Detailed information NTG1130736

Bioinformatically predicted

Overview

• Name: endA
• Type: Machinery gene
• Locus tag: H0505_RS05255
• Genome accession: NZ_LR822012
• Coordinates: 1004631..1005512 (-)
• Length: 293 a.a.
• NCBI ID: WP_002953146.1
• Uniprot ID: -
• Organism: Streptococcus thermophilus isolate STH_CIRM_30
• Function: cleavage of dsDNA into ssDNA (predicted from homology) DNA processing

Genomic Context

Location: 999631..1010512

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
H0505_RS05230 (STHERMO_1142)	vicR	1000336..1001043 (-)	708	WP_011681206.1	response regulator YycF	Regulator
H0505_RS05235 (STHERMO_1144)	-	1001570..1002337 (+)	768	WP_179970873.1	amino acid ABC transporter ATP-binding protein	-
H0505_RS05240 (STHERMO_1145)	-	1002349..1003182 (+)	834	WP_179970874.1	transporter substrate-binding domain-containing protein	-
H0505_RS05245 (STHERMO_1146)	-	1003200..1003898 (+)	699	WP_065973256.1	amino acid ABC transporter permease	-
H0505_RS05250 (STHERMO_1147)	-	1003910..1004560 (+)	651	WP_011226088.1	amino acid ABC transporter permease	-
H0505_RS05255 (STHERMO_1148)	endA	1004631..1005512 (-)	882	WP_002953146.1	DNA/RNA non-specific endonuclease	Machinery gene
H0505_RS05260 (STHERMO_1149)	-	1005574..1005762 (-)	189	WP_011226090.1	DNA-directed RNA polymerase subunit beta	-
H0505_RS05265 (STHERMO_1150)	murA	1005764..1007035 (-)	1272	WP_164178134.1	UDP-N-acetylglucosamine 1-carboxyvinyltransferase	-
H0505_RS05270 (STHERMO_1151)	-	1007105..1007341 (-)	237	WP_002946959.1	DUF1146 family protein	-
H0505_RS05275 (STHERMO_1152)	galE	1007529..1008542 (-)	1014	WP_179970875.1	UDP-glucose 4-epimerase GalE	-
H0505_RS05280 (STHERMO_1153)	-	1008557..1009012 (-)	456	WP_179970876.1	DUF4832 domain-containing protein	-

Sequence

Protein

• Length: 293 a.a.
• Molecular weight: 31773.54 Da
• Isoelectric Point: 10.2316

>NTDB_id=1130736 H0505_RS05255 WP_002953146.1 1004631..1005512(-) (endA) [Streptococcus thermophilus isolate STH_CIRM_30]
MAKRKTSLTNKQKRQLVTLIIAALIAVLGYLGTSNKLSPDNPIRKVASLVSGKSNKSIKSNGSTNSQSTPQEQLAETVMT
SSVKSQLGNSLEWNGAGAYIINRNKTNLNAKVSSQPYANNQVKTVQGQTVPTVANALLSKATRQYKNRQETGNGSTSWTP
AGWHQVQNLSGEYSHAVDRGHLLGYALIGGLKGFDASTSNPENIAVQTAWANQAYSDSSTGQNYYESLVRKALDKNKRVR
YRVTLIYEGENLIPSGTHLEAKSADGSLEFNVFVPNVQEGITLDYYSGKVTVN

Nucleotide

• Length: 882 bp

>NTDB_id=1130736 H0505_RS05255 WP_002953146.1 1004631..1005512(-) (endA) [Streptococcus thermophilus isolate STH_CIRM_30]
ATGGCAAAAAGAAAGACATCTTTGACAAATAAACAGAAACGTCAGTTAGTCACATTAATAATAGCAGCTTTGATAGCTGT
TTTAGGTTACCTAGGAACCAGTAACAAGCTCTCGCCTGATAATCCTATCAGAAAAGTAGCAAGCCTAGTTTCAGGGAAAT
CTAACAAATCCATTAAATCTAATGGTTCAACAAATAGTCAGTCTACACCACAAGAGCAGCTTGCTGAGACAGTAATGACT
AGTTCAGTCAAAAGCCAACTGGGTAATTCCTTGGAATGGAATGGAGCTGGGGCCTACATTATTAATAGAAATAAGACGAA
TCTAAATGCTAAGGTATCAAGCCAACCCTATGCTAATAACCAAGTCAAAACGGTTCAAGGACAAACTGTTCCTACAGTTG
CTAATGCCTTATTAAGTAAAGCAACTAGACAGTACAAAAATCGTCAAGAAACAGGGAATGGTTCAACCTCTTGGACACCA
GCTGGATGGCACCAGGTTCAAAATTTATCAGGAGAGTATAGCCATGCCGTAGATAGAGGCCATTTGCTAGGTTATGCACT
GATAGGTGGTTTGAAAGGATTTGATGCCTCGACTTCAAATCCAGAGAATATTGCTGTTCAAACTGCTTGGGCAAATCAAG
CATATAGCGATAGTTCTACAGGCCAAAACTATTATGAAAGCCTAGTACGAAAAGCTCTGGATAAAAACAAACGTGTTCGT
TATCGTGTGACCCTGATTTATGAAGGAGAGAATCTCATTCCATCAGGAACACATCTTGAAGCTAAGTCAGCAGACGGCTC
ACTTGAGTTTAATGTCTTTGTTCCAAATGTACAAGAGGGAATTACACTAGATTACTATTCAGGAAAAGTAACGGTGAATT
GA

Domains

Predicted by InterproScan.

• DNA/RNA non-specific endonuclease (Endonuclease_NS) (101-266)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
endA	Streptococcus pneumoniae Rx1	72.803	81.57	0.594
endA	Streptococcus pneumoniae D39	72.803	81.57	0.594
endA	Streptococcus pneumoniae R6	72.803	81.57	0.594
endA	Streptococcus pneumoniae TIGR4	72.803	81.57	0.594