Detailed information NTG1131428

Bioinformatically predicted

Overview

• Name: comYF
• Type: Machinery gene
• Locus tag: H1W89_RS08700
• Genome accession: NZ_LR822029
• Coordinates: 1671858..1672295 (-)
• Length: 145 a.a.
• NCBI ID: WP_014608742.1
• Uniprot ID: -
• Organism: Streptococcus thermophilus isolate STH_CIRM_1035
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1666858..1677295

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
H1W89_RS08665 (STHERMO_1930)	-	1666922..1667584 (-)	663	WP_011681679.1	CPBP family intramembrane glutamic endopeptidase	-
H1W89_RS08670 (STHERMO_1931)	-	1667681..1668124 (-)	444	WP_180474624.1	CAAX protease	-
H1W89_RS10050 (STHERMO_1932)	-	1668198..1668536 (-)	339	WP_224103197.1	CPBP family intramembrane glutamic endopeptidase	-
H1W89_RS10055 (STHERMO_1933)	-	1668580..1668855 (-)	276	WP_011681681.1	hypothetical protein	-
H1W89_RS08680 (STHERMO_1934)	-	1668867..1669064 (-)	198	WP_011681682.1	helix-turn-helix transcriptional regulator	-
H1W89_RS08685 (STHERMO_1935)	-	1669313..1670506 (-)	1194	WP_014608740.1	acetate kinase	-
H1W89_RS08690 (STHERMO_1936)	comYH	1670562..1671518 (-)	957	WP_011226622.1	class I SAM-dependent methyltransferase	Machinery gene
H1W89_RS08695 (STHERMO_1937)	comGG	1671563..1671880 (-)	318	WP_180474625.1	competence type IV pilus minor pilin ComGG	-
H1W89_RS08700 (STHERMO_1938)	comYF	1671858..1672295 (-)	438	WP_014608742.1	competence type IV pilus minor pilin ComGF	Machinery gene
H1W89_RS08705 (STHERMO_1939)	comGE	1672279..1672572 (-)	294	WP_011226625.1	competence type IV pilus minor pilin ComGE	-
H1W89_RS08710 (STHERMO_1940)	comYD	1672544..1672972 (-)	429	WP_011226626.1	competence type IV pilus minor pilin ComGD	Machinery gene
H1W89_RS08715 (STHERMO_1941)	comYC	1672932..1673258 (-)	327	WP_002946126.1	competence type IV pilus major pilin ComGC	Machinery gene
H1W89_RS08720 (STHERMO_1942)	comYB	1673255..1674355 (-)	1101	WP_116920398.1	competence type IV pilus assembly protein ComGB	Machinery gene
H1W89_RS08725 (STHERMO_1943)	comGA/cglA/cilD	1674237..1675178 (-)	942	WP_014608745.1	competence type IV pilus ATPase ComGA	Machinery gene
H1W89_RS08730 (STHERMO_1944)	-	1675259..1675621 (-)	363	WP_014608746.1	DUF1033 family protein	-

Sequence

Protein

• Length: 145 a.a.
• Molecular weight: 16505.05 Da
• Isoelectric Point: 8.9784

>NTDB_id=1131428 H1W89_RS08700 WP_014608742.1 1671858..1672295(-) (comYF) [Streptococcus thermophilus isolate STH_CIRM_1035]
MYLSSKLRAFTLLECLVALLVIAGSVQVYQGLTTVLVSNVKQVRQQENQDWLLFVQQMEAELEGCQLVKVEWNKLYVKKD
NQDLAFGLSSASDFRKTNADGRGYQPMLFDVKSSKVSQKNQIVTIQVTLKNELQRSFVYAFEKTG

Nucleotide

• Length: 438 bp

>NTDB_id=1131428 H1W89_RS08700 WP_014608742.1 1671858..1672295(-) (comYF) [Streptococcus thermophilus isolate STH_CIRM_1035]
ATGTATCTAAGCAGTAAGCTGCGTGCCTTTACCCTCTTGGAATGTCTAGTGGCCTTGTTGGTCATTGCTGGCTCAGTTCA
AGTTTATCAAGGGTTAACCACTGTACTTGTGAGTAATGTTAAGCAGGTAAGACAACAAGAAAACCAAGATTGGCTTCTAT
TTGTTCAACAAATGGAGGCAGAATTAGAAGGATGTCAGTTGGTCAAGGTAGAGTGGAACAAACTCTATGTCAAGAAGGAT
AATCAAGACTTGGCTTTTGGTCTTTCAAGTGCCTCTGATTTTCGAAAAACAAATGCTGATGGTCGAGGTTATCAACCAAT
GCTTTTCGATGTCAAATCTAGTAAGGTAAGTCAAAAGAACCAGATAGTTACCATCCAAGTGACTCTTAAAAATGAACTAC
AAAGGAGTTTTGTTTATGCTTTTGAAAAAACAGGTTAG

Domains

Predicted by InterproScan.

• Putative Competence protein ComGF (ComGF) (39-134)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comYF	Streptococcus mutans UA140	58.865	97.241	0.572
comYF	Streptococcus mutans UA159	58.156	97.241	0.566
comGF/cglF	Streptococcus pneumoniae D39	47.857	96.552	0.462
comGF/cglF	Streptococcus pneumoniae Rx1	47.857	96.552	0.462
comGF/cglF	Streptococcus pneumoniae R6	47.857	96.552	0.462
comGF/cglF	Streptococcus pneumoniae TIGR4	47.857	96.552	0.462
comGF/cglF	Streptococcus mitis NCTC 12261	46.099	97.241	0.448
comGF/cglF	Streptococcus mitis SK321	45.39	97.241	0.441
comGF	Lactococcus lactis subsp. cremoris KW2	46.043	95.862	0.441