Detailed information    

insolico Bioinformatically predicted

Overview

Name   vicK   Type   Regulator
Locus tag   STHERMO_RS05485 Genome accession   NZ_LR822006
Coordinates   1036182..1037522 (-) Length   446 a.a.
NCBI ID   WP_011227273.1    Uniprot ID   -
Organism   Streptococcus thermophilus isolate STH_CIRM_16     
Function   repress comCDE expression; repress comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1031182..1042522
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  STHERMO_RS05455 (STHERMO_1202) - 1031301..1031687 (-) 387 WP_002953113.1 DUF1934 domain-containing protein -
  STHERMO_RS05460 - 1031779..1032658 (-) 880 Protein_1010 GNAT family N-acetyltransferase -
  STHERMO_RS05465 (STHERMO_1206) yidA 1032866..1033675 (+) 810 WP_011226081.1 sugar-phosphatase -
  STHERMO_RS05470 (STHERMO_1207) - 1033677..1034891 (+) 1215 WP_011227270.1 aminoacyltransferase -
  STHERMO_RS05475 - 1034943..1035304 (-) 362 Protein_1013 YbaN family protein -
  STHERMO_RS05480 (STHERMO_1208) vicX 1035364..1036176 (-) 813 WP_011681204.1 MBL fold metallo-hydrolase Regulator
  STHERMO_RS05485 (STHERMO_1209) vicK 1036182..1037522 (-) 1341 WP_011227273.1 cell wall metabolism sensor histidine kinase VicK Regulator
  STHERMO_RS05490 (STHERMO_1210) vicR 1037515..1038222 (-) 708 WP_011227274.1 response regulator YycF Regulator
  STHERMO_RS05495 (STHERMO_1212) - 1038754..1039521 (+) 768 WP_011227275.1 amino acid ABC transporter ATP-binding protein -
  STHERMO_RS05500 (STHERMO_1213) - 1039533..1040366 (+) 834 WP_011227276.1 transporter substrate-binding domain-containing protein -
  STHERMO_RS05505 (STHERMO_1214) - 1040384..1041082 (+) 699 WP_179970492.1 amino acid ABC transporter permease -
  STHERMO_RS05510 (STHERMO_1215) - 1041094..1041744 (+) 651 WP_011226088.1 amino acid ABC transporter permease -

Sequence

Protein


Download         Length: 446 a.a.        Molecular weight: 50768.12 Da        Isoelectric Point: 5.2464

>NTDB_id=1130446 STHERMO_RS05485 WP_011227273.1 1036182..1037522(-) (vicK) [Streptococcus thermophilus isolate STH_CIRM_16]
MTSIGLNITSFELALLFMLLFVAFYFIFLAYRDYQQVKNIRKLTKRVKSLMAGNYNEKLCIKGDSELLELANSLNDLSDV
FRLTHENLIQEKNRLSSVLSYMSDGVIATNRLGQITMINSTAQRLLNLDRETATQMSILDILDGENPYTYSELLSKTPEI
HLSRRDANDEFVTLRVNFALIRKESGFISGLVAVLHDATEQEKEERERRLFVSNVSHELRTPLTSVKSYLEALDDGALNE
EIAPNFIKVSLDETNRMMRMISDLLALSRIDNKSTQLNVEMTNFTAFMTYILNRFGQIKSQETNPGKSYEIIRDYPVNSI
WVEIDTDKMTQVIDNILNNAIKYSPDGGKITVSMKTTDTQLIVSISDQGLGIPKKDLPLIFDRFYRVDKARSRAQGGTGL
GLSIAKEIVKQHNGFIWAKSEYGKGSTFTIVLPYDQDAMMVDEWEM

Nucleotide


Download         Length: 1341 bp        

>NTDB_id=1130446 STHERMO_RS05485 WP_011227273.1 1036182..1037522(-) (vicK) [Streptococcus thermophilus isolate STH_CIRM_16]
ATGACTAGTATTGGCTTAAATATTACAAGCTTTGAACTGGCCTTACTCTTTATGCTCCTCTTTGTTGCTTTCTATTTCAT
TTTTCTAGCTTATCGTGATTATCAACAGGTCAAAAATATCCGAAAGTTGACTAAGAGAGTCAAATCCCTTATGGCAGGTA
ATTATAATGAAAAATTATGCATAAAGGGAGATTCAGAGCTTTTAGAGCTAGCTAATAGCTTGAATGATTTGTCGGACGTC
TTTCGTTTGACACATGAAAATCTAATCCAGGAAAAAAACCGCTTATCATCTGTTCTTTCGTACATGAGTGACGGGGTTAT
TGCGACCAATCGCCTTGGTCAGATTACTATGATTAATAGTACTGCCCAACGCTTATTGAATTTAGATCGCGAAACTGCGA
CTCAGATGTCTATTTTGGATATATTAGATGGTGAGAATCCCTATACCTATAGTGAATTGTTGTCTAAGACACCCGAAATC
CATCTGTCGCGTCGAGATGCTAACGATGAATTTGTGACGCTACGTGTTAATTTTGCATTAATTCGTAAGGAATCTGGTTT
TATTTCAGGTCTGGTAGCCGTTCTTCATGATGCCACTGAGCAGGAAAAAGAAGAGCGCGAACGCCGTCTCTTCGTATCAA
ATGTTAGTCACGAATTGCGGACGCCTTTAACTTCTGTGAAATCCTATCTTGAAGCGCTTGATGATGGTGCTCTCAACGAA
GAGATTGCTCCAAACTTTATCAAAGTTTCTTTAGATGAAACCAACCGCATGATGCGTATGATTTCTGACCTCTTGGCATT
ATCTCGAATTGACAATAAAAGCACACAGCTTAATGTTGAAATGACAAACTTTACAGCCTTTATGACCTATATCTTGAATC
GGTTTGGTCAAATTAAGAGTCAAGAAACTAATCCAGGTAAGTCTTATGAAATCATTCGAGATTACCCAGTAAACTCTATT
TGGGTGGAAATTGATACTGATAAGATGACCCAGGTCATAGATAATATACTTAATAATGCCATCAAGTATTCTCCTGATGG
TGGGAAAATTACAGTATCTATGAAAACGACAGACACTCAGTTGATTGTTTCTATTTCTGACCAAGGTTTAGGAATTCCTA
AAAAAGATTTACCTCTGATTTTTGACCGTTTTTACCGTGTTGATAAGGCCAGAAGTCGTGCTCAGGGTGGAACAGGACTT
GGCTTGTCCATTGCAAAAGAAATTGTTAAACAACATAATGGCTTCATTTGGGCTAAGAGTGAGTATGGTAAGGGATCAAC
TTTTACAATTGTGCTTCCATATGACCAGGACGCAATGATGGTCGATGAATGGGAGATGTAG

Domains

Predicted by InterproScan.

HAMP domain (HAMP)

(37-79)

PAS fold (PAS)

(94-197)

His Kinase A (phospho-acceptor) domain (HisKA)

(208-272)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(325-435)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vicK Streptococcus mutans UA159

74.396

92.825

0.691
  micB Streptococcus pneumoniae Cp1015

66.051

97.085

0.641

Multiple sequence alignment