Detailed information NTG1131197

Bioinformatically predicted

Overview

• Name: comEC/celB
• Type: Machinery gene
• Locus tag: H1X08_RS02305
• Genome accession: NZ_LR822025
• Coordinates: 432479..434719 (+)
• Length: 746 a.a.
• NCBI ID: WP_179972172.1
• Uniprot ID: -
• Organism: Streptococcus thermophilus isolate STH_CIRM_961
• Function: ssDNA transport into the cell (predicted from homology) DNA binding and uptake

Genomic Context

Location: 427479..439719

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
H1X08_RS02280 (STHERMO_0497)	-	428806..429075 (-)	270	WP_180482448.1	GIY-YIG nuclease family protein	-
H1X08_RS02285 (STHERMO_0498)	-	429079..429843 (-)	765	WP_180482449.1	tRNA1(Val) (adenine(37)-N6)-methyltransferase	-
H1X08_RS11205	-	429893..430802 (-)	910	Protein_416	polysaccharide deacetylase family protein	-
H1X08_RS02295 (STHERMO_0501)	-	430932..431687 (+)	756	WP_180482450.1	lysophospholipid acyltransferase family protein	-
H1X08_RS02300 (STHERMO_0502)	comEA	431794..432489 (+)	696	WP_180482451.1	helix-hairpin-helix domain-containing protein	Machinery gene
H1X08_RS02305 (STHERMO_0503)	comEC/celB	432479..434719 (+)	2241	WP_179972172.1	DNA internalization-related competence protein ComEC/Rec2	Machinery gene
H1X08_RS02310 (STHERMO_0504)	-	434805..436067 (+)	1263	WP_179972171.1	UDP-N-acetylglucosamine 1-carboxyvinyltransferase	-
H1X08_RS02315	-	436133..436678 (+)	546	Protein_421	GNAT family N-acetyltransferase	-
H1X08_RS02320 (STHERMO_0507)	spxR	436671..437951 (+)	1281	WP_179972170.1	CBS-HotDog domain-containing transcription factor SpxR	-
H1X08_RS02325 (STHERMO_0508)	-	437995..438855 (+)	861	WP_002951571.1	methionyl aminopeptidase	-

Sequence

Protein

• Length: 746 a.a.
• Molecular weight: 84981.00 Da
• Isoelectric Point: 9.9593

>NTDB_id=1131197 H1X08_RS02305 WP_179972172.1 432479..434719(+) (comEC/celB) [Streptococcus thermophilus isolate STH_CIRM_961]
MWLKKAPINLFSLALLIVALYFTIFVSNFYAIGTFVFLMICFLRHHWKNRAALKLVGLIGGFFLVYFLFLYNIAIMQDKQ
APAEIHQVTLVADTLSVNGERLSAIGKSNGQTYRVFYRLKSDKEQHFFKTTSQTLVLKGKIKLSSATGQRNFQGFDYQSY
LASQGIYRIAQIERLEHVVTPKSISPIAFFHQLRRKALVHIQTHFPNPMRHYMTGLLFGYLDKEFDEQSQLYTSLGIIHL
FALSGMQVGFFLGWFRYGLLRLGLPKNYILAILLPFSIFYGLMTGWTASVLRSLIQSLLAECGIKKLNNMGITLLLFFLV
LPHFLLTVGGVLSCSYAFLLCLFNFEEMPSFKKSIYMSLVLSLGTLPFLTYYYGTFQPLSLILTAIFSLVFDSFLLPVLT
VLFTLSGMVIFSQFNPLFEWMEFFLTWIQSWGVQPLILGKPSLFQFVSMIFVLVLLFDFWKKPQFRISLLMIFSLLMVWV
KHPLINEVTVVDVGQGDSIFLRSMKGETVLIDVGGKVTFVSKEKWQEGSQTSNAEKTLIPYLQERGVSQIDYLVLTHTDT
DHIGDLEEVAKRFKIKEICVSKGALTKPSFAKRIRFLKRPVRTLKAGDKLTMMGSNLQVLYPNKIGDGGNNDSLVLYGKL
LGTSFLFTGDLEKEGEEELMASYPNLKVRVLKAGHHGSKGSSSEAFLDQLKPSLALVSAGENNRYKHPNDETLERFKERH
IKVLRTDLDGAIRFKGWFQLSSETVR

Nucleotide

• Length: 2241 bp

>NTDB_id=1131197 H1X08_RS02305 WP_179972172.1 432479..434719(+) (comEC/celB) [Streptococcus thermophilus isolate STH_CIRM_961]
ATGTGGCTTAAAAAAGCTCCAATCAATCTTTTTTCCCTAGCGCTTTTAATAGTTGCTCTTTATTTTACTATTTTTGTATC
TAATTTCTATGCTATTGGGACTTTTGTCTTTCTGATGATATGTTTTTTGAGGCATCATTGGAAGAATAGAGCAGCTCTAA
AGTTGGTGGGACTTATAGGTGGTTTCTTTTTGGTCTACTTTTTATTTTTATACAATATAGCTATCATGCAAGATAAACAA
GCTCCTGCTGAAATTCATCAGGTGACACTGGTTGCAGATACGCTCTCAGTTAATGGTGAGCGATTATCAGCAATCGGGAA
GTCAAATGGACAAACCTATCGGGTCTTTTACCGGCTAAAATCTGATAAGGAGCAGCATTTTTTTAAGACTACGAGTCAAA
CGCTTGTTTTAAAAGGAAAAATAAAGTTGTCCTCGGCAACTGGTCAACGTAATTTTCAAGGCTTTGATTATCAGTCTTAT
CTAGCTAGTCAGGGCATTTATAGGATTGCTCAGATTGAGCGTCTGGAACATGTCGTAACCCCAAAATCGATATCTCCAAT
AGCTTTTTTTCATCAATTGAGGAGGAAGGCTCTAGTTCATATTCAGACGCATTTTCCTAATCCGATGAGACACTACATGA
CAGGACTGCTCTTTGGGTATTTGGACAAGGAGTTTGATGAGCAGAGTCAACTCTACACTAGCTTGGGGATTATTCATCTT
TTTGCGCTATCGGGTATGCAGGTTGGATTTTTTCTTGGCTGGTTTCGCTATGGACTTCTCCGTTTGGGGCTTCCCAAAAA
TTATATCCTTGCTATCTTATTACCTTTTTCGATTTTCTATGGCTTAATGACTGGTTGGACGGCTTCGGTCTTACGTTCTT
TGATTCAAAGCCTCTTGGCTGAGTGTGGTATTAAAAAACTGAACAATATGGGCATAACGCTACTTCTATTTTTTCTAGTC
TTGCCTCATTTTCTTTTAACGGTAGGAGGTGTTTTAAGTTGTTCTTATGCCTTCTTGTTGTGTTTATTTAATTTTGAGGA
GATGCCGTCCTTTAAAAAGTCAATTTATATGAGTTTAGTATTGAGTCTTGGGACTTTGCCTTTTTTGACCTACTATTATG
GAACTTTTCAACCATTGAGTTTGATTCTGACGGCAATCTTCTCTCTAGTTTTTGATAGCTTTCTCTTACCTGTCTTAACA
GTACTTTTTACACTTTCAGGAATGGTAATTTTTTCTCAATTTAATCCACTTTTTGAATGGATGGAGTTCTTTTTGACTTG
GATACAATCTTGGGGAGTCCAGCCATTGATTTTAGGAAAACCTAGCTTGTTTCAGTTTGTCTCAATGATATTTGTATTGG
TTTTGCTCTTTGATTTTTGGAAAAAGCCTCAGTTTAGAATATCCCTCTTGATGATTTTTAGTCTTTTGATGGTCTGGGTC
AAACATCCTTTAATAAATGAAGTAACGGTGGTCGACGTTGGTCAAGGAGATAGTATTTTTTTAAGGAGTATGAAAGGTGA
GACGGTCCTAATAGATGTAGGTGGCAAGGTGACTTTCGTCTCTAAGGAAAAATGGCAAGAGGGGAGCCAGACGAGTAATG
CGGAGAAAACCTTAATTCCCTATTTACAGGAAAGGGGAGTGTCTCAAATTGACTATCTGGTTCTGACTCATACGGATACA
GATCATATTGGTGATTTGGAGGAAGTGGCTAAACGGTTTAAGATTAAGGAAATTTGTGTCAGTAAGGGGGCTTTGACTAA
GCCTAGTTTTGCCAAACGTATTCGATTTCTTAAACGTCCCGTTCGCACTTTAAAGGCTGGTGATAAGCTGACTATGATGG
GAAGTAACCTACAGGTTCTTTATCCTAATAAAATTGGTGATGGTGGTAACAATGATTCACTTGTTCTCTATGGAAAGTTA
TTGGGAACCAGTTTTTTGTTTACTGGTGATTTAGAAAAAGAAGGAGAGGAGGAATTAATGGCTAGCTATCCAAATTTAAA
AGTAAGGGTCCTAAAAGCAGGACATCACGGTTCTAAAGGCTCTTCATCAGAAGCTTTTTTGGATCAGCTAAAGCCATCAC
TTGCTCTTGTCTCAGCTGGTGAAAATAATCGTTATAAGCATCCAAATGATGAAACATTAGAGCGTTTCAAAGAACGTCAC
ATTAAGGTTTTACGCACAGACCTGGATGGTGCCATTCGGTTTAAGGGATGGTTCCAACTATCAAGTGAAACTGTCCGATA
A

Domains

Predicted by InterproScan.

• Domain of unknown function (DUF4131) (DUF4131) (29-170)

• Metallo-beta-lactamase superfamily (Lactamase_B) (492-699)

• Competence protein (Competence) (216-462)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comEC/celB	Streptococcus mitis NCTC 12261	48.193	100	0.483
comEC/celB	Streptococcus mitis SK321	46.791	100	0.469
comEC/celB	Streptococcus pneumoniae TIGR4	46.123	100	0.462
comEC/celB	Streptococcus pneumoniae Rx1	45.856	100	0.46
comEC/celB	Streptococcus pneumoniae D39	45.856	100	0.46
comEC/celB	Streptococcus pneumoniae R6	45.856	100	0.46
comEC	Lactococcus lactis subsp. cremoris KW2	44.69	97.185	0.434