Detailed information NTG1130992

Bioinformatically predicted

Overview

• Name: comYF
• Type: Machinery gene
• Locus tag: H0511_RS08705
• Genome accession: NZ_LR822017
• Coordinates: 1706434..1706871 (-)
• Length: 145 a.a.
• NCBI ID: WP_179974042.1
• Uniprot ID: A0A8D6U885
• Organism: Streptococcus thermophilus isolate STH_CIRM_336
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1701434..1711871

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
H0511_RS08670 (STHERMO_1961)	-	1701497..1702159 (-)	663	WP_179974041.1	CPBP family intramembrane glutamic endopeptidase	-
H0511_RS08675 (STHERMO_1962)	-	1702256..1702699 (-)	444	WP_011681680.1	hypothetical protein	-
H0511_RS10230 (STHERMO_1963)	-	1702773..1703198 (-)	426	WP_014608739.1	CPBP family intramembrane glutamic endopeptidase	-
H0511_RS10235 (STHERMO_1964)	-	1703155..1703430 (-)	276	WP_011681681.1	hypothetical protein	-
H0511_RS08685	-	1703442..1703640 (-)	199	Protein_1681	helix-turn-helix transcriptional regulator	-
H0511_RS08690 (STHERMO_1966)	-	1703889..1705082 (-)	1194	WP_014608740.1	acetate kinase	-
H0511_RS08695 (STHERMO_1967)	comYH	1705138..1706094 (-)	957	WP_011226622.1	class I SAM-dependent methyltransferase	Machinery gene
H0511_RS08700 (STHERMO_1968)	comGG	1706139..1706456 (-)	318	WP_011681685.1	competence type IV pilus minor pilin ComGG	-
H0511_RS08705 (STHERMO_1969)	comYF	1706434..1706871 (-)	438	WP_179974042.1	competence type IV pilus minor pilin ComGF	Machinery gene
H0511_RS08710 (STHERMO_1970)	comGE	1706855..1707148 (-)	294	WP_179972344.1	competence type IV pilus minor pilin ComGE	-
H0511_RS08715 (STHERMO_1971)	comGD	1707120..1707548 (-)	429	WP_269473123.1	competence type IV pilus minor pilin ComGD	-
H0511_RS08720 (STHERMO_1972)	comYC	1707508..1707834 (-)	327	WP_179972346.1	competence type IV pilus major pilin ComGC	Machinery gene
H0511_RS08725 (STHERMO_1973)	comYB	1707831..1708931 (-)	1101	WP_179974043.1	competence type IV pilus assembly protein ComGB	Machinery gene
H0511_RS08730 (STHERMO_1974)	comGA/cglA/cilD	1708813..1709754 (-)	942	WP_179974044.1	competence type IV pilus ATPase ComGA	Machinery gene
H0511_RS08735 (STHERMO_1975)	-	1709835..1710197 (-)	363	WP_179972348.1	DUF1033 family protein	-

Sequence

Protein

• Length: 145 a.a.
• Molecular weight: 16361.77 Da
• Isoelectric Point: 7.7743

>NTDB_id=1130992 H0511_RS08705 WP_179974042.1 1706434..1706871(-) (comYF) [Streptococcus thermophilus isolate STH_CIRM_336]
MYLSSNLRAFTLLECLVALLVIAGSVQVYQGLTTVLVSNVKQVRQQENQDWLLFVQQMEAELEGCQLVKVEGNKLYVKQD
NQDLAFGLSSASDFRKTNADGRGYQPMLFDVKSSKVSQKNQIVTIQVTLKNELQRSFVYAFEKTG

Nucleotide

• Length: 438 bp

>NTDB_id=1130992 H0511_RS08705 WP_179974042.1 1706434..1706871(-) (comYF) [Streptococcus thermophilus isolate STH_CIRM_336]
ATGTATCTAAGCAGTAATCTGCGTGCCTTTACCCTCTTGGAATGTCTAGTGGCCTTGTTGGTCATTGCTGGCTCAGTTCA
AGTTTATCAAGGGTTAACCACTGTACTTGTGAGTAATGTTAAGCAGGTAAGACAACAAGAAAACCAAGACTGGCTTCTAT
TTGTTCAACAAATGGAGGCAGAATTAGAAGGATGTCAGTTGGTCAAGGTAGAGGGGAATAAACTCTATGTCAAGCAGGAT
AATCAAGACTTGGCTTTTGGTCTTTCAAGTGCCTCTGATTTTCGAAAAACAAATGCTGATGGTCGAGGTTATCAACCAAT
GCTTTTCGATGTCAAATCTAGTAAGGTAAGTCAAAAGAACCAGATAGTTACCATCCAAGTGACTCTTAAAAATGAACTAC
AAAGGAGTTTTGTTTATGCTTTTGAAAAAACAGGTTAG

Domains

Predicted by InterproScan.

• Putative Competence protein ComGF (ComGF) (39-134)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comYF	Streptococcus mutans UA140	57.447	97.241	0.559
comYF	Streptococcus mutans UA159	56.738	97.241	0.552
comGF/cglF	Streptococcus pneumoniae D39	48.571	96.552	0.469
comGF/cglF	Streptococcus pneumoniae Rx1	48.571	96.552	0.469
comGF/cglF	Streptococcus pneumoniae R6	48.571	96.552	0.469
comGF/cglF	Streptococcus pneumoniae TIGR4	48.571	96.552	0.469
comGF/cglF	Streptococcus mitis NCTC 12261	46.809	97.241	0.455
comGF/cglF	Streptococcus mitis SK321	46.099	97.241	0.448
comGF	Lactococcus lactis subsp. cremoris KW2	44.928	95.172	0.428