIMLGLKN
YLLPQLLEGDGKNNWAVQLVQIFPQLFFVSLCGLLVLGLILYLWVKRQSALVFYRRMAKIPFIGQTVRLYTTAYYAREWG
NLLGQGVDLLDLVALMQEQKSKLFRELGADLEEALMLGQSFPERIASHPFFTKELSLIIAYGEANARLGYELEVYAEEVW
QNFFNRLNKATTFVQPLIFVIVAVVIVMIYVAMLLPMYQNMEGMMS

Nucleotide


Download         Length: 1101 bp        

>NTDB_id=1131431 H1W89_RS08720 WP_116920398.1 1673255..1674355(-) (comYB) [Streptococcus thermophilus isolate STH_CIRM_1035]
TTGCCAGAGAAAATTTCCAAAACCATTCGTCGACCAACTGGAATCAGCAGTTGGAAGGTTTGGTTAAACAAGGATGTCTC
ACTGAGAGGGATATCCAAGGGGAAAAAATTAAAGATTAGTCAGCAAGTTAAGGTTATCCAGCTCTTCAAACAACTTTTAA
AGGCCGGTTTTACCTTAACTGAAATCGTAGCCTTTTTGGAGCGAAGTCACTTGCTGAAAGAAGCATCCTTGTCTCTTATG
AAAGAGAGTTTAATACGCGGTGATAGGTTGGATCAGATGTTAGCGTTAGTGGGGTTTTCGGACAATATTGTTACTCAGAT
TTCTCTTGCTGACAAGCACGGTAATCTTCTAGGGAGTCTAACAAAGATTGAAACCTATATGCTTCGTATGACAAAGGTTC
GCAAGAAACTCATGGAGGTGGCGACTTATCCCATACTACTTCTGGGTTTTCTGATTCTGATTATGCTAGGACTTAAAAAT
TATCTTCTACCCCAACTCTTAGAGGGTGATGGTAAGAATAATTGGGCTGTACAGTTGGTTCAAATTTTTCCCCAGCTTTT
TTTTGTGAGTTTGTGTGGACTCCTTGTGTTGGGTTTAATTCTCTATCTATGGGTGAAACGACAGTCAGCCCTTGTTTTTT
ATAGGCGAATGGCCAAAATCCCTTTTATTGGTCAGACAGTAAGGCTTTACACGACCGCCTATTATGCTAGGGAATGGGGA
AATTTATTAGGTCAAGGCGTTGATTTGCTAGATTTGGTGGCTCTTATGCAAGAGCAAAAGTCTAAACTCTTCCGTGAGCT
GGGAGCCGATTTGGAAGAAGCCCTGATGCTGGGACAGAGTTTTCCAGAACGTATTGCCAGTCATCCGTTTTTTACTAAGG
AGCTCTCACTAATTATTGCTTATGGGGAGGCCAATGCGAGGTTGGGATATGAGTTGGAAGTTTATGCCGAGGAGGTTTGG
CAAAACTTCTTTAACCGTCTTAATAAGGCAACAACCTTTGTGCAACCCCTCATTTTTGTTATTGTTGCAGTTGTGATTGT
AATGATCTATGTAGCCATGCTATTACCAATGTATCAAAATATGGAAGGAATGATGTCATGA

Domains

Predicted by InterproScan.

Type II secretion system (T2SS), protein F (T2SSF)

(236-356)

Type II secretion system (T2SS), protein F (T2SSF)

(51-164)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comYB Streptococcus mutans UA140

54.678

93.443

0.511
  comYB Streptococcus mutans UA159

54.678

93.443

0.511
  comYB Streptococcus gordonii str. Challis substr. CH1

51.17

93.443

0.478
  comGB/cglB Streptococcus mitis NCTC 12261

50.453

90.437

0.456
  comGB/cglB Streptococcus mitis SK321

49.697

90.164

0.448
  comGB/cglB Streptococcus pneumoniae Rx1

49.695

89.617

0.445
  comGB/cglB Streptococcus pneumoniae D39

49.695

89.617

0.445
  comGB/cglB Streptococcus pneumoniae R6

49.695

89.617

0.445
  comGB/cglB Streptococcus pneumoniae TIGR4

49.695

89.617

0.445
  comGB Lactococcus lactis subsp. cremoris KW2

45.758

90.164

0.413

Multiple sequence alignment