Detailed information NTG1130447

Bioinformatically predicted

Overview

• Name: vicR
• Type: Regulator
• Locus tag: STHERMO_RS05490
• Genome accession: NZ_LR822006
• Coordinates: 1037515..1038222 (-)
• Length: 235 a.a.
• NCBI ID: WP_011227274.1
• Uniprot ID: -
• Organism: Streptococcus thermophilus isolate STH_CIRM_16
• Function: repress comCDE expression; repress comX expression (predicted from homology) Competence regulation

Genomic Context

Location: 1032515..1043222

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
STHERMO_RS05465 (STHERMO_1206)	yidA	1032866..1033675 (+)	810	WP_011226081.1	sugar-phosphatase	-
STHERMO_RS05470 (STHERMO_1207)	-	1033677..1034891 (+)	1215	WP_011227270.1	aminoacyltransferase	-
STHERMO_RS05475	-	1034943..1035304 (-)	362	Protein_1013	YbaN family protein	-
STHERMO_RS05480 (STHERMO_1208)	vicX	1035364..1036176 (-)	813	WP_011681204.1	MBL fold metallo-hydrolase	Regulator
STHERMO_RS05485 (STHERMO_1209)	vicK	1036182..1037522 (-)	1341	WP_011227273.1	cell wall metabolism sensor histidine kinase VicK	Regulator
STHERMO_RS05490 (STHERMO_1210)	vicR	1037515..1038222 (-)	708	WP_011227274.1	response regulator YycF	Regulator
STHERMO_RS05495 (STHERMO_1212)	-	1038754..1039521 (+)	768	WP_011227275.1	amino acid ABC transporter ATP-binding protein	-
STHERMO_RS05500 (STHERMO_1213)	-	1039533..1040366 (+)	834	WP_011227276.1	transporter substrate-binding domain-containing protein	-
STHERMO_RS05505 (STHERMO_1214)	-	1040384..1041082 (+)	699	WP_179970492.1	amino acid ABC transporter permease	-
STHERMO_RS05510 (STHERMO_1215)	-	1041094..1041744 (+)	651	WP_011226088.1	amino acid ABC transporter permease	-
STHERMO_RS05515 (STHERMO_1216)	endA	1041815..1042696 (-)	882	WP_011681210.1	DNA/RNA non-specific endonuclease	Machinery gene
STHERMO_RS05520 (STHERMO_1217)	-	1042758..1042946 (-)	189	WP_179970493.1	DNA-directed RNA polymerase subunit beta	-

Sequence

Protein

• Length: 235 a.a.
• Molecular weight: 27115.09 Da
• Isoelectric Point: 5.0130

>NTDB_id=1130447 STHERMO_RS05490 WP_011227274.1 1037515..1038222(-) (vicR) [Streptococcus thermophilus isolate STH_CIRM_16]
MKKILVVDDERPISDIIKFNLTKEGYEVVTAFDGREALEQFEAKKPDLVILDLMLPELDGLEIVKEIRKTSHTPIIMLSA
KDSEFDKVIGLEIGADDYVTKPFSNRELLARIKAHLRRTETIETAVEESSNSGKQEISIGELIIVPDAFVAKKRGNEVEL
THREFELLFHLATHMGQVMTREHLLETVWGYDYFGDVRTVDVTIRRLREKIEDTPSRPEYILTRRGVGYYMKNYD

Nucleotide

• Length: 708 bp

>NTDB_id=1130447 STHERMO_RS05490 WP_011227274.1 1037515..1038222(-) (vicR) [Streptococcus thermophilus isolate STH_CIRM_16]
ATGAAAAAAATTCTAGTTGTTGATGATGAAAGACCAATCTCCGATATCATCAAGTTTAACCTTACTAAGGAGGGTTATGA
AGTGGTTACGGCCTTTGATGGGCGAGAAGCTTTGGAACAATTTGAAGCTAAAAAACCAGACTTGGTTATTCTGGACTTGA
TGTTGCCTGAACTGGATGGTTTGGAAATTGTCAAGGAAATCCGTAAAACGAGCCACACACCGATTATCATGCTTTCAGCT
AAAGATAGTGAGTTTGATAAGGTTATCGGATTAGAAATTGGGGCAGACGACTATGTGACTAAGCCATTTTCTAACCGTGA
ATTGTTGGCACGTATTAAAGCCCACTTGCGTCGTACAGAAACGATTGAAACTGCAGTAGAAGAGAGCTCTAACTCTGGCA
AACAAGAAATTTCAATTGGTGAGTTGATTATTGTTCCGGATGCCTTTGTTGCTAAAAAACGTGGAAACGAAGTTGAGTTG
ACCCACCGTGAATTTGAGTTACTCTTCCATTTGGCAACTCATATGGGACAAGTTATGACGCGTGAACATTTGCTTGAAAC
CGTTTGGGGCTATGACTATTTTGGGGATGTTCGTACTGTGGACGTAACGATTCGTCGTCTGCGTGAAAAAATTGAAGATA
CACCTAGCCGTCCTGAATATATCTTGACGCGTCGTGGTGTCGGTTATTACATGAAGAATTATGACTAG

Domains

Predicted by InterproScan.

• Response regulator receiver domain (Response_reg) (4-113)

• Transcriptional regulatory protein, C terminal (Trans_reg_C) (155-230)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vicR	Streptococcus mutans UA159	84.681	100	0.847
micA	Streptococcus pneumoniae Cp1015	79.399	99.149	0.787
covR	Streptococcus salivarius strain HSISS4	44.872	99.574	0.447
covR	Lactococcus lactis subsp. lactis strain DGCC12653	45.022	98.298	0.443
scnR	Streptococcus mutans UA159	38.136	100	0.383