Detailed information    

insolico Bioinformatically predicted

Overview

Name   cinA   Type   Machinery gene
Locus tag   H0505_RS00360 Genome accession   NZ_LR822012
Coordinates   62785..64056 (+) Length   423 a.a.
NCBI ID   WP_084829277.1    Uniprot ID   -
Organism   Streptococcus thermophilus isolate STH_CIRM_30     
Function   facilitate localization of RecA (predicted from homology)   
Homologous recombination

Genomic Context

Location: 57785..69056
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  H0505_RS00330 (STHERMO_0060) - 58120..58511 (-) 392 Protein_45 LytTR family DNA-binding domain-containing protein -
  H0505_RS00335 (STHERMO_0061) - 58735..59040 (+) 306 WP_014621013.1 hypothetical protein -
  H0505_RS00340 (STHERMO_0062) mutL 59092..61035 (+) 1944 WP_011225282.1 DNA mismatch repair endonuclease MutL -
  H0505_RS00345 (STHERMO_0063) - 61165..61386 (+) 222 WP_002949052.1 hypothetical protein -
  H0505_RS00350 (STHERMO_0064) ruvA 61538..62128 (+) 591 WP_084829275.1 Holliday junction branch migration protein RuvA -
  H0505_RS00355 (STHERMO_0065) - 62135..62689 (+) 555 WP_011225284.1 DNA-3-methyladenine glycosylase I -
  H0505_RS00360 (STHERMO_0066) cinA 62785..64056 (+) 1272 WP_084829277.1 competence/damage-inducible protein A Machinery gene
  H0505_RS00365 (STHERMO_0067) recA 64092..65231 (+) 1140 WP_011680606.1 recombinase RecA Machinery gene
  H0505_RS00370 (STHERMO_0068) spx 65408..65806 (+) 399 WP_002949058.1 transcriptional regulator Spx -

Sequence

Protein


Download         Length: 423 a.a.        Molecular weight: 45983.39 Da        Isoelectric Point: 5.2081

>NTDB_id=1130705 H0505_RS00360 WP_084829277.1 62785..64056(+) (cinA) [Streptococcus thermophilus isolate STH_CIRM_30]
MKAELIAVGTEILTGQITNTNAQFLSEKLAELGIDVYFHTAVGDNENRLLSVLDQSSKRSDLVILCGGLGPTEDDLTKQT
LAKFLGKELIFDEEASKKLDSFFATRPKHTRTPNNERQAQIVEGAVPLQNLTGLAVGGIITVEGVTYVVLPGPPSELKPM
VNQELIPALTENHTTLYSRVLRFFGVGESQLVTIIKDLIVNQTDPTIAPYAKVGEVTLRLSTKASSQEEADRKLDVLEEQ
IRSTKTLDGKSLSDLIYGYGESNSLAYEVFYLLKKYGKTITAAESLTAGLFQASVADFPGASQVFKGGFVTYSMKEKAKM
LDIPLSKLEEHGVVSHFTAEKMAEGARVKTDSDYGIALTGVAGPDALEGHQAGTVFIGIADRNQVRSIKVVIGGRSRSDV
RYISTLYAFNLVRQALLQEDNSI

Nucleotide


Download         Length: 1272 bp        

>NTDB_id=1130705 H0505_RS00360 WP_084829277.1 62785..64056(+) (cinA) [Streptococcus thermophilus isolate STH_CIRM_30]
ATGAAAGCTGAATTGATTGCAGTAGGAACTGAAATTCTTACAGGGCAAATCACCAATACCAATGCCCAATTTTTATCTGA
AAAACTAGCTGAATTAGGAATTGACGTGTATTTTCACACAGCGGTAGGAGACAATGAAAACCGTCTACTTTCAGTCTTAG
ACCAGTCTAGTAAACGTAGCGATTTAGTCATACTCTGTGGAGGACTTGGCCCTACTGAGGATGACTTAACCAAACAAACA
TTGGCTAAGTTTTTAGGCAAAGAACTCATTTTTGATGAGGAGGCAAGTAAAAAACTGGATAGTTTCTTTGCTACTCGTCC
TAAACATACACGAACGCCTAATAATGAACGCCAAGCGCAAATTGTTGAGGGGGCTGTCCCCTTGCAAAATCTCACAGGCC
TGGCAGTTGGAGGAATTATTACTGTTGAAGGAGTGACCTATGTTGTCTTGCCTGGTCCTCCAAGTGAACTCAAACCTATG
GTGAACCAAGAGCTTATTCCAGCTCTTACAGAGAATCATACTACGCTTTATTCTAGAGTCCTAAGGTTTTTTGGTGTTGG
AGAAAGTCAATTGGTGACTATTATTAAAGATCTCATTGTTAACCAAACAGACCCAACCATTGCGCCCTATGCTAAAGTGG
GAGAAGTGACCCTTCGCTTATCAACAAAGGCATCGTCGCAAGAAGAAGCGGATCGAAAACTAGATGTTTTAGAAGAACAA
ATTCGTTCTACTAAAACTCTAGATGGAAAAAGCTTGTCTGATCTCATCTATGGATATGGAGAATCAAATAGCTTAGCTTA
TGAAGTGTTCTATTTGCTTAAGAAATATGGCAAAACTATTACTGCAGCTGAAAGTTTAACAGCTGGCTTATTTCAAGCTA
GTGTTGCTGATTTTCCTGGAGCTTCACAAGTATTCAAGGGTGGTTTTGTCACCTATAGCATGAAAGAAAAAGCTAAAATG
TTGGATATTCCCTTATCTAAATTAGAAGAGCATGGTGTTGTTAGTCATTTTACAGCAGAAAAAATGGCTGAGGGTGCCCG
AGTTAAGACAGATAGTGATTACGGAATTGCGCTTACTGGAGTAGCAGGACCAGATGCTTTGGAAGGGCATCAAGCAGGTA
CAGTCTTTATTGGTATTGCCGATAGAAACCAAGTGCGGTCAATTAAGGTTGTTATAGGTGGAAGAAGTCGATCTGATGTT
AGATATATCAGTACACTCTATGCCTTTAACCTAGTTCGCCAAGCTTTATTACAAGAGGACAACTCAATTTAA

Domains

Predicted by InterproScan.

Probable molybdopterin binding domain (MoCF_biosynth)

(5-170)

Competence-damaged protein (CinA)

(264-415)

Damage-inducible protein CinA KH domain (CinA_KH)

(178-243)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  cinA Streptococcus mitis SK321

74.702

99.054

0.74
  cinA Streptococcus mitis NCTC 12261

73.508

99.054

0.728
  cinA Streptococcus pneumoniae TIGR4

72.315

99.054

0.716
  cinA Streptococcus pneumoniae Rx1

72.076

99.054

0.714
  cinA Streptococcus pneumoniae R6

72.076

99.054

0.714
  cinA Streptococcus pneumoniae D39

71.838

99.054

0.712
  cinA Streptococcus mutans UA159

69.834

99.527

0.695
  cinA Streptococcus suis isolate S10

54.327

98.345

0.534
  cinA Bacillus subtilis subsp. subtilis str. 168

44.418

99.527

0.442

Multiple sequence alignment