Detailed information    

insolico Bioinformatically predicted

Overview

Name   cinA   Type   Machinery gene
Locus tag   H0514_RS00365 Genome accession   NZ_LR822020
Coordinates   63271..64542 (+) Length   423 a.a.
NCBI ID   WP_179972484.1    Uniprot ID   A0A7U7GZ68
Organism   Streptococcus thermophilus isolate STH_CIRM_956     
Function   facilitate localization of RecA (predicted from homology)   
Homologous recombination

Genomic Context

Location: 58271..69542
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  H0514_RS00335 (STHERMO_0062) - 58604..59041 (-) 438 WP_002886318.1 LytTR family DNA-binding domain-containing protein -
  H0514_RS00340 (STHERMO_0063) - 59220..59525 (+) 306 WP_179972482.1 hypothetical protein -
  H0514_RS00345 (STHERMO_0064) mutL 59577..61520 (+) 1944 WP_011680601.1 DNA mismatch repair endonuclease MutL -
  H0514_RS00350 (STHERMO_0065) - 61651..61872 (+) 222 WP_011680602.1 hypothetical protein -
  H0514_RS00355 (STHERMO_0066) ruvA 62024..62614 (+) 591 WP_111679083.1 Holliday junction branch migration protein RuvA -
  H0514_RS00360 (STHERMO_0067) - 62621..63175 (+) 555 WP_111679085.1 DNA-3-methyladenine glycosylase I -
  H0514_RS00365 (STHERMO_0068) cinA 63271..64542 (+) 1272 WP_179972484.1 competence/damage-inducible protein A Machinery gene
  H0514_RS00370 (STHERMO_0069) recA 64578..65717 (+) 1140 WP_179972485.1 recombinase RecA Machinery gene
  H0514_RS00375 (STHERMO_0070) spx 65894..66292 (+) 399 WP_179972486.1 transcriptional regulator Spx -

Sequence

Protein


Download         Length: 423 a.a.        Molecular weight: 45836.23 Da        Isoelectric Point: 5.2053

>NTDB_id=1131060 H0514_RS00365 WP_179972484.1 63271..64542(+) (cinA) [Streptococcus thermophilus isolate STH_CIRM_956]
MKAELIAVGTEILTGQITNTNAQFLSEKLAELGIDVYFHTAVGDNENRLLSVLDQSSKRSDLVILCGGLGPTEDDLTKQS
LAKFLGKELIFDEEASKKLDSFFATRPKHTRTPNNERQAQIVEGAVPLQNLTGLAVGGIITVEGVTYVVLPGPPSELKPM
VNRELIPALTENHTTLYSRVLRFFGVGESQLVTIIKDLIVNQTDPTIAPYAKVGEVTLRLSTKASSQEEADRKLDVLEEQ
IRSTKTLDGKSLSDLIYGYGESNSLAYEVFNLLKKYGKTITAAESLTAGLFQASVADFPGASQVFKGGFVTYSMEEKAKM
LGIPLSKLEEHGVVSHFTAEKMAEGARVKTGSDYGIALTGVAGPDALEGHQAGTVFIGIADRNQVRSIMVVIGGRSRSDV
RYISTLYAFNLVRQALLQEDNSI

Nucleotide


Download         Length: 1272 bp        

>NTDB_id=1131060 H0514_RS00365 WP_179972484.1 63271..64542(+) (cinA) [Streptococcus thermophilus isolate STH_CIRM_956]
ATGAAAGCTGAATTGATTGCAGTAGGAACTGAAATTCTTACAGGGCAAATCACCAATACCAATGCCCAATTTTTATCTGA
AAAACTAGCTGAATTAGGAATTGACGTGTATTTTCACACAGCGGTAGGAGACAATGAAAACCGTCTACTTTCAGTCTTAG
ACCAGTCTAGTAAACGTAGCGATTTAGTTATACTCTGTGGAGGACTTGGCCCTACTGAGGATGACTTAACCAAACAATCA
TTGGCTAAGTTTTTAGGCAAAGAACTCATTTTTGATGAGGAGGCAAGTAAAAAACTGGATAGTTTCTTTGCTACTCGTCC
TAAACATACACGAACGCCTAATAATGAACGCCAAGCGCAAATTGTTGAGGGGGCTGTCCCCTTGCAAAATCTCACAGGTC
TGGCAGTTGGAGGAATTATTACTGTTGAAGGAGTGACCTATGTTGTCTTGCCTGGTCCGCCAAGTGAACTCAAACCTATG
GTGAACCGAGAGCTTATTCCAGCTCTTACAGAGAATCATACTACGCTTTATTCTAGAGTCCTAAGGTTTTTTGGTGTTGG
AGAAAGTCAATTGGTGACTATTATTAAAGATCTCATTGTTAACCAAACAGACCCAACCATTGCGCCCTATGCTAAAGTGG
GAGAAGTGACCCTTCGCTTATCAACAAAGGCATCGTCGCAAGAAGAAGCGGATCGAAAACTAGATGTTTTAGAAGAACAA
ATTCGTTCTACTAAAACTCTAGATGGAAAAAGCTTGTCTGATCTCATCTATGGATATGGAGAATCAAATAGCTTAGCTTA
TGAAGTGTTTAATTTGCTTAAGAAATATGGCAAAACTATTACTGCAGCTGAAAGTTTAACAGCTGGCTTATTTCAAGCTA
GTGTTGCTGATTTTCCTGGAGCTTCACAAGTATTCAAGGGTGGTTTTGTCACCTATAGCATGGAAGAAAAAGCTAAAATG
TTGGGTATTCCCTTATCTAAATTAGAAGAGCATGGTGTTGTTAGTCATTTTACAGCAGAAAAAATGGCTGAGGGTGCCCG
AGTTAAGACAGGTAGTGATTACGGAATTGCGCTTACTGGAGTAGCAGGACCAGATGCTTTGGAAGGGCATCAAGCAGGTA
CAGTCTTTATTGGTATTGCCGATAGAAACCAAGTGAGGTCAATTATGGTTGTTATAGGTGGAAGAAGTCGATCTGATGTT
AGATATATCAGTACACTCTATGCCTTTAACCTAGTTCGCCAAGCTTTATTACAAGAGGACAACTCAATTTAA

Domains

Predicted by InterproScan.

Damage-inducible protein CinA KH domain (CinA_KH)

(178-243)

Probable molybdopterin binding domain (MoCF_biosynth)

(5-170)

Competence-damaged protein (CinA)

(264-415)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A7U7GZ68

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  cinA Streptococcus mitis SK321

74.224

99.054

0.735
  cinA Streptococcus mitis NCTC 12261

73.031

99.054

0.723
  cinA Streptococcus pneumoniae TIGR4

71.838

99.054

0.712
  cinA Streptococcus pneumoniae Rx1

71.599

99.054

0.709
  cinA Streptococcus pneumoniae R6

71.599

99.054

0.709
  cinA Streptococcus pneumoniae D39

71.36

99.054

0.707
  cinA Streptococcus mutans UA159

69.834

99.527

0.695
  cinA Streptococcus suis isolate S10

54.327

98.345

0.534
  cinA Bacillus subtilis subsp. subtilis str. 168

44.656

99.527

0.444

Multiple sequence alignment