Detailed information    

insolico Bioinformatically predicted

Overview

Name   cinA   Type   Machinery gene
Locus tag   GPW68_RS00380 Genome accession   NZ_LR738723
Coordinates   64973..66154 (+) Length   393 a.a.
NCBI ID   WP_023369043.1    Uniprot ID   A0A822VFJ5
Organism   Streptococcus suis isolate GD-0088     
Function   require for competence (predicted from homology)   
Unclear

Genomic Context

Location: 59973..71154
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  GPW68_RS00360 mutL 61076..63013 (+) 1938 WP_012774891.1 DNA mismatch repair endonuclease MutL -
  GPW68_RS00365 ruvA 63052..63642 (+) 591 WP_011921679.1 Holliday junction branch migration protein RuvA -
  GPW68_RS00375 - 64367..64936 (+) 570 WP_012774893.1 DNA-3-methyladenine glycosylase I -
  GPW68_RS00380 cinA 64973..66154 (+) 1182 WP_023369043.1 competence/damage-inducible protein A Machinery gene
  GPW68_RS00385 recA 66206..67354 (+) 1149 WP_023369045.1 recombinase RecA Machinery gene
  GPW68_RS00390 spx 67590..67988 (+) 399 WP_002939362.1 transcriptional regulator Spx -
  GPW68_RS00395 - 68088..68354 (+) 267 WP_002939360.1 IreB family regulatory phosphoprotein -
  GPW68_RS00400 ruvX 68354..68773 (+) 420 WP_002939356.1 Holliday junction resolvase RuvX -
  GPW68_RS00405 - 68785..69117 (+) 333 WP_023369048.1 DUF1292 domain-containing protein -
  GPW68_RS00410 - 69324..69902 (+) 579 WP_012774895.1 nucleotidyltransferase family protein -
  GPW68_RS00415 comX/sigX 69975..70241 (+) 267 WP_014635810.1 hypothetical protein Regulator
  GPW68_RS00420 rpsJ 70564..70872 (+) 309 WP_014735259.1 30S ribosomal protein S10 -

Sequence

Protein


Download         Length: 393 a.a.        Molecular weight: 42819.71 Da        Isoelectric Point: 4.4397

>NTDB_id=1129521 GPW68_RS00380 WP_023369043.1 64973..66154(+) (cinA) [Streptococcus suis isolate GD-0088]
MKAELIAVGTEILTGQIINTNAQFLSEKFAELGIDVYFHTAVGDNEGRLLSTLEVASKRSNMVVLCGGLGPTEDDLTKQT
LATFLGRNLVFDELAMAKLDRLFASRPGRVRTPNNERQAQIVEGSQALQNPAGLAVGGMIEQDGVTYIVLPGPPSELKAM
FSESLLPLLSQSQQQLYSRVLRFFGIGESQLVTVLADLIDKQTDPTLAPYAKVGEVTLRLSTKATSQEEANLRLNQLEED
ILQHDKLADYFYAYGEDNSLAKTVATRLAEKRQTIAIVEQGTGGLLQAELSLALADLPYFSGGKVIGQLGTESGRLSEEA
DCIRQELQADLGLAVSVLIKPESTEDNILAKVYLTLATTSGISQKEVDLGGYSWQYLRQLACLQAWDFVRNTL

Nucleotide


Download         Length: 1182 bp        

>NTDB_id=1129521 GPW68_RS00380 WP_023369043.1 64973..66154(+) (cinA) [Streptococcus suis isolate GD-0088]
ATGAAAGCAGAACTAATCGCCGTTGGGACGGAGATTTTGACAGGTCAAATTATTAATACCAATGCTCAGTTCCTTTCGGA
GAAATTTGCGGAGCTAGGGATTGATGTTTATTTTCATACGGCAGTTGGTGACAATGAAGGCCGTTTATTATCAACCCTTG
AAGTAGCCAGCAAGCGGAGTAATATGGTCGTTCTTTGCGGTGGTTTGGGACCAACTGAGGACGACCTGACCAAGCAGACC
TTGGCGACCTTCTTAGGTAGAAATCTTGTGTTTGATGAGTTGGCTATGGCAAAATTAGACCGTCTCTTTGCCAGTCGCCC
AGGTCGTGTCCGTACACCAAATAATGAACGTCAGGCACAGATTGTGGAGGGAAGTCAGGCGCTACAGAATCCAGCTGGTT
TAGCTGTTGGTGGTATGATTGAGCAAGATGGTGTAACCTATATTGTTTTGCCTGGCCCACCAAGTGAGCTCAAGGCCATG
TTTTCTGAGAGTCTCTTACCTTTACTGTCCCAATCTCAGCAGCAACTTTATTCGCGTGTCCTACGCTTTTTTGGAATTGG
CGAAAGCCAGTTGGTGACTGTTTTGGCGGACTTGATTGACAAGCAGACAGACCCAACTCTTGCTCCTTATGCAAAAGTTG
GAGAGGTGACTTTACGCTTGTCCACCAAAGCGACCAGCCAAGAAGAAGCAAATCTACGTTTAAATCAGTTGGAAGAAGAC
ATCTTACAACATGACAAACTGGCAGACTATTTCTATGCCTACGGAGAGGACAATAGTTTGGCCAAAACGGTAGCGACTCG
TTTGGCGGAGAAAAGACAAACCATCGCTATCGTCGAACAGGGGACAGGTGGTCTCTTGCAAGCTGAATTGAGCCTGGCTT
TGGCTGATCTGCCGTATTTTAGCGGAGGAAAAGTCATCGGTCAGCTAGGGACAGAATCGGGCAGGCTATCAGAGGAAGCT
GACTGCATTCGGCAGGAGCTGCAAGCTGATTTGGGTTTGGCTGTGTCTGTGCTTATCAAACCGGAATCAACAGAGGACAA
CATACTTGCAAAAGTATATCTCACTTTGGCTACGACCTCGGGTATTTCCCAAAAAGAGGTAGATTTAGGTGGTTATTCGT
GGCAATACCTTCGCCAGCTTGCTTGTCTGCAGGCCTGGGATTTTGTACGAAACACTTTGTGA

Domains

Predicted by InterproScan.

Damage-inducible protein CinA KH domain (CinA_KH)

(178-253)

Probable molybdopterin binding domain (MoCF_biosynth)

(5-170)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A822VFJ5

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  cinA Streptococcus suis isolate S10

97.201

100

0.972
  cinA Streptococcus mutans UA159

56.691

100

0.593
  cinA Streptococcus pneumoniae R6

55.769

100

0.59
  cinA Streptococcus mitis SK321

55.769

100

0.59
  cinA Streptococcus pneumoniae TIGR4

55.769

100

0.59
  cinA Streptococcus pneumoniae Rx1

55.769

100

0.59
  cinA Streptococcus mitis NCTC 12261

55.529

100

0.588
  cinA Streptococcus pneumoniae D39

55.529

100

0.588
  cinA Bacillus subtilis subsp. subtilis str. 168

40.153

99.491

0.399

Multiple sequence alignment