Detailed information    

insolico Bioinformatically predicted

Overview

Name   vicK   Type   Regulator
Locus tag   H0505_RS05225 Genome accession   NZ_LR822012
Coordinates   999003..1000343 (-) Length   446 a.a.
NCBI ID   WP_011226083.1    Uniprot ID   A0A060BIR3
Organism   Streptococcus thermophilus isolate STH_CIRM_30     
Function   repress comCDE expression; repress comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 994003..1005343
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  H0505_RS05195 (STHERMO_1135) - 994122..994508 (-) 387 WP_002953113.1 DUF1934 domain-containing protein -
  H0505_RS05200 - 994600..995479 (-) 880 Protein_972 GNAT family N-acetyltransferase -
  H0505_RS05205 (STHERMO_1138) yidA 995687..996496 (+) 810 WP_011226081.1 sugar-phosphatase -
  H0505_RS05210 (STHERMO_1139) - 996498..997712 (+) 1215 WP_011227270.1 aminoacyltransferase -
  H0505_RS05215 - 997764..998125 (-) 362 Protein_975 YbaN family protein -
  H0505_RS05220 (STHERMO_1140) vicX 998185..998997 (-) 813 WP_179970872.1 MBL fold metallo-hydrolase Regulator
  H0505_RS05225 (STHERMO_1141) vicK 999003..1000343 (-) 1341 WP_011226083.1 cell wall metabolism sensor histidine kinase VicK Regulator
  H0505_RS05230 (STHERMO_1142) vicR 1000336..1001043 (-) 708 WP_011681206.1 response regulator YycF Regulator
  H0505_RS05235 (STHERMO_1144) - 1001570..1002337 (+) 768 WP_179970873.1 amino acid ABC transporter ATP-binding protein -
  H0505_RS05240 (STHERMO_1145) - 1002349..1003182 (+) 834 WP_179970874.1 transporter substrate-binding domain-containing protein -
  H0505_RS05245 (STHERMO_1146) - 1003200..1003898 (+) 699 WP_065973256.1 amino acid ABC transporter permease -
  H0505_RS05250 (STHERMO_1147) - 1003910..1004560 (+) 651 WP_011226088.1 amino acid ABC transporter permease -

Sequence

Protein


Download         Length: 446 a.a.        Molecular weight: 50782.15 Da        Isoelectric Point: 5.2464

>NTDB_id=1130734 H0505_RS05225 WP_011226083.1 999003..1000343(-) (vicK) [Streptococcus thermophilus isolate STH_CIRM_30]
MTSIGLNITSFELALLFMLLFVAFYFIFLAYRDYQQVKNIRKLTKRVKSLMAGNYNEKLCIKGDSELLELANSLNDLSDV
FRLTHENLIQEKNRLSSVLSYMSDGVIATNRLGQITMINSTAQRLLNLDRETATQMSILDILDGENPYTYSELLSKTPEI
HLSRRDANDEFVTLRVNFALIRKESGFISGLVAVLHDATEQEKEERERRLFVSNVSHELRTPLTSVKSYLEALDDGALNE
EIAPNFIKVSLDETNRMMRMITDLLALSRIDNKSTQLNVEMTNFTAFMTYILNRFGQIKSQETNPGKSYEIIRDYPVNSI
WVEIDTDKMTQVIDNILNNAIKYSPDGGKITVSMKTTDTQLIVSISDQGLGIPKKDLPLIFDRFYRVDKARSRAQGGTGL
GLSIAKEIVKQHNGFIWAKSEYGKGSTFTIVLPYDQDAMMVDEWEM

Nucleotide


Download         Length: 1341 bp        

>NTDB_id=1130734 H0505_RS05225 WP_011226083.1 999003..1000343(-) (vicK) [Streptococcus thermophilus isolate STH_CIRM_30]
ATGACTAGTATTGGCTTAAATATTACAAGCTTTGAACTGGCCTTACTCTTTATGCTCCTCTTTGTTGCTTTCTATTTCAT
TTTTCTAGCTTATCGTGATTATCAACAGGTCAAAAATATCCGAAAGTTGACTAAGAGAGTCAAATCCCTTATGGCAGGTA
ATTATAATGAAAAATTATGCATAAAGGGAGATTCAGAGCTTTTAGAGCTAGCTAATAGCTTGAATGATTTGTCGGACGTC
TTTCGTTTGACACATGAAAATCTAATCCAGGAAAAAAACCGCTTATCATCTGTCCTTTCGTACATGAGTGACGGGGTTAT
TGCGACCAATCGCCTTGGTCAGATTACTATGATTAATAGTACTGCCCAACGCTTGTTGAATTTAGATCGCGAAACTGCGA
CTCAGATGTCTATTTTGGATATATTAGATGGTGAGAATCCCTATACCTATAGTGAATTGTTGTCTAAGACACCCGAAATC
CATCTGTCGCGTCGAGATGCTAACGATGAATTTGTGACGCTACGTGTTAATTTTGCATTAATTCGTAAGGAATCTGGTTT
TATTTCAGGTCTGGTAGCCGTTCTTCATGATGCCACTGAGCAGGAAAAAGAAGAGCGCGAACGCCGTCTCTTCGTATCAA
ATGTTAGTCACGAATTGCGGACGCCTTTAACTTCTGTGAAATCCTATCTTGAAGCGCTTGATGATGGTGCTCTCAACGAA
GAGATTGCTCCAAACTTTATCAAAGTTTCTTTAGATGAAACCAACCGCATGATGCGTATGATTACTGACCTCTTGGCATT
ATCTCGAATTGACAATAAAAGCACACAGCTTAATGTTGAAATGACAAACTTTACAGCCTTTATGACCTATATCTTGAATC
GGTTTGGTCAAATTAAGAGTCAAGAAACTAATCCAGGTAAGTCTTATGAAATCATTCGAGATTACCCAGTAAACTCTATT
TGGGTGGAAATTGATACTGATAAGATGACCCAGGTCATAGATAATATACTTAATAATGCCATCAAGTATTCTCCTGATGG
TGGGAAAATTACAGTATCTATGAAAACGACAGACACTCAGTTGATTGTTTCTATTTCTGACCAAGGTTTAGGAATTCCTA
AAAAAGATTTACCTCTGATTTTTGACCGTTTTTACCGTGTTGATAAGGCCAGAAGTCGTGCTCAGGGTGGAACAGGACTT
GGCTTATCCATTGCAAAAGAAATTGTTAAACAACATAATGGCTTCATTTGGGCTAAGAGTGAGTATGGTAAGGGATCAAC
TTTTACAATTGTGCTTCCATATGACCAGGACGCAATGATGGTCGATGAATGGGAGATGTAG

Domains

Predicted by InterproScan.

His Kinase A (phospho-acceptor) domain (HisKA)

(208-272)

HAMP domain (HAMP)

(37-79)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(325-435)

PAS fold (PAS)

(94-197)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A060BIR3

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vicK Streptococcus mutans UA159

74.638

92.825

0.693
  micB Streptococcus pneumoniae Cp1015

66.282

97.085

0.644

Multiple sequence alignment