Detailed information NTG1130448

Bioinformatically predicted

Overview

• Name: endA
• Type: Machinery gene
• Locus tag: STHERMO_RS05515
• Genome accession: NZ_LR822006
• Coordinates: 1041815..1042696 (-)
• Length: 293 a.a.
• NCBI ID: WP_011681210.1
• Uniprot ID: -
• Organism: Streptococcus thermophilus isolate STH_CIRM_16
• Function: cleavage of dsDNA into ssDNA (predicted from homology) DNA processing

Genomic Context

Location: 1036815..1047696

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
STHERMO_RS05490 (STHERMO_1210)	vicR	1037515..1038222 (-)	708	WP_011227274.1	response regulator YycF	Regulator
STHERMO_RS05495 (STHERMO_1212)	-	1038754..1039521 (+)	768	WP_011227275.1	amino acid ABC transporter ATP-binding protein	-
STHERMO_RS05500 (STHERMO_1213)	-	1039533..1040366 (+)	834	WP_011227276.1	transporter substrate-binding domain-containing protein	-
STHERMO_RS05505 (STHERMO_1214)	-	1040384..1041082 (+)	699	WP_179970492.1	amino acid ABC transporter permease	-
STHERMO_RS05510 (STHERMO_1215)	-	1041094..1041744 (+)	651	WP_011226088.1	amino acid ABC transporter permease	-
STHERMO_RS05515 (STHERMO_1216)	endA	1041815..1042696 (-)	882	WP_011681210.1	DNA/RNA non-specific endonuclease	Machinery gene
STHERMO_RS05520 (STHERMO_1217)	-	1042758..1042946 (-)	189	WP_179970493.1	DNA-directed RNA polymerase subunit beta	-
STHERMO_RS05525 (STHERMO_1218)	murA	1042948..1044219 (-)	1272	WP_179970494.1	UDP-N-acetylglucosamine 1-carboxyvinyltransferase	-
STHERMO_RS05530 (STHERMO_1219)	-	1044288..1044524 (-)	237	WP_002946959.1	DUF1146 family protein	-
STHERMO_RS05535 (STHERMO_1220)	galE	1044713..1045726 (-)	1014	WP_002946961.1	UDP-glucose 4-epimerase GalE	-
STHERMO_RS05540 (STHERMO_1221)	-	1045741..1046175 (-)	435	WP_232085796.1	DUF4832 domain-containing protein	-

Sequence

Protein

• Length: 293 a.a.
• Molecular weight: 31773.50 Da
• Isoelectric Point: 10.1789

>NTDB_id=1130448 STHERMO_RS05515 WP_011681210.1 1041815..1042696(-) (endA) [Streptococcus thermophilus isolate STH_CIRM_16]
MAKRKTSLTNKQKRQLVTLIIAALIAVLGYLGTSNKLSPDNPIRQVASLVSGKSNKSIKSNGSTNSQSTPQEQLAETVMT
SSVKSQLGNSLEWNGAGAYIINRNKTNLNAKVSSQPYANNQVKTVQGQTVPTVANALLSKATRQYKNRQETGNGSTSWTP
AGWHQVQNLSGEYSHAVDRGHLLGYALIGGLKGFDASTSNPENIAVQTAWANQAYSDSSTGQNYYESLVRKALDKNKRVR
YRVTLIYEGENLIPSGTHLEAKSADGSLEFNVFVPNVQEGITLDYYSGKVTVN

Nucleotide

• Length: 882 bp

>NTDB_id=1130448 STHERMO_RS05515 WP_011681210.1 1041815..1042696(-) (endA) [Streptococcus thermophilus isolate STH_CIRM_16]
ATGGCAAAAAGAAAGACATCTTTGACAAATAAACAGAAACGTCAGTTAGTCACATTAATAATAGCAGCTTTGATAGCTGT
TTTAGGTTACCTAGGAACCAGTAACAAGCTCTCGCCTGATAATCCTATCAGACAAGTAGCAAGCCTAGTTTCAGGGAAAT
CTAACAAATCCATTAAATCTAATGGTTCAACAAATAGTCAGTCTACACCACAAGAGCAGCTTGCTGAGACAGTAATGACT
AGTTCAGTCAAAAGCCAACTGGGTAATTCCTTGGAATGGAATGGAGCTGGGGCCTACATTATTAATAGAAATAAGACGAA
TCTAAATGCTAAGGTATCAAGCCAACCTTATGCTAATAACCAAGTTAAAACGGTTCAAGGACAAACTGTTCCTACAGTTG
CCAATGCCTTATTAAGTAAAGCAACTAGACAGTACAAAAATCGTCAAGAAACAGGGAATGGTTCAACCTCTTGGACACCA
GCTGGATGGCACCAGGTTCAAAATTTATCAGGAGAGTATAGCCATGCCGTAGATAGAGGCCATTTGCTAGGTTATGCACT
GATAGGTGGTTTGAAAGGATTTGATGCCTCGACTTCAAATCCAGAGAATATTGCTGTTCAAACTGCTTGGGCAAATCAAG
CATATAGCGATAGTTCTACAGGCCAAAACTATTATGAAAGCCTAGTACGAAAAGCCCTGGATAAAAACAAACGTGTTCGT
TATCGTGTGACCCTGATTTATGAAGGAGAGAATCTCATTCCATCAGGAACACATCTTGAAGCTAAGTCAGCAGACGGCTC
ACTTGAGTTTAATGTCTTTGTTCCAAATGTACAAGAGGGAATTACACTAGATTACTATTCAGGAAAAGTAACGGTGAATT
GA

Domains

Predicted by InterproScan.

• DNA/RNA non-specific endonuclease (Endonuclease_NS) (101-266)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
endA	Streptococcus pneumoniae Rx1	72.803	81.57	0.594
endA	Streptococcus pneumoniae D39	72.803	81.57	0.594
endA	Streptococcus pneumoniae R6	72.803	81.57	0.594
endA	Streptococcus pneumoniae TIGR4	72.803	81.57	0.594