Detailed information    

insolico Bioinformatically predicted

Overview

Name   cinA   Type   Machinery gene
Locus tag   H0511_RS00460 Genome accession   NZ_LR822017
Coordinates   79594..80865 (+) Length   423 a.a.
NCBI ID   WP_179974149.1    Uniprot ID   A0A8D6XN90
Organism   Streptococcus thermophilus isolate STH_CIRM_336     
Function   facilitate localization of RecA (predicted from homology)   
Homologous recombination

Genomic Context

Location: 74594..85865
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  H0511_RS00430 (STHERMO_0081) - 74929..75367 (-) 439 Protein_65 LytTR family DNA-binding domain-containing protein -
  H0511_RS00435 (STHERMO_0082) - 75546..75848 (+) 303 WP_179974144.1 hypothetical protein -
  H0511_RS00440 (STHERMO_0083) mutL 75899..77842 (+) 1944 WP_179974145.1 DNA mismatch repair endonuclease MutL -
  H0511_RS00445 (STHERMO_0084) - 77972..78193 (+) 222 WP_179974146.1 hypothetical protein -
  H0511_RS00450 (STHERMO_0085) ruvA 78347..78937 (+) 591 WP_179974147.1 Holliday junction branch migration protein RuvA -
  H0511_RS00455 (STHERMO_0086) - 78944..79498 (+) 555 WP_179974148.1 DNA-3-methyladenine glycosylase I -
  H0511_RS00460 (STHERMO_0087) cinA 79594..80865 (+) 1272 WP_179974149.1 competence/damage-inducible protein A Machinery gene
  H0511_RS00465 (STHERMO_0088) recA 80901..82040 (+) 1140 WP_179972485.1 recombinase RecA Machinery gene
  H0511_RS00470 (STHERMO_0089) spx 82217..82615 (+) 399 WP_179972486.1 transcriptional regulator Spx -

Sequence

Protein


Download         Length: 423 a.a.        Molecular weight: 46051.46 Da        Isoelectric Point: 5.0955

>NTDB_id=1130942 H0511_RS00460 WP_179974149.1 79594..80865(+) (cinA) [Streptococcus thermophilus isolate STH_CIRM_336]
MKAELIAVGTEILTGQITNTNAQFLSEKLAELGIDVYFHTAVGDNENRLLSVLDQSSKRSDLVILCGGLGPTEDDLTKQT
LAKFLGKELIFDEEASKKLDSFFATRPKYTRTPNNERQAQIVEGAVPLQNLTGLAVGGIITVKGVTYVVLPGPPSELKPM
VNQELIPALTENHTTLYSRVLRFFGVGESQLVTIIKDLIINQTDPTIAPYARVGEVTLRLSTKASSQEEADRKLDVLEEQ
IRSTKTLDGKSLSDLIYGYGESNSLAYEVFYLLKKYGKTITAAESLTAGLFQASVADFPGASQVFKGGFVTYSMEEKAKM
LDIPLSKLEEHGVVSHFTAEKMAEGARVKTDSDYGIALTGVAGPDALEGHQAGTVFIGIADRNQVRSIKVVIGGRSRSDV
RYISTLYAFNLVRQALLQEDNSI

Nucleotide


Download         Length: 1272 bp        

>NTDB_id=1130942 H0511_RS00460 WP_179974149.1 79594..80865(+) (cinA) [Streptococcus thermophilus isolate STH_CIRM_336]
ATGAAAGCTGAATTGATTGCAGTAGGAACTGAAATTCTTACAGGGCAAATCACCAATACCAATGCCCAATTTTTATCTGA
AAAACTAGCTGAATTAGGAATTGACGTGTATTTTCACACAGCAGTAGGAGACAATGAAAACCGTCTACTTTCAGTCTTAG
ACCAGTCTAGTAAACGTAGCGATTTAGTCATACTCTGTGGAGGACTTGGCCCTACTGAGGATGACTTAACCAAACAAACA
TTAGCTAAGTTTTTAGGCAAAGAACTCATTTTTGATGAGGAGGCAAGTAAAAAACTGGATAGTTTTTTTGCTACTCGTCC
TAAATATACACGAACGCCTAATAATGAACGCCAAGCGCAAATTGTTGAGGGGGCTGTCCCCTTGCAAAATCTCACAGGTC
TGGCAGTTGGAGGAATTATTACTGTTAAAGGAGTGACCTATGTTGTCTTGCCTGGTCCGCCCAGTGAACTCAAACCTATG
GTGAACCAAGAGCTTATTCCAGCTCTTACAGAGAATCATACTACGCTTTATTCTAGAGTCCTAAGGTTTTTTGGTGTTGG
AGAAAGTCAATTGGTGACTATTATTAAAGATCTCATTATTAACCAAACGGACCCAACCATTGCGCCCTATGCTAGAGTGG
GAGAAGTGACCCTTCGCTTATCAACAAAGGCATCGTCGCAAGAAGAAGCGGATCGAAAACTAGATGTTTTAGAAGAACAA
ATTCGTTCTACTAAAACTCTAGATGGAAAAAGCTTGTCTGATCTCATCTATGGTTATGGAGAATCAAATAGTTTAGCTTA
TGAAGTGTTCTATTTGCTTAAGAAATATGGCAAAACTATTACTGCAGCTGAAAGTTTAACAGCTGGCTTATTTCAAGCTA
GTGTTGCTGATTTTCCTGGAGCTTCACAAGTATTCAAGGGTGGTTTTGTCACCTATAGCATGGAAGAAAAAGCTAAAATG
TTGGATATTCCCTTATCTAAATTAGAAGAGCATGGTGTTGTTAGTCATTTTACAGCAGAAAAAATGGCTGAGGGTGCCCG
AGTTAAGACAGATAGTGATTACGGAATTGCGCTTACTGGAGTAGCAGGACCAGATGCTTTGGAAGGGCATCAAGCAGGTA
CAGTCTTTATTGGTATTGCCGATAGAAACCAAGTGCGGTCAATTAAGGTTGTTATAGGTGGAAGAAGTCGATCTGATGTT
AGATATATCAGTACACTCTATGCCTTCAACCTAGTTCGCCAAGCTTTATTACAAGAGGACAACTCGATTTAA

Domains

Predicted by InterproScan.

Damage-inducible protein CinA KH domain (CinA_KH)

(178-243)

Probable molybdopterin binding domain (MoCF_biosynth)

(5-170)

Competence-damaged protein (CinA)

(264-415)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  cinA Streptococcus mitis SK321

74.94

99.054

0.742
  cinA Streptococcus mitis NCTC 12261

73.747

99.054

0.73
  cinA Streptococcus pneumoniae TIGR4

72.554

99.054

0.719
  cinA Streptococcus pneumoniae Rx1

72.315

99.054

0.716
  cinA Streptococcus pneumoniae R6

72.315

99.054

0.716
  cinA Streptococcus pneumoniae D39

72.076

99.054

0.714
  cinA Streptococcus mutans UA159

69.834

99.527

0.695
  cinA Streptococcus suis isolate S10

54.087

98.345

0.532
  cinA Bacillus subtilis subsp. subtilis str. 168

44.181

99.527

0.44

Multiple sequence alignment