Detailed information    

insolico Bioinformatically predicted

Overview

Name   comYB   Type   Machinery gene
Locus tag   GPW68_RS00800 Genome accession   NZ_LR738723
Coordinates   122371..123408 (+) Length   345 a.a.
NCBI ID   WP_257116212.1    Uniprot ID   -
Organism   Streptococcus suis isolate GD-0088     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 117371..128408
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  GPW68_RS00785 - 120073..120438 (+) 366 WP_023369079.1 DUF1033 family protein -
  GPW68_RS00790 - 120473..121423 (-) 951 Protein_118 S66 family peptidase -
  GPW68_RS00795 comYA 121509..122459 (+) 951 WP_044760311.1 competence type IV pilus ATPase ComGA Machinery gene
  GPW68_RS00800 comYB 122371..123408 (+) 1038 WP_257116212.1 competence type IV pilus assembly protein ComGB Machinery gene
  GPW68_RS00805 comYC 123410..123691 (+) 282 WP_074389246.1 competence type IV pilus major pilin ComGC Machinery gene
  GPW68_RS00810 comGD 123672..124079 (+) 408 WP_074389247.1 competence type IV pilus minor pilin ComGD -
  GPW68_RS00815 comYE 124051..124344 (+) 294 WP_024413203.1 competence type IV pilus minor pilin ComGE Machinery gene
  GPW68_RS00820 comGF/cglF 124331..124765 (+) 435 WP_074389248.1 competence type IV pilus minor pilin ComGF Machinery gene
  GPW68_RS00825 comGG 124743..125153 (+) 411 WP_074389249.1 competence type IV pilus minor pilin ComGG -
  GPW68_RS00830 - 125634..126059 (-) 426 WP_226319165.1 ArpU family phage packaging/lysis transcriptional regulator -
  GPW68_RS00835 - 126383..126958 (-) 576 WP_074392204.1 hypothetical protein -
  GPW68_RS11485 - 126979..127152 (-) 174 WP_171840772.1 hypothetical protein -

Sequence

Protein


Download         Length: 345 a.a.        Molecular weight: 38962.96 Da        Isoelectric Point: 9.1394

>NTDB_id=1129529 GPW68_RS00800 WP_257116212.1 122371..123408(+) (comYB) [Streptococcus suis isolate GD-0088]
MRKLIGFLQQDISVFGRQKQKKLPLARQRKVIELFNNLFASGFHLGEIVDFLKRSQLLADPYTQVLSDGLLAGKPFSSLL
ADLRFSDAVVTQVALAEVHGNTSLSLSHIQSYLENVSKVRKKLIEVATYPVILLGFLLLIMLGLKNYLLPQLEEGNAATM
LINHLPTIFLSLCGLSLVGILAGMVWFRKTNKIKVFSCLAALPFFGKLIQTYLTAYYAREWGSLIGQGLDLPQIVGLMQE
QQSQLFREIGQDLEQSLSNGQSFHEHIKTYAFFKRELSLIVEYGQVKSKLGSELTVYAAECWEDFFSRVNRAMQLIQPLV
FLFVALMVVLIYAAMLLPIYQNMEL

Nucleotide


Download         Length: 1038 bp        

>NTDB_id=1129529 GPW68_RS00800 WP_257116212.1 122371..123408(+) (comYB) [Streptococcus suis isolate GD-0088]
ATGCGCAAATTGATCGGCTTTTTGCAGCAGGACATATCAGTCTTCGGCAGGCAGAAACAGAAAAAATTGCCCTTGGCGCG
CCAGCGTAAGGTTATTGAACTGTTTAACAATCTCTTTGCTAGTGGCTTTCATCTGGGGGAGATTGTTGATTTCCTCAAAC
GTAGTCAACTTTTGGCAGATCCCTATACCCAGGTCTTATCGGATGGCCTTCTTGCAGGAAAGCCGTTTTCAAGCTTATTA
GCGGATTTGCGATTTTCAGATGCAGTTGTCACGCAGGTAGCCTTAGCAGAAGTTCACGGCAATACCAGCCTGAGTTTGAG
CCATATCCAGTCTTATCTGGAAAATGTCAGCAAGGTTCGTAAAAAGCTAATTGAGGTAGCGACCTATCCAGTTATCTTGC
TAGGTTTTCTGCTCTTGATTATGCTGGGTTTGAAAAATTACCTTCTGCCTCAGTTGGAGGAAGGCAATGCTGCGACCATG
CTGATCAATCATCTACCGACCATCTTTTTATCCCTCTGTGGACTTAGTTTGGTGGGGATCTTGGCTGGTATGGTTTGGTT
TCGCAAAACCAACAAAATTAAGGTCTTTTCCTGCTTGGCAGCTCTGCCATTTTTCGGAAAACTCATCCAAACCTATCTGA
CGGCCTATTACGCCAGGGAGTGGGGGAGTTTGATTGGGCAAGGATTGGACCTGCCACAGATTGTGGGCTTGATGCAGGAG
CAGCAATCGCAGCTCTTTCGGGAGATTGGGCAGGACCTGGAGCAGTCGCTTTCCAATGGTCAGAGCTTTCACGAACACAT
CAAAACCTACGCCTTTTTTAAGCGGGAGCTGAGCCTCATCGTGGAGTATGGTCAGGTCAAGTCCAAGTTGGGTAGCGAGT
TGACAGTTTATGCGGCCGAGTGTTGGGAGGATTTTTTCTCTCGGGTCAATAGAGCCATGCAGTTGATTCAACCGCTGGTC
TTTCTCTTTGTGGCCTTAATGGTCGTTCTCATCTACGCAGCCATGTTGCTGCCGATTTATCAAAATATGGAGTTGTAA

Domains

Predicted by InterproScan.

Type II secretion system (T2SS), protein F (T2SSF)

(218-338)

Type II secretion system (T2SS), protein F (T2SSF)

(33-150)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comYB Streptococcus gordonii str. Challis substr. CH1

63.743

99.13

0.632
  comGB/cglB Streptococcus mitis NCTC 12261

60.896

97.101

0.591
  comYB Streptococcus mutans UA140

59.531

98.841

0.588
  comYB Streptococcus mutans UA159

59.531

98.841

0.588
  comGB/cglB Streptococcus mitis SK321

60.597

97.101

0.588
  comGB/cglB Streptococcus pneumoniae Rx1

60.299

97.101

0.586
  comGB/cglB Streptococcus pneumoniae D39

60.299

97.101

0.586
  comGB/cglB Streptococcus pneumoniae R6

60.299

97.101

0.586
  comGB/cglB Streptococcus pneumoniae TIGR4

60.299

97.101

0.586
  comGB Lactococcus lactis subsp. cremoris KW2

50.742

97.681

0.496

Multiple sequence alignment