Detailed information    

insolico Bioinformatically predicted

Overview

Name   comYE   Type   Machinery gene
Locus tag   GPW68_RS00815 Genome accession   NZ_LR738723
Coordinates   124051..124344 (+) Length   97 a.a.
NCBI ID   WP_024413203.1    Uniprot ID   A0AAP6A856
Organism   Streptococcus suis isolate GD-0088     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 119051..129344
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  GPW68_RS00785 - 120073..120438 (+) 366 WP_023369079.1 DUF1033 family protein -
  GPW68_RS00790 - 120473..121423 (-) 951 Protein_118 S66 family peptidase -
  GPW68_RS00795 comYA 121509..122459 (+) 951 WP_044760311.1 competence type IV pilus ATPase ComGA Machinery gene
  GPW68_RS00800 comYB 122371..123408 (+) 1038 WP_257116212.1 competence type IV pilus assembly protein ComGB Machinery gene
  GPW68_RS00805 comYC 123410..123691 (+) 282 WP_074389246.1 competence type IV pilus major pilin ComGC Machinery gene
  GPW68_RS00810 comGD 123672..124079 (+) 408 WP_074389247.1 competence type IV pilus minor pilin ComGD -
  GPW68_RS00815 comYE 124051..124344 (+) 294 WP_024413203.1 competence type IV pilus minor pilin ComGE Machinery gene
  GPW68_RS00820 comGF/cglF 124331..124765 (+) 435 WP_074389248.1 competence type IV pilus minor pilin ComGF Machinery gene
  GPW68_RS00825 comGG 124743..125153 (+) 411 WP_074389249.1 competence type IV pilus minor pilin ComGG -
  GPW68_RS00830 - 125634..126059 (-) 426 WP_226319165.1 ArpU family phage packaging/lysis transcriptional regulator -
  GPW68_RS00835 - 126383..126958 (-) 576 WP_074392204.1 hypothetical protein -
  GPW68_RS11485 - 126979..127152 (-) 174 WP_171840772.1 hypothetical protein -
  GPW68_RS00840 - 127466..128902 (-) 1437 WP_156721189.1 phage/plasmid primase, P4 family -

Sequence

Protein


Download         Length: 97 a.a.        Molecular weight: 10727.62 Da        Isoelectric Point: 9.8358

>NTDB_id=1129531 GPW68_RS00815 WP_024413203.1 124051..124344(+) (comYE) [Streptococcus suis isolate GD-0088]
MVAIRKQKNKAYILLESLVALATLVTICSLILSAVDAGRRRQAWELEQQEVLNLAQMAVQTGQDNLALNGVTVQVQRTAD
KIIVFHEGKEVLSVVKK

Nucleotide


Download         Length: 294 bp        

>NTDB_id=1129531 GPW68_RS00815 WP_024413203.1 124051..124344(+) (comYE) [Streptococcus suis isolate GD-0088]
GTGGTCGCTATAAGAAAACAGAAGAATAAGGCTTATATTTTGCTAGAAAGTCTGGTTGCCCTTGCGACTCTAGTGACCAT
TTGCAGCTTGATTTTATCAGCTGTGGATGCAGGTCGCAGGCGACAGGCTTGGGAATTGGAACAACAGGAGGTTCTCAATC
TAGCACAGATGGCTGTTCAGACCGGGCAAGATAACCTAGCCTTAAACGGTGTTACAGTTCAGGTTCAACGAACAGCGGAT
AAGATCATTGTTTTCCACGAGGGAAAGGAGGTTTTATCGGTTGTTAAAAAGTAA

Domains

Predicted by InterproScan.

Type II secretory pathway pseudopilin (ComGE)

(13-94)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comYE Streptococcus mutans UA140

54.639

100

0.546
  comYE Streptococcus mutans UA159

54.639

100

0.546
  comGE/cglE Streptococcus pneumoniae Rx1

41.304

94.845

0.392
  comGE/cglE Streptococcus pneumoniae D39

41.304

94.845

0.392
  comGE/cglE Streptococcus pneumoniae R6

41.304

94.845

0.392
  comGE/cglE Streptococcus pneumoniae TIGR4

41.304

94.845

0.392
  comGE/cglE Streptococcus mitis SK321

40.217

94.845

0.381
  comGE/cglE Streptococcus mitis NCTC 12261

40.217

94.845

0.381

Multiple sequence alignment