Detailed information    

insolico Bioinformatically predicted

Overview

Name   cinA   Type   Machinery gene
Locus tag   M395_RS12220 Genome accession   NZ_CP006030
Coordinates   2527554..2528795 (-) Length   413 a.a.
NCBI ID   WP_002373450.1    Uniprot ID   A0A4Y3JRI6
Organism   Enterococcus faecium T110     
Function   facilitate localization of RecA (predicted from homology)   
Homologous recombination

Genomic Context

Location: 2522554..2533795
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  M395_RS12205 (M395_12385) proC 2523536..2524342 (+) 807 WP_038399140.1 pyrroline-5-carboxylate reductase -
  M395_RS12210 (M395_12390) rny 2524421..2525977 (-) 1557 WP_002287336.1 ribonuclease Y -
  M395_RS12215 (M395_12395) recA 2526396..2527445 (-) 1050 WP_002293077.1 recombinase RecA Machinery gene
  M395_RS12220 (M395_12400) cinA 2527554..2528795 (-) 1242 WP_002373450.1 competence/damage-inducible protein A Machinery gene
  M395_RS12225 (M395_12405) pgsA 2528966..2529544 (-) 579 WP_002310442.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  M395_RS12230 (M395_12410) - 2529753..2530676 (-) 924 WP_002310444.1 RodZ domain-containing protein -
  M395_RS12235 (M395_12415) yfmH 2531291..2532577 (-) 1287 WP_038399142.1 EF-P 5-aminopentanol modification-associated protein YfmH -

Sequence

Protein


Download         Length: 413 a.a.        Molecular weight: 45434.86 Da        Isoelectric Point: 4.7550

>NTDB_id=112932 M395_RS12220 WP_002373450.1 2527554..2528795(-) (cinA) [Enterococcus faecium T110]
MKAEIIAVGTELLLGQVVNTNATFLSEQLADLGIEVYYQTVVGDNQQRLEELIALAETRSELILLCGGLGPTEDDLTKEA
TAAHLGKSLIQNTEGYKKLLAYFETTHRKMTKNNLQQSQIIEGGVPLPNRTGLALGTFYQTDTHAYILLPGPPNELKPMF
VEQVRPLLEERFPSEEKLISKVLRFYGIGESRLVTELKDLIETQINPTIAPYAKPNEVTLRLTVKTKDVQAGNQALLALE
EKIQERVGEYFYGYGDDNSLAKVVVELLKENKQTVTAAESLTAGAFQAALGDIAGVSEVFPGGFVTYSLQTKAGFLEIDP
ELLAEYGTVSKECVEQMAIQAREIARTDYSVAFTGVAGPDTLEGHPAGTVWIAISSKDGVVSEKYHFGRDRAAIRYNAVM
QGFDLLRKQLLRK

Nucleotide


Download         Length: 1242 bp        

>NTDB_id=112932 M395_RS12220 WP_002373450.1 2527554..2528795(-) (cinA) [Enterococcus faecium T110]
ATGAAAGCAGAAATAATAGCTGTCGGAACAGAACTTTTACTAGGACAAGTCGTGAATACGAATGCCACTTTCTTGTCAGA
ACAGCTAGCTGATCTAGGTATCGAAGTTTATTATCAGACAGTCGTAGGAGATAATCAGCAACGTTTAGAAGAGTTGATTG
CTCTAGCTGAAACAAGAAGTGAACTCATACTCTTATGTGGCGGATTAGGACCGACAGAAGATGACCTGACAAAAGAAGCA
ACTGCGGCTCACCTCGGTAAGTCTCTCATACAAAATACGGAAGGATACAAAAAATTATTGGCATATTTTGAAACAACCCA
TCGAAAAATGACCAAAAACAATCTGCAACAGTCCCAAATCATCGAAGGCGGGGTTCCTCTACCAAATCGTACAGGGCTTG
CTTTAGGGACTTTTTATCAAACAGATACACATGCATATATCCTTCTTCCCGGTCCGCCTAATGAGTTGAAACCAATGTTT
GTGGAACAAGTACGTCCTTTACTAGAGGAACGTTTTCCTTCTGAAGAAAAACTGATTTCTAAAGTTTTGCGCTTTTATGG
GATTGGTGAATCGCGACTGGTCACTGAACTAAAAGATCTAATCGAGACACAGATCAATCCAACGATCGCTCCTTATGCCA
AACCAAATGAAGTGACATTGCGTCTAACAGTGAAAACAAAGGATGTTCAGGCAGGAAATCAAGCTCTTTTAGCATTGGAA
GAAAAGATTCAAGAACGAGTAGGAGAATATTTTTATGGATATGGCGATGATAATTCGTTAGCAAAAGTCGTAGTGGAACT
GCTGAAAGAAAACAAGCAGACTGTAACAGCGGCGGAAAGCTTGACAGCCGGTGCCTTCCAAGCCGCATTGGGCGATATTG
CTGGTGTATCTGAAGTATTTCCAGGCGGCTTCGTTACCTACTCGCTCCAAACAAAAGCTGGTTTTCTGGAGATTGATCCG
GAGCTATTAGCAGAATATGGAACAGTCAGCAAAGAATGTGTGGAGCAGATGGCCATTCAAGCACGTGAGATAGCAAGAAC
AGATTACAGTGTAGCTTTCACCGGAGTGGCTGGACCGGACACGTTAGAAGGTCACCCTGCAGGAACAGTATGGATCGCTA
TTTCATCTAAAGATGGCGTGGTTTCAGAAAAATATCATTTTGGCAGAGACCGTGCGGCTATCAGATATAATGCGGTTATG
CAAGGATTTGATCTTTTGAGAAAACAGCTTTTAAGAAAATGA

Domains

Predicted by InterproScan.

Damage-inducible protein CinA KH domain (CinA_KH)

(180-253)

Probable molybdopterin binding domain (MoCF_biosynth)

(5-169)

Competence-damaged protein (CinA)

(258-410)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A4Y3JRI6

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  cinA Streptococcus mitis SK321

51.905

100

0.528
  cinA Streptococcus pneumoniae TIGR4

51.667

100

0.525
  cinA Streptococcus pneumoniae D39

51.429

100

0.523
  cinA Streptococcus pneumoniae Rx1

51.429

100

0.523
  cinA Streptococcus pneumoniae R6

51.429

100

0.523
  cinA Streptococcus mitis NCTC 12261

51.429

100

0.523
  cinA Streptococcus mutans UA159

51.807

100

0.521
  cinA Bacillus subtilis subsp. subtilis str. 168

47.573

99.758

0.475
  cinA Streptococcus suis isolate S10

42.029

100

0.421

Multiple sequence alignment