Detailed information NTG1130735

Bioinformatically predicted

Overview

• Name: vicR
• Type: Regulator
• Locus tag: H0505_RS05230
• Genome accession: NZ_LR822012
• Coordinates: 1000336..1001043 (-)
• Length: 235 a.a.
• NCBI ID: WP_011681206.1
• Uniprot ID: -
• Organism: Streptococcus thermophilus isolate STH_CIRM_30
• Function: repress comCDE expression; repress comX expression (predicted from homology) Competence regulation

Genomic Context

Location: 995336..1006043

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
H0505_RS05205 (STHERMO_1138)	yidA	995687..996496 (+)	810	WP_011226081.1	sugar-phosphatase	-
H0505_RS05210 (STHERMO_1139)	-	996498..997712 (+)	1215	WP_011227270.1	aminoacyltransferase	-
H0505_RS05215	-	997764..998125 (-)	362	Protein_975	YbaN family protein	-
H0505_RS05220 (STHERMO_1140)	vicX	998185..998997 (-)	813	WP_179970872.1	MBL fold metallo-hydrolase	Regulator
H0505_RS05225 (STHERMO_1141)	vicK	999003..1000343 (-)	1341	WP_011226083.1	cell wall metabolism sensor histidine kinase VicK	Regulator
H0505_RS05230 (STHERMO_1142)	vicR	1000336..1001043 (-)	708	WP_011681206.1	response regulator YycF	Regulator
H0505_RS05235 (STHERMO_1144)	-	1001570..1002337 (+)	768	WP_179970873.1	amino acid ABC transporter ATP-binding protein	-
H0505_RS05240 (STHERMO_1145)	-	1002349..1003182 (+)	834	WP_179970874.1	transporter substrate-binding domain-containing protein	-
H0505_RS05245 (STHERMO_1146)	-	1003200..1003898 (+)	699	WP_065973256.1	amino acid ABC transporter permease	-
H0505_RS05250 (STHERMO_1147)	-	1003910..1004560 (+)	651	WP_011226088.1	amino acid ABC transporter permease	-
H0505_RS05255 (STHERMO_1148)	endA	1004631..1005512 (-)	882	WP_002953146.1	DNA/RNA non-specific endonuclease	Machinery gene
H0505_RS05260 (STHERMO_1149)	-	1005574..1005762 (-)	189	WP_011226090.1	DNA-directed RNA polymerase subunit beta	-

Sequence

Protein

• Length: 235 a.a.
• Molecular weight: 27058.98 Da
• Isoelectric Point: 5.0130

>NTDB_id=1130735 H0505_RS05230 WP_011681206.1 1000336..1001043(-) (vicR) [Streptococcus thermophilus isolate STH_CIRM_30]
MKKILVVDDERPISDIIKFNLTKEGYEVVTAFDGREALEQFEAKKPDLVILDLMLPELDGLEVAKEIRKTSHTPIIMLSA
KDSEFDKVIGLEIGADDYVTKPFSNRELLARIKAHLRRTETIETAVEESSNSGKQEISIGELVIVPDAFVAKKRGNEVEL
THREFELLFHLATHMGQVMTREHLLETVWGYDYFGDVRTVDVTIRRLREKIEDTPSRPEYILTRRGVGYYMKNYD

Nucleotide

• Length: 708 bp

>NTDB_id=1130735 H0505_RS05230 WP_011681206.1 1000336..1001043(-) (vicR) [Streptococcus thermophilus isolate STH_CIRM_30]
ATGAAAAAAATTCTAGTTGTTGATGATGAAAGACCAATCTCCGATATCATCAAGTTTAACCTTACTAAGGAGGGTTATGA
AGTGGTTACGGCCTTTGATGGGCGAGAAGCTTTGGAACAATTTGAAGCTAAAAAACCAGACTTGGTTATTCTGGACTTGA
TGTTGCCTGAACTGGATGGTTTGGAAGTTGCCAAGGAAATCCGTAAAACGAGCCACACACCGATTATCATGCTTTCAGCT
AAAGATAGTGAGTTTGATAAGGTTATCGGATTAGAAATTGGGGCAGACGACTATGTGACTAAGCCATTTTCTAACCGTGA
ATTGTTGGCACGTATTAAAGCCCACTTGCGTCGTACAGAAACGATTGAAACTGCAGTAGAAGAGAGCTCTAACTCTGGCA
AACAAGAAATTTCAATTGGTGAGTTGGTTATTGTTCCGGATGCCTTTGTTGCTAAAAAACGTGGAAACGAAGTTGAGTTG
ACCCACCGTGAATTTGAGTTACTCTTCCATTTGGCAACTCATATGGGACAAGTTATGACGCGAGAACATTTGCTTGAAAC
CGTTTGGGGCTATGACTATTTTGGGGATGTTCGTACTGTGGACGTAACGATTCGTCGTCTGCGTGAAAAAATTGAAGATA
CACCTAGCCGTCCTGAATATATCTTGACGCGTCGTGGTGTCGGTTATTACATGAAGAATTATGACTAG

Domains

Predicted by InterproScan.

• Response regulator receiver domain (Response_reg) (4-113)

• Transcriptional regulatory protein, C terminal (Trans_reg_C) (155-230)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vicR	Streptococcus mutans UA159	85.532	100	0.855
micA	Streptococcus pneumoniae Cp1015	80.258	99.149	0.796
covR	Lactococcus lactis subsp. lactis strain DGCC12653	46.32	98.298	0.455
covR	Streptococcus salivarius strain HSISS4	45.299	99.574	0.451
scnR	Streptococcus mutans UA159	38.559	100	0.387