Detailed information    

insolico Bioinformatically predicted

Overview

Name   cinA   Type   Machinery gene
Locus tag   FXY97_RS04625 Genome accession   NZ_LR698954
Coordinates   892788..894029 (+) Length   413 a.a.
NCBI ID   WP_014569352.1    Uniprot ID   -
Organism   Lacticaseibacillus rhamnosus isolate MGYG-HGUT-01293     
Function   facilitate localization of RecA (predicted from homology)   
Homologous recombination

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
ICE 884872..933759 892788..894029 within 0


Gene organization within MGE regions


Location: 884872..933759
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  FXY97_RS04595 - 885370..887670 (+) 2301 WP_014569347.1 DNA translocase FtsK -
  FXY97_RS04600 yfmF 887679..888941 (+) 1263 WP_014569348.1 EF-P 5-aminopentanol modification-associated protein YfmF -
  FXY97_RS04605 yfmH 888938..890230 (+) 1293 WP_014569349.1 EF-P 5-aminopentanol modification-associated protein YfmH -
  FXY97_RS04610 ymfI 890230..890958 (+) 729 WP_014569350.1 elongation factor P 5-aminopentanone reductase -
  FXY97_RS04615 - 891045..891980 (+) 936 WP_005688668.1 helix-turn-helix domain-containing protein -
  FXY97_RS04620 pgsA 891977..892567 (+) 591 WP_014569351.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  FXY97_RS04625 cinA 892788..894029 (+) 1242 WP_014569352.1 competence/damage-inducible protein A Machinery gene
  FXY97_RS04630 recA 894081..895133 (+) 1053 WP_005688187.1 recombinase RecA Machinery gene
  FXY97_RS04640 rny 895758..897329 (+) 1572 WP_005684479.1 ribonuclease Y -
  FXY97_RS04645 - 897418..898074 (-) 657 WP_029943817.1 YigZ family protein -
  FXY97_RS04650 - 898102..899367 (+) 1266 WP_014569356.1 DEAD/DEAH box helicase -
  FXY97_RS04655 - 899526..900044 (+) 519 WP_005688681.1 ComF family protein -
  FXY97_RS04660 hpf 900236..900793 (+) 558 WP_005684485.1 ribosome hibernation-promoting factor, HPF/YfiA family -
  FXY97_RS04675 secA 901376..903739 (+) 2364 WP_005684487.1 preprotein translocase subunit SecA -
  FXY97_RS04680 prfB 903881..904997 (+) 1117 WP_154241369.1 peptide chain release factor 2 -
  FXY97_RS04685 ftsE 905074..905760 (+) 687 WP_005684489.1 cell division ATP-binding protein FtsE -
  FXY97_RS04690 ftsX 905750..906637 (+) 888 WP_005684490.1 permease-like cell division protein FtsX -
  FXY97_RS15410 - 906715..906852 (+) 138 WP_014569359.1 hypothetical protein -
  FXY97_RS04695 - 906908..908005 (+) 1098 WP_014569360.1 PDZ domain-containing protein -
  FXY97_RS04700 - 908002..908706 (+) 705 WP_005688690.1 response regulator transcription factor -
  FXY97_RS04705 pnpS 908699..910366 (+) 1668 WP_014569361.1 two-component system histidine kinase PnpS -
  FXY97_RS04710 - 910456..911322 (+) 867 WP_005684496.1 phosphate ABC transporter substrate-binding protein PstS family protein -
  FXY97_RS04715 pstC 911470..912393 (+) 924 WP_005684497.1 phosphate ABC transporter permease subunit PstC -
  FXY97_RS04720 pstA 912390..913274 (+) 885 WP_005684499.1 phosphate ABC transporter permease PstA -
  FXY97_RS04725 pstB 913345..914163 (+) 819 WP_005713669.1 phosphate ABC transporter ATP-binding protein PstB -
  FXY97_RS04730 pstB 914173..914937 (+) 765 WP_005684501.1 phosphate ABC transporter ATP-binding protein PstB -
  FXY97_RS04735 phoU 914948..915625 (+) 678 WP_005684502.1 phosphate signaling complex protein PhoU -
  FXY97_RS04740 - 915879..916757 (-) 879 WP_048653158.1 IS3 family transposase -
  FXY97_RS04745 - 916754..917482 (-) 729 WP_014569363.1 helix-turn-helix domain-containing protein -
  FXY97_RS04750 liaX 918051..919541 (+) 1491 WP_014569364.1 daptomycin-sensing surface protein LiaX -
  FXY97_RS04755 - 919553..919813 (+) 261 WP_005688700.1 hypothetical protein -
  FXY97_RS04760 - 919816..920151 (+) 336 WP_005684507.1 phage holin family protein -
  FXY97_RS04765 hprK 920418..921377 (+) 960 WP_005684508.1 HPr(Ser) kinase/phosphatase -
  FXY97_RS04770 lgt 921379..922206 (+) 828 WP_014569365.1 prolipoprotein diacylglyceryl transferase -
  FXY97_RS04775 - 922217..923272 (+) 1056 WP_014569366.1 NAD(P)H-dependent glycerol-3-phosphate dehydrogenase -
  FXY97_RS04780 trxB 923338..924285 (+) 948 WP_005684511.1 thioredoxin-disulfide reductase -
  FXY97_RS04785 - 924537..926264 (+) 1728 WP_014569367.1 phospho-sugar mutase -
  FXY97_RS04790 - 926724..927371 (+) 648 WP_014569368.1 YfbR-like 5'-deoxynucleotidase -
  FXY97_RS04795 uvrB 927642..929657 (+) 2016 WP_005688715.1 excinuclease ABC subunit UvrB -
  FXY97_RS04800 uvrA 929838..932732 (+) 2895 WP_014569369.1 excinuclease ABC subunit UvrA -
  FXY97_RS04805 - 932934..933473 (+) 540 WP_014569370.1 HdeD family acid-resistance protein -

Sequence

Protein


Download         Length: 413 a.a.        Molecular weight: 44472.12 Da        Isoelectric Point: 7.2504

>NTDB_id=1128629 FXY97_RS04625 WP_014569352.1 892788..894029(+) (cinA) [Lacticaseibacillus rhamnosus isolate MGYG-HGUT-01293]
MQAEIIAIGTEILMGQITNTNGAYMAKQLATLGIASYHQQVVGDNAKRLADAISLAEQRSDIVILIGGLGPTPDDLTKQT
LAAHLNLPLVEDADAMAKLAARVKQQQRPMTPNNRLQAMYPQGAIVLANRVGLAVGAWVEQRQHAYVLLPGPPKEFVPMV
DHELLPRLAKYSGHQEVLESRVMRFFGIGESQLVTDLSDLIANQTNPTLATYIKDHEVTVRVTASGKTQAEAAAKLEPMI
GIIMDREGRYFYGYGDDNSLAQELVKALAASDKQISAAESLTAGAFQAALGDVPGVSAYFKGGFVTYALATKAAFLNIDA
RQLSEHGVVSEFTAKAMAEHARQRAAADIAVSFTGVAGPDKLEGQPAGTVWIGLARLGEKPIAQVYHFPGGRNDVRKRAV
MTGMMMVLKRLRE

Nucleotide


Download         Length: 1242 bp        

>NTDB_id=1128629 FXY97_RS04625 WP_014569352.1 892788..894029(+) (cinA) [Lacticaseibacillus rhamnosus isolate MGYG-HGUT-01293]
ATGCAAGCAGAAATTATTGCTATCGGAACGGAAATTCTGATGGGACAAATTACAAATACAAATGGCGCGTATATGGCTAA
ACAACTGGCTACATTAGGTATTGCGAGCTATCATCAACAGGTTGTTGGGGATAATGCAAAACGACTGGCTGACGCGATAA
GTTTGGCGGAACAACGCAGTGATATCGTTATTTTGATTGGTGGTTTAGGACCAACACCGGATGATTTAACGAAGCAAACC
CTAGCCGCACACCTGAATTTACCCTTGGTGGAAGACGCTGACGCTATGGCCAAGTTGGCTGCGCGGGTTAAACAACAGCA
ACGTCCAATGACACCCAATAATCGCCTGCAAGCGATGTATCCCCAAGGCGCAATCGTATTGGCCAATCGTGTCGGGTTGG
CGGTCGGCGCATGGGTTGAGCAGCGCCAACACGCCTATGTTTTATTGCCGGGACCACCTAAAGAGTTTGTGCCGATGGTT
GATCATGAACTGTTGCCACGACTGGCAAAATATAGCGGGCATCAAGAAGTTTTGGAAAGTCGCGTGATGCGTTTCTTTGG
TATCGGCGAATCGCAACTTGTGACAGACTTAAGTGATTTAATTGCCAACCAGACGAATCCGACACTTGCAACTTATATAA
AAGATCATGAGGTGACAGTTCGGGTAACTGCGAGTGGCAAAACACAAGCAGAAGCCGCGGCGAAACTTGAGCCAATGATC
GGCATCATTATGGATCGTGAAGGTCGCTACTTTTACGGCTACGGTGACGATAACAGTCTTGCCCAGGAATTAGTCAAAGC
ATTGGCGGCTAGTGATAAGCAAATTAGTGCCGCTGAAAGTCTGACTGCAGGTGCATTTCAAGCGGCATTGGGAGACGTTC
CGGGAGTCTCGGCTTATTTCAAAGGCGGCTTCGTTACGTACGCTTTAGCGACAAAAGCTGCATTTTTAAATATTGATGCC
CGTCAGCTATCAGAACATGGTGTGGTGAGTGAATTTACTGCCAAAGCAATGGCAGAGCATGCTCGTCAACGAGCGGCGGC
AGACATTGCCGTTAGTTTTACCGGAGTTGCCGGTCCTGACAAGCTGGAAGGACAGCCAGCCGGCACCGTCTGGATTGGTT
TGGCGCGGTTAGGAGAGAAACCAATAGCACAAGTTTATCATTTTCCGGGTGGGCGAAATGACGTCCGCAAGCGCGCCGTT
ATGACGGGGATGATGATGGTGTTGAAGCGTTTACGCGAATAA

Domains

Predicted by InterproScan.

Probable molybdopterin binding domain (MoCF_biosynth)

(5-169)

Competence-damaged protein (CinA)

(258-410)

Damage-inducible protein CinA KH domain (CinA_KH)

(180-253)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  cinA Streptococcus mitis SK321

52.019

100

0.53
  cinA Streptococcus mitis NCTC 12261

52.019

100

0.53
  cinA Streptococcus pneumoniae TIGR4

51.544

100

0.525
  cinA Streptococcus pneumoniae R6

51.069

100

0.521
  cinA Streptococcus pneumoniae Rx1

51.069

100

0.521
  cinA Streptococcus mutans UA159

51.442

100

0.518
  cinA Streptococcus pneumoniae D39

50.831

100

0.518
  cinA Bacillus subtilis subsp. subtilis str. 168

44.66

99.758

0.446
  cinA Streptococcus suis isolate S10

42.593

91.525

0.39

Multiple sequence alignment