Detailed information    

insolico Bioinformatically predicted

Overview

Name   comEA/celA/cilE   Type   Machinery gene
Locus tag   GPW68_RS06810 Genome accession   NZ_LR738723
Coordinates   1364142..1364804 (-) Length   220 a.a.
NCBI ID   WP_023370712.1    Uniprot ID   A0AAP6A5A9
Organism   Streptococcus suis isolate GD-0088     
Function   dsDNA binding to the cell surface (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1359142..1369804
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  GPW68_RS06795 - 1360940..1361596 (-) 657 WP_011922763.1 CBS domain-containing protein -
  GPW68_RS06800 - 1361779..1361904 (-) 126 Protein_1283 IS982 family transposase -
  GPW68_RS06805 comEC/celB 1361921..1364158 (-) 2238 WP_074389299.1 DNA internalization-related competence protein ComEC/Rec2 Machinery gene
  GPW68_RS06810 comEA/celA/cilE 1364142..1364804 (-) 663 WP_023370712.1 helix-hairpin-helix domain-containing protein Machinery gene
  GPW68_RS06815 - 1364871..1365617 (-) 747 WP_023370714.1 lysophospholipid acyltransferase family protein -
  GPW68_RS06820 - 1365763..1367208 (+) 1446 WP_023370716.1 UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--L- lysine ligase -
  GPW68_RS06825 - 1367360..1368160 (+) 801 WP_023370718.1 ABC transporter ATP-binding protein -
  GPW68_RS06830 - 1368157..1369086 (+) 930 WP_074411828.1 ABC transporter substrate-binding protein -

Sequence

Protein


Download         Length: 220 a.a.        Molecular weight: 23513.17 Da        Isoelectric Point: 4.0557

>NTDB_id=1129558 GPW68_RS06810 WP_023370712.1 1364142..1364804(-) (comEA/celA/cilE) [Streptococcus suis isolate GD-0088]
MDTIKTYIEMLKEYKWQIALPTVAGLLMATFLIFSQPAKSDQTGLTDFPQTEQTSSSSDLVEETSTEVSEEPSQLVVDVK
GAVEKPGLYTLEVGSRVNDAVEAAGGLTSQADPKSINLAQKLSDEAVVYVASKDENISVVASTTTSSAMSQEEKNTSLVN
LNTATEADLQTISGIGAKRATDIIAYREANGGFKSVDDLNNVSGIGDKTMESIRPYVTVE

Nucleotide


Download         Length: 663 bp        

>NTDB_id=1129558 GPW68_RS06810 WP_023370712.1 1364142..1364804(-) (comEA/celA/cilE) [Streptococcus suis isolate GD-0088]
ATGGATACGATTAAAACTTATATAGAAATGCTTAAAGAATACAAGTGGCAGATTGCTCTGCCAACAGTGGCTGGCTTGCT
AATGGCGACGTTTTTAATATTCAGCCAACCTGCTAAGTCTGACCAGACAGGACTGACAGACTTTCCACAGACCGAACAAA
CTTCTAGCAGCTCTGACTTGGTCGAGGAAACCAGTACAGAAGTAAGTGAGGAACCCAGCCAGCTGGTTGTTGATGTCAAA
GGAGCGGTGGAAAAACCAGGGCTTTACACTTTAGAAGTAGGTAGTCGTGTCAATGACGCAGTTGAGGCAGCTGGCGGCTT
GACCAGTCAGGCAGACCCAAAGTCTATCAATCTGGCTCAGAAGCTCAGCGATGAGGCGGTGGTCTATGTGGCCAGCAAGG
ACGAAAACATCTCGGTGGTGGCCAGCACGACTACCAGCTCTGCTATGTCCCAAGAAGAAAAAAACACCAGTCTAGTCAAT
CTGAATACGGCGACTGAGGCGGACTTGCAGACCATTTCTGGTATTGGTGCCAAGCGAGCGACGGACATTATCGCCTATCG
TGAGGCCAACGGTGGCTTCAAGTCGGTGGATGACCTCAACAATGTGTCGGGCATCGGCGACAAGACTATGGAAAGCATCC
GGCCTTATGTCACGGTTGAGTAA

Domains

Predicted by InterproScan.

Helix-hairpin-helix motif (HHH_3)

(155-218)

SLBB domain (SLBB)

(76-130)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comEA/celA/cilE Streptococcus pneumoniae Rx1

50.685

99.545

0.505
  comEA/celA/cilE Streptococcus pneumoniae D39

50.685

99.545

0.505
  comEA/celA/cilE Streptococcus pneumoniae R6

50.685

99.545

0.505
  comEA/celA/cilE Streptococcus mitis NCTC 12261

50.685

99.545

0.505
  comEA/celA/cilE Streptococcus pneumoniae TIGR4

49.772

99.545

0.495
  comEA/celA/cilE Streptococcus mitis SK321

47.748

100

0.482
  comEA Streptococcus thermophilus LMD-9

59.494

71.818

0.427
  comEA Lactococcus lactis subsp. cremoris KW2

38.71

98.636

0.382
  comEA Bacillus subtilis subsp. subtilis str. 168

37.915

95.909

0.364

Multiple sequence alignment