Detailed information    

insolico Bioinformatically predicted

Overview

Name   comEA   Type   Machinery gene
Locus tag   H1X08_RS02300 Genome accession   NZ_LR822025
Coordinates   431794..432489 (+) Length   231 a.a.
NCBI ID   WP_180482451.1    Uniprot ID   -
Organism   Streptococcus thermophilus isolate STH_CIRM_961     
Function   dsDNA binding to the cell surface (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 426794..437489
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  H1X08_RS02280 (STHERMO_0497) - 428806..429075 (-) 270 WP_180482448.1 GIY-YIG nuclease family protein -
  H1X08_RS02285 (STHERMO_0498) - 429079..429843 (-) 765 WP_180482449.1 tRNA1(Val) (adenine(37)-N6)-methyltransferase -
  H1X08_RS11205 - 429893..430802 (-) 910 Protein_416 polysaccharide deacetylase family protein -
  H1X08_RS02295 (STHERMO_0501) - 430932..431687 (+) 756 WP_180482450.1 lysophospholipid acyltransferase family protein -
  H1X08_RS02300 (STHERMO_0502) comEA 431794..432489 (+) 696 WP_180482451.1 helix-hairpin-helix domain-containing protein Machinery gene
  H1X08_RS02305 (STHERMO_0503) comEC/celB 432479..434719 (+) 2241 WP_179972172.1 DNA internalization-related competence protein ComEC/Rec2 Machinery gene
  H1X08_RS02310 (STHERMO_0504) - 434805..436067 (+) 1263 WP_179972171.1 UDP-N-acetylglucosamine 1-carboxyvinyltransferase -
  H1X08_RS02315 - 436133..436678 (+) 546 Protein_421 GNAT family N-acetyltransferase -

Sequence

Protein


Download         Length: 231 a.a.        Molecular weight: 24514.52 Da        Isoelectric Point: 4.6300

>NTDB_id=1131196 H1X08_RS02300 WP_180482451.1 431794..432489(+) (comEA) [Streptococcus thermophilus isolate STH_CIRM_961]
MKEKILAYVKDNRLFVSVIAVLMVIFCFFLWMTCGAGNSMEAETSYTDMTALSTSSSKQSSQSLSEASSQSKTEGSEKVK
SKVTVDVKGAVVNPGVYTLKAGARVTDVIQEAGGMTEDADAKSVNLAASLSDEEVIYVANKDENVSVLDQTGTGQVSDKG
GQAVSKDGKINLNIATSEQLQTISGIGAKRAEDVIAYRESHGGFQSVDDLKNVSGIGDKTLDKIRESLYVA

Nucleotide


Download         Length: 696 bp        

>NTDB_id=1131196 H1X08_RS02300 WP_180482451.1 431794..432489(+) (comEA) [Streptococcus thermophilus isolate STH_CIRM_961]
GTGAAGGAAAAGATTCTAGCCTATGTTAAAGATAATCGTCTGTTTGTGAGTGTCATCGCTGTACTGATGGTGATTTTTTG
CTTCTTTTTATGGATGACTTGTGGTGCCGGCAATAGCATGGAGGCGGAGACGTCTTATACAGATATGACAGCTTTGTCAA
CGTCTTCATCCAAACAAAGTTCACAGTCTCTTTCTGAGGCGTCTTCCCAGTCAAAGACCGAAGGAAGTGAAAAAGTTAAG
TCAAAAGTAACGGTAGATGTTAAGGGGGCTGTGGTCAATCCAGGTGTCTATACGCTAAAGGCAGGCGCTAGGGTGACAGA
TGTCATTCAGGAAGCTGGAGGAATGACAGAAGATGCAGACGCTAAGAGTGTTAACTTAGCCGCAAGCTTATCAGATGAAG
AGGTTATTTATGTAGCCAATAAAGATGAAAATGTTTCTGTCCTTGATCAAACAGGTACTGGTCAGGTCTCTGACAAAGGA
GGGCAGGCTGTATCTAAGGATGGCAAAATTAACTTAAATATAGCGACCTCAGAGCAGTTGCAAACCATTTCTGGAATTGG
AGCTAAGCGGGCAGAGGATGTCATTGCCTATCGTGAAAGTCATGGCGGCTTTCAGTCCGTAGATGACTTGAAAAATGTCT
CAGGAATTGGTGATAAAACATTAGATAAAATCAGAGAGTCCCTCTATGTGGCTTAA

Domains

Predicted by InterproScan.

Helix-hairpin-helix motif (HHH_3)

(167-228)

SLBB domain (SLBB)

(85-138)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comEA Streptococcus thermophilus LMD-9

99.134

100

0.991
  comEA/celA/cilE Streptococcus mitis SK321

39.474

98.701

0.39
  comEA/celA/cilE Streptococcus pneumoniae D39

39.035

98.701

0.385
  comEA/celA/cilE Streptococcus pneumoniae R6

39.035

98.701

0.385
  comEA/celA/cilE Streptococcus pneumoniae Rx1

39.035

98.701

0.385
  comEA/celA/cilE Streptococcus pneumoniae TIGR4

39.035

98.701

0.385
  comEA/celA/cilE Streptococcus mitis NCTC 12261

37.719

98.701

0.372

Multiple sequence alignment