Detailed information    

insolico Bioinformatically predicted

Overview

Name   comYB   Type   Machinery gene
Locus tag   H0511_RS08725 Genome accession   NZ_LR822017
Coordinates   1707831..1708931 (-) Length   366 a.a.
NCBI ID   WP_179974043.1    Uniprot ID   -
Organism   Streptococcus thermophilus isolate STH_CIRM_336     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1702831..1713931
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  H0511_RS10235 (STHERMO_1964) - 1703155..1703430 (-) 276 WP_011681681.1 hypothetical protein -
  H0511_RS08685 - 1703442..1703640 (-) 199 Protein_1681 helix-turn-helix transcriptional regulator -
  H0511_RS08690 (STHERMO_1966) - 1703889..1705082 (-) 1194 WP_014608740.1 acetate kinase -
  H0511_RS08695 (STHERMO_1967) comYH 1705138..1706094 (-) 957 WP_011226622.1 class I SAM-dependent methyltransferase Machinery gene
  H0511_RS08700 (STHERMO_1968) comGG 1706139..1706456 (-) 318 WP_011681685.1 competence type IV pilus minor pilin ComGG -
  H0511_RS08705 (STHERMO_1969) comYF 1706434..1706871 (-) 438 WP_179974042.1 competence type IV pilus minor pilin ComGF Machinery gene
  H0511_RS08710 (STHERMO_1970) comGE 1706855..1707148 (-) 294 WP_179972344.1 competence type IV pilus minor pilin ComGE -
  H0511_RS08715 (STHERMO_1971) comGD 1707120..1707548 (-) 429 WP_269473123.1 competence type IV pilus minor pilin ComGD -
  H0511_RS08720 (STHERMO_1972) comYC 1707508..1707834 (-) 327 WP_179972346.1 competence type IV pilus major pilin ComGC Machinery gene
  H0511_RS08725 (STHERMO_1973) comYB 1707831..1708931 (-) 1101 WP_179974043.1 competence type IV pilus assembly protein ComGB Machinery gene
  H0511_RS08730 (STHERMO_1974) comGA/cglA/cilD 1708813..1709754 (-) 942 WP_179974044.1 competence type IV pilus ATPase ComGA Machinery gene
  H0511_RS08735 (STHERMO_1975) - 1709835..1710197 (-) 363 WP_179972348.1 DUF1033 family protein -

Sequence

Protein


Download         Length: 366 a.a.        Molecular weight: 42003.13 Da        Isoelectric Point: 10.0647

>NTDB_id=1130994 H0511_RS08725 WP_179974043.1 1707831..1708931(-) (comYB) [Streptococcus thermophilus isolate STH_CIRM_336]
MPEKISKTIRRPTGIISWKVWLNKDVSLRGISKGKKLKISQQVKVIQLFKQLLKAGFTLTEIVAFLERSHLLKETSLSLM
KESLIRGDRLDQMFALVGFSDNIVTQISLADKHGNLLGSLTKIETYMLRMTKVRKKLMEVATYPILLIGFLILIMLGLKN
YLLPQLLEGDGRNNWAVQLVQIFPQLFFVNLCGFLVLGLILYLWVKRQSALVFYRRMAQIPFIGQIVRLYTTAYYAREWG
NLLGQGVDLLDLVALMQEQKSKLFRELGADLEEALMLGQSFPERIASHPFFTKELSLIIAYGEANARLGYELEVYAEEVW
QNFFNRLNKATTFVQPLIFVIIAVVIVMIYVAMLLPMYQNMEGMMS

Nucleotide


Download         Length: 1101 bp        

>NTDB_id=1130994 H0511_RS08725 WP_179974043.1 1707831..1708931(-) (comYB) [Streptococcus thermophilus isolate STH_CIRM_336]
TTGCCAGAGAAAATTTCCAAAACCATTCGTCGACCAACTGGAATCATCAGTTGGAAGGTTTGGTTAAACAAGGATGTCTC
ACTGAGAGGGATATCCAAGGGGAAAAAATTAAAGATTAGTCAGCAAGTTAAGGTTATCCAGCTCTTCAAACAACTTCTAA
AGGCCGGTTTTACCTTAACTGAAATCGTAGCCTTTTTGGAGCGAAGTCACTTGCTGAAAGAAACGTCCTTGTCTCTTATG
AAGGAGAGTTTAATACGCGGTGATAGGTTGGATCAGATGTTCGCGTTAGTGGGGTTTTCGGACAATATTGTTACTCAGAT
TTCTCTTGCTGACAAGCACGGTAATCTTCTAGGGAGTCTAACAAAGATTGAAACCTATATGCTTCGTATGACAAAGGTTC
GCAAGAAACTCATGGAGGTGGCGACTTATCCCATACTACTTATAGGTTTTCTGATTCTGATTATGCTAGGACTTAAAAAT
TATCTTCTACCCCAACTCTTAGAGGGTGATGGTAGGAATAATTGGGCTGTACAGTTGGTTCAAATTTTTCCTCAGCTCTT
TTTTGTGAATTTGTGTGGATTCCTTGTGTTGGGCTTAATTCTCTATCTATGGGTGAAACGACAGTCAGCCCTTGTTTTTT
ATAGGCGAATGGCCCAAATCCCTTTTATTGGTCAGATAGTAAGGCTTTACACGACCGCCTATTATGCTAGGGAATGGGGA
AATTTATTAGGTCAAGGCGTTGATTTGCTAGATTTGGTGGCTCTTATGCAAGAGCAAAAGTCTAAACTCTTCCGTGAGCT
GGGAGCCGATTTGGAAGAAGCCCTGATGCTGGGACAGAGTTTTCCTGAACGTATTGCCAGTCATCCGTTTTTTACTAAGG
AGCTCTCGCTAATTATTGCTTATGGAGAGGCCAATGCGAGGTTGGGCTATGAGTTGGAAGTTTATGCCGAGGAGGTTTGG
CAAAACTTCTTTAACCGTCTTAATAAGGCAACAACCTTTGTGCAACCCCTCATTTTTGTTATTATTGCAGTTGTGATTGT
GATGATCTATGTAGCCATGCTATTACCAATGTATCAAAATATGGAAGGAATGATGTCATGA

Domains

Predicted by InterproScan.

Type II secretion system (T2SS), protein F (T2SSF)

(236-356)

Type II secretion system (T2SS), protein F (T2SSF)

(51-164)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comYB Streptococcus mutans UA140

54.386

93.443

0.508
  comYB Streptococcus mutans UA159

54.386

93.443

0.508
  comYB Streptococcus gordonii str. Challis substr. CH1

50.292

93.443

0.47
  comGB/cglB Streptococcus mitis NCTC 12261

50.151

90.437

0.454
  comGB/cglB Streptococcus mitis SK321

49.091

90.164

0.443
  comGB/cglB Streptococcus pneumoniae Rx1

49.085

89.617

0.44
  comGB/cglB Streptococcus pneumoniae D39

49.085

89.617

0.44
  comGB/cglB Streptococcus pneumoniae R6

49.085

89.617

0.44
  comGB/cglB Streptococcus pneumoniae TIGR4

49.085

89.617

0.44
  comGB Lactococcus lactis subsp. cremoris KW2

43.465

89.891

0.391

Multiple sequence alignment